Existence of Manserin, a Secretogranin II-Derived Neuropeptide, in the Rat Inner Ear: Relevance to Modulation of Auditory and Vestibular System

Journal of Histochemistry and Cytochemistry

Volumn 60, Issue 1, 2012, Pages 69-75

  Ida Eto, Michiru ^a   Oyabu, Akiko ^a   Ohkawara, Takeshi ^a   Tashiro, Yasura ^a   Narita, Naoko ^b   Narita, Masaaki ^a  

^a MIE UNIVERSITY   (Japan)

^b BUNKYO UNIVERSITY   (Japan)

Author keywords

immunohistochemistry; inner ear; manserin; neuropeptide; organ of Corti; semicircular canal; spiral ganglion; vestibular macula

Indexed keywords

MANSERIN; NEUROPEPTIDE; UNCLASSIFIED DRUG; MANSERIN, RAT; PEPTIDE FRAGMENT; SECRETOGRANIN 2, RAT; SECRETOGRANIN II;

AMPULLARY CREST; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUDITORY SYSTEM; CORTI ORGAN; HYPOPHYSIS; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INNER EAR; MALE; NERVE CELL; NERVE ENDING; NEUROENDOCRINE SYSTEM; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RAT; SACCULUS; SEMICIRCULAR CANAL; SPIRAL GANGLION; SYNAPSE; UTRICLE; VESTIBULAR SYSTEM; ANIMAL; ANTIBODY SPECIFICITY; AUDITORY NERVOUS SYSTEM; CYTOLOGY; METABOLISM; VESTIBULE; WISTAR RAT;

RATTUS; RATTUS NORVEGICUS;

ANIMALS; AUDITORY PATHWAYS; EAR, INNER; IMMUNOHISTOCHEMISTRY; MALE; NEUROPEPTIDES; ORGAN OF CORTI; ORGAN SPECIFICITY; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; SECRETOGRANIN II; SPIRAL GANGLION; VESTIBULE, LABYRINTH;

EID: 84856688153     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/0022155411425688     Document Type: Article

References (27)

1. Anouar Y,Desmoucelles C,Yon L,Leprince J,Breault L,Gallo-Payet N,Vaudry H.Identification of a novel secretogranin II-derived peptide (SgII187-252) in adult and fetal human adrenal glands using antibodies against the human recombinant peptide.J Clin Endocrinol Metab. 1998;83:2944-2951.
2. Ashmore J.Cochlear outer hair cell motility.Physiol Rev. 2008;88:173-210.
3. Drescher MJ,Drescher DG,Khan KM,Hatfield JS,Ramakrishnan NA,Abu-Hamdan MD,Lemonnier LA.Pituitary adenylyl cyclase-activating polypeptide (PACAP) and its receptor (PAC1-R) are positioned to modulate afferent signaling in the cochlea.Neuroscience. 2006;142:139-164.
4. Gomide VC,de Francisco AC,Chadi G.Localization of neurotensin immunoreactivity in neurons and organ of Corti of rat cochlea.Hear Res. 2005;205:1-6.
5. Gomide VC,Laureano MR,Silveira GA,Chadi G.Neuropeptide Y in rat spiral ganglion neurons and inner hair cells of organ of corti and effects of a nontraumatic acoustic stimulation.Int J Neurosci. 2009;119:508-530.
6. Hafidi A.Peripherin-like immunoreactivity in type II spiral ganglion cell body and projections.Brain Res. 1998;805:181-190.
7. Hain TC, Helminski JO. 2007. Anatomy and physiology of the normal vestibular system. In: Herdman SJ, editor. Vestibular rehabilitation. 3rd ed. Philadelphia: F. A. Davis Company. p. 2-18.
8. Hasson T,Gillespie PG,Garcia JA,MacDonald RB,Zhao Y,Yee AG,Mooseker MS,Corey DP.Unconventional myosins in inner-ear sensory epithelia.J Cell Biol. 1997;137:1287-1307.
9. Hökfelt T,Bartfai T,Bloom F.Neuropeptides: opportunities for drug discovery.Lancet Neurol. 2003;2:463-472.
10. Horner KC.The emotional ear in stress.Neurosci Biobehav Rev. 2003;27:437-446.
11. Kamada N,Tano K,Oyabu A,Imura Y,Narita N,Tashiro Y,Uchida A,Komada Y,Narita M.Immunohistochemical localization of manserin, a novel neuropeptide derived from secretogranin II, in rat adrenal gland, and its upregulation by physical stress.Int J Pept Res Ther. 2010;16:55-61.
12. Khalifa SA,Friberg U,Illing RB,Rask-Andersen H.Synaptophysin immunohistochemistry in the human cochlea.Hear Res. 2003;185:35-42.
13. Marksteiner J,Kirchmair R,Mahata SK,Mahata M,Fischer-Colbrie R,Hogue-Angeletti R,Saria A,Winkler H.Distribution of secretoneurin, a peptide derived from secretogranin II, in rat brain: an immunocytochemical and radioimmunological study.Neuroscience. 1993;54:923-944.
14. Meza G.Modalities of GABA and glutamate neurotransmission in the vertebrate inner ear vestibule.Neurochem Res. 2008;33:1634-1642.
15. Minor LB.Physiological principles of vestibular function on earth and in space.Otolaryngol Head Neck Surg. 1998;118:S5-S15.
16. Patuzzi R,Robertson D.Tuning in the mammalian cochlea.Physiol Rev. 1988;68:1009-1082.
17. Raphael Y,Altschuler RA.Structure and innervation of the cochlea.Brain Res Bull. 2003;60:397-422.
18. Rusznak Z,Szucs G.Spiral ganglion neurons: an overview of morphology, firing behavior, ionic channels and function. Pflugers Arch. 2009;457:1303-1325.
19. Rutka JA. 2004. Anatomy and physiology of the vestibular system. In: Roland PS, Rutka JA, editors. Ototoxicity. London: B. C. Decker. p. 20-27.
20. Schubert MC,Minor LB. Vestibulo-ocular physiology underlying vestibular hypofunction.Phys Ther. 2004;84:373-385.
21. Sekerkova G,Zheng L,Mugnaini E,Bartles JR.Espin actin-cytoskeletal proteins are in rat type I spiral ganglion neurons and include splice-isoforms with a functional nuclear localization signal.J Comp Neurol. 2008;509:661-676.
22. Tano K,Oyabu A,Tashiro Y,Kamada N,Narita N,Nasu F,Narita M.Manserin, a secretogranin II-derived peptide, distributes in the rat endocrine pancreas colocalized with islet-cell specific manner.Histochem Cell Biol. 2010;134:53-57.
23. Thiers FA,Nadol JB,Liberman MC.Reciprocal synapses between outer hair cells and their afferent terminals: evidence for a local neural network in the mammalian cochlea.J Assoc Res Otolaryngol. 2008;9:477-489.
24. Waka N,Knipper M,Engel J.Localization of the calcium channel subunits Cav1.2 (alpha1C) and Cav2.3 (alpha1E) in the mouse organ of Corti.Histol Histopathol. 2003;18:1115-1123.
25. Yajima A,Ikeda M,Miyazaki K,Maeshima T,Narita N,Narita M.Manserin, a novel peptide from secretogranin II in the neuroendocrine system.Neuroreport. 2004;15:1755-1759.
26. Yajima A,Narita N,Narita M.Recently identified a novel neuropeptide manserin colocalize with the TUNEL-positive cells in the top villi of the rat duodenum.J Pept Sci. 2008;14:773-776.
27. Ylikoski J,Pirvola U,Häppölä O,Panula P,Virtanen I.Immunohistochemical demonstration of neuroactive substances in the inner ear of rat and guinea pig.Acta Otolaryngol. 1989;107:417-423.