Postoperative intraperitoneal 5-fluoro-2′-deoxyuridine added to chemoradiation in patients curatively resected (R0) for locally advanced gastric and gastroesophageal junction adenocarcinoma

Annals of Surgical Oncology

Volumn 19, Issue 2, 2012, Pages 478-485

  Cohen, Deirdre J ^a   Newman, Elliot ^a   Iqbal, Syma ^b   Chang, Richard Y ^a   Potmesil, Milan ^a   Ryan, Theresa ^a   Donahue, Bernadine ^a   Chandra, Anurag ^a   Liu, Mengling ^c   Utate, Minerva ^a   Hiotis, Spiros ^d   Pachter, Leon H ^a   Hochster, Howard ^e   Muggia, Franco ^a  

^a NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MOUNT SINAI MEDICAL CENTER   (United States)

^e YALE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLOXURIDINE; FLUOROURACIL; FOLINIC ACID;

ADJUVANT THERAPY; ADULT; ARTICLE; CANCER CHEMOTHERAPY; CANCER MORTALITY; CANCER PATIENT; CANCER RADIOTHERAPY; CANCER STAGING; CANCER SURGERY; CANCER SURVIVAL; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE FREE SURVIVAL; ESOPHAGUS CARCINOMA; EXTERNAL BEAM RADIOTHERAPY; FEASIBILITY STUDY; FOLLOW UP; HUMAN; LOWER ESOPHAGUS SPHINCTER; LYMPH NODE; MALE; OVERALL SURVIVAL; PILOT STUDY; STOMACH ADENOCARCINOMA;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHEMOTHERAPY, ADJUVANT; COMBINED MODALITY THERAPY; ESOPHAGOGASTRIC JUNCTION; FEASIBILITY STUDIES; FEMALE; FLOXURIDINE; FLUOROURACIL; FOLLOW-UP STUDIES; GASTRECTOMY; HUMANS; LEUCOVORIN; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; PILOT PROJECTS; POSTOPERATIVE PERIOD; PROGNOSIS; RADIOTHERAPY DOSAGE; STOMACH NEOPLASMS; SURVIVAL RATE;

EID: 84856663517     PISSN: 10689265     EISSN: 15344681     Source Type: Journal    
DOI: 10.1245/s10434-011-1940-8     Document Type: Article

References (40)

1. DM Parkin F Bray J Ferlay P Pisani 2005 Global cancer statistics, 2002 CA Cancer J Clin 55 74 108 15761078 10.3322/canjclin.55.2.74
2. SA Hundahl JL Phillips HR Menck 2000 The National Cancer Data Base Report on poor survival of U.S. gastric carcinoma patients treated with gastrectomy. Fifth Edition American joint committee on cancer staging, proximal disease, and the "different disease" hypothesis Cancer 88 921 932 10679663 10.1002/(SICI)1097-0142(20000215)88:4<921::AID-CNCR24>3.0.CO;2-S 1:STN:280:DC%2BD3c7ksFOiuw%3D%3D
3. JS Macdonald SR Smalley J Benedetti SA Hundahl NC Estes GN Stemmermann DG Haller JA Ajani LL Gunderson JM Jessup JA Martenson 2001 Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction N Engl J Med. 345 725 730 11547741 10.1056/NEJMoa010187 1:STN:280:DC%2BD3Mvps1Cqug%3D%3D
4. HH Hartgrink CJ van de Velde H Putter JJ Bonenkamp E Klein Kranenbarg I Songun K Welvaart JH van Krieken S Meijer JT Plukker PJ van Elk H Obertop DJ Gouma JJ van Lanschot CW Taat PW de Graaf MF von Meyenfeldt H Tilanus M Sasako 2004 Extended lymph node dissection for gastric cancer: who may benefit? Final results of the randomized Dutch gastric cancer group trial J Clin Oncol 22 2069 2077 15082726 10.1200/JCO.2004.08.026 1:STN:280:DC%2BD2c3ntVOgsQ%3D%3D
5. F Bozzetti E Marubini G Bonfanti R Miceli C Piano L Gennari 1999 Subtotal versus total gastrectomy for gastric cancer: five-year survival rates in a multicenter randomized Italian trial. Italian Gastrointestinal Tumor Study Group Ann Surg. 230 170 178 10450730 10.1097/00000658-199908000-00006 1:STN:280:DyaK1Mznsl2guw%3D%3D
6. I Gockel S Pietzka U Gonner G Hommel T Junginger 2005 Subtotal or total gastrectomy for gastric cancer: impact of the surgical procedure on morbidity and prognosis-analysis of a 10-year experience Langenbecks Arch Surg. 390 148 155 15711817 10.1007/s00423-005-0544-9
7. A Cuschieri S Weeden J Fielding J Bancewicz J Craven V Joypaul M Sydes P Fayers 1999 Patient survival after D1 and D2 resections for gastric cancer: long-term results of the MRC randomized surgical trial. Surgical Co-operative Group Br J Cancer. 79 1522 1530 10188901 10.1038/sj.bjc.6690243 1:STN:280:DyaK1M3gt1Ortg%3D%3D
8. JJ Bonenkamp J Hermans M Sasako CJ van de Velde K Welvaart I Songun S Meyer JT Plukker P Van Elk H Obertop DJ Gouma JJ van Lanschot CW Taat PW de Graaf MF von Meyenfeldt H Tilanus 1999 Extended lymph-node dissection for gastric cancer N Engl J Med. 340 908 914 10089184 10.1056/NEJM199903253401202 1:STN:280:DyaK1M7ntlertQ%3D%3D
9. Y Kodera RE Schwarz A Nakao 2002 Extended lymph node dissection in gastric carcinoma: where do we stand after the Dutch and British randomized trials? J Am Coll Surg. 195 855 864 12495318 10.1016/S1072-7515(02)01496-5
10. SR Smalley L Gunderson J Tepper JA Martenson Jr B Minsky C Willett T Rich 2002 Gastric surgical adjuvant radiotherapy consensus report: rationale and treatment implementation Int J Radiat Oncol Biol Phys. 52 283 293 11872272 10.1016/S0360-3016(01)02646-3
11. F Roviello D Marrelli G de Manzoni P Morgagni A Di Leo L Saragoni A De Stefano 2003 Prospective study of peritoneal recurrence after curative surgery for gastric cancer Br J Surg. 90 1113 1119 12945079 10.1002/bjs.4164 1:STN:280:DC%2BD3svgsFemsg%3D%3D
12. Hundahl SA, Macdonald JS, Smalley SR. Gastric cancer. In: Chang AE, Ganz PA, Hays DF, Kinsella TJ, Pass HI, Schiller JH, Stone RM, Strecher VJ, editors. Oncology: an evidence-based approach. New York: Springer; 2006. p. 680-703.
13. L Gianni I Panzini D Tassinari AM Mianulli F Desiderio A Ravaioli 2001 Meta-analyses of randomized trials of adjuvant chemotherapy in gastric cancer Ann Oncol. 12 1178 1180 11583204 1:STN:280:DC%2BD3MrjsFegtw%3D%3D
14. E Mari I Floriani A Tinazzi A Buda M Belfiglio M Valentini S Cascinu S Barni R Labianca V Torri 2000 Efficacy of adjuvant chemotherapy after curative resection for gastric cancer: a meta-analysis of published randomised trials. A study of the GISCAD (Gruppo Italiano per lo Studio dei Carcinomi dell'Apparato Digerente) Ann Oncol 11 837 843 10997811 10.1023/A:1008377101672 1:STN:280:DC%2BD3cvks1SgtA%3D%3D
15. I Panzini L Gianni PP Fattori D Tassinari M Imola P Fabbri V Arcangeli G Drudi D Canuti F Fochessati A Ravaioli 2002 Adjuvant chemotherapy in gastric cancer: a meta-analysis of randomized trials and a comparison with previous meta-analyses Tumori. 88 21 27 12004845 1:CAS:528:DC%2BD38Xjt1ChtLo%3D
16. P Das N Fukami JA Ajani 2006 Combined modality therapy of localized gastric and esophageal cancers J Natl Compr Canc Netw. 4 375 382 16569390 1:CAS:528:DC%2BD1cXmtFOrtbc%3D
17. Guller U, Baxter N, Law CH, Swallow CJ, Coburn N. Trends in adjuvant treatment of gastric cancer: an analysis of 9,528 patients. In: Proceedings of the American Society of Clinical Oncology, Gastrointestinal Symposia, Orlando; 2007.
18. P Crookes CG Leichman L Leichman M Tan L Laine S Stain J Baranda Y Casagrande S Groshen H Silberman 1997 Systemic chemotherapy for gastric carcinoma followed by postoperative intraperitoneal therapy: a final report Cancer. 79 1767 1775 9128994 10.1002/(SICI)1097-0142(19970501)79:9<1767::AID- CNCR19>3.0.CO;2-W 1:STN:280:DyaK2s3nsFWjsg%3D%3D
19. B Brenner MA Shah MS Karpeh M Gonen MF Brennan DG Coit DS Klimstra LH Tang DP Kelsen 2006 A phase II trial of neoadjuvant cisplatin-fluorouracil followed by postoperative intraperitoneal floxuridine-leucovorin in patients with locally advanced gastric cancer Ann Oncol. 17 1404 1411 16788003 10.1093/annonc/mdl133 1:STN:280:DC%2BD28nlt1yjtg%3D%3D
20. E Newman M Potmesil T Ryan S Marcus S Hiotis H Yee B Norwood M Wendell F Muggia H Hochster 2005 Neoadjuvant chemotherapy, surgery, and adjuvant intraperitoneal chemotherapy in patients with locally advanced gastric or gastroesophageal junction carcinoma: a phase II study Semin Oncol. 32 S97 S100 16399443 10.1053/j.seminoncol.2005.06.002
21. E Newman SG Marcus M Potmesil S Sewak H Yee J Sorich M Hayek F Muggia H Hochster 2002 Neoadjuvant chemotherapy with CPT-11 and cisplatin downstages locally advanced gastric cancer J Gastrointest Surg. 6 212 223 11992807 10.1016/S1091-255X(01)00054-3 discussion 223
22. FM Muggia KK Chan C Russell N Colombo JL Speyer K Sehgal S Jeffers J Sorich L Leichman U Beller, et al. 1991 Phase I and pharmacologic evaluation of intraperitoneal 5-fluoro-2′-deoxyuridine Cancer Chemother Pharmacol. 28 241 250 1831736 1:STN:280:DyaK3MzkslGjuw%3D%3D
23. JG Park JM Collins AF Gazdar CJ Allegra SM Steinberg RF Greene BS Kramer 1988 Enhancement of fluorinated pyrimidine-induced cytotoxicity by leucovorin in human colorectal carcinoma cell lines J Natl Cancer Inst. 80 1560 1564 2973527 10.1093/jnci/80.19.1560 1:CAS:528:DyaL1MXltVyqsQ%3D%3D
24. R Simon 1989 Optimal two-stage designs for phase II clinical trials Control Clin Trials. 10 1 10 2702835 10.1016/0197-2456(89)90015-9 1:STN:280:DyaL1M7ps1SjsQ%3D%3D
25. EL Kaplan P Meier 1958 Nonparametric estimation from incomplete observations J Am Stat Assoc 53 457 481 10.2307/2281868
26. Newman E, Hussain M, Muggia FM. Intraperitoneal drug therapy for intra-abdominal spread of cancer. In: Silberman H, Silberman AW (eds) Principles and practice of surgical oncology: multidisciplinary approach to difficult problems. Philadelphia: Lippincott Williams & Wilkins; 2010.
27. AA Garcia FM Muggia CP Spears S Jeffers H Silberman M Pujari RT Koda 2001 Phase I and pharmacologic study of i.v. hydroxyurea infusion given with i.p. 5-fluoro-2'-deoxyuridine and leucovorin Anticancer Drugs 12 505 511 11459996 10.1097/00001813-200107000-00003 1:CAS:528:DC%2BD3MXlvFersbw%3D
28. L Leichman H Silberman CG Leichman CP Spears M Ray FM Muggia M Kiyabu R Radin L Laine S Stain, et al. 1992 Preoperative systemic chemotherapy followed by adjuvant postoperative intraperitoneal therapy for gastric cancer: a University of Southern California pilot program J Clin Oncol. 10 1933 1942 1453207 1:STN:280:DyaK3s%2FosFeqtA%3D%3D
29. FM Muggia E LePoidevin S Jeffers C Russell W Boswell CP Morrow J Curtin J Schlaerth 1992 Intraperitoneal therapy for ovarian cancer: analysis of fluid distribution by computerized tomography Ann Oncol. 3 149 154 1606086 1:STN:280:DyaK383pslGgsg%3D%3D
30. VK Israel C Jiang FM Muggia A Tulpule S Jeffers L Leichman CP Morrow L Roman CG Leichman KK Chan 1995 Intraperitoneal 5-fluoro-2'-deoxyuridine (FUDR) and (S)-leucovorin for disease predominantly confined to the peritoneal cavity: a pharmacokinetic and toxicity study Cancer Chemother Pharmacol. 37 32 38 7497594 10.1007/BF00685626 1:CAS:528:DyaK28XlvFylsg%3D%3D
31. E Topuz M Basaran P Saip A Aydiner A Argon B Sakar F Tas K Uygun D Bugra NF Aykan 2002 Adjuvant intraperitoneal chemotherapy with cisplatinum, mitoxantrone, 5-fluorouracil, and calcium folinate in patients with gastric cancer: a phase II study Am J Clin Oncol. 25 619 624 12478012 10.1097/00000421-200212000-00019
32. W Yu I Whang A Averbach D Chang PH Sugarbaker 1998 Morbidity and mortality of early postoperative intraperitoneal chemotherapy as adjuvant therapy for gastric cancer Am Surg. 64 1104 1108 9798779 1:STN:280: DyaK1M%2FhtlWhsQ%3D%3D
33. HR Rosen G Jatzko S Repse S Potrc H Neudorfer P Sandbichler J Zacherl H Rabl P Holzberger P Lisborg M Czeijka 1998 Adjuvant intraperitoneal chemotherapy with carbon-adsorbed mitomycin in patients with gastric cancer: results of a randomized multicenter trial of the Austrian Working Group for Surgical Oncology J Clin Oncol. 16 2733 2738 9704725 1:CAS:528:DyaK1cXlsFCgu7w%3D
34. JH Cheong JY Shen CS Song WJ Hyung JG Shen SH Choi SH Noh 2007 Early postoperative intraperitoneal chemotherapy following cytoreductive surgery in patients with very advanced gastric cancer Ann Surg Oncol. 14 61 68 17058123 10.1245/s10434-006-9205-7
35. W Yu I Whang HY Chung A Averbach PH Sugarbaker 2001 Indications for early postoperative intraperitoneal chemotherapy of advanced gastric cancer: results of a prospective randomized trial World J Surg. 25 985 990 11571980 10.1007/s00268-001-0067-7 1:STN:280:DC%2BD3MrisVGmtw%3D%3D
36. Y Yonemura X de Aretxabala T Fujimura S Fushida K Katayama E Bandou K Sugiyama T Kawamura K Kinoshita Y Endou T Sasaki 2001 Intraoperative chemohyperthermic peritoneal perfusion as an adjuvant to gastric cancer: final results of a randomized controlled study Hepatogastroenterology. 48 1776 1782 11813623 1:STN:280:DC%2BD38%2Fos1eguw%3D%3D
37. S Fushida J Kinoshita Y Yagi H Funaki S Kinami I Ninomiya T Fujimura G Nishimura M Kayahara T Ohta 2008 Dual anti-cancer effects of weekly intraperitoneal docetaxel in treatment of advanced gastric cancer patients with peritoneal carcinomatosis: a feasibility and pharmacokinetic study Oncol Rep. 19 1305 1310 18425392 1:CAS:528:DC%2BD1cXmtFKqtrY%3D
38. Y Fujiwara T Nishida S Takiguchi K Nakajima H Miyata M Yamasaki K Yamamoto JH Moon M Mori Y Doki 2010 Feasibility study of S-1 and intraperitoneal docetaxel combination chemotherapy for gastric cancer with peritoneal dissemination Anticancer Res. 30 1335 1339 20530449 1:CAS:528: DC%2BC3cXovV2gtrk%3D
39. Combest AJ, Zorn KK, Edwards RP, Hanna SK, Habibi S, Strange M, Zamboni B, Krivak TC, Sukurmvanich P, Zamboni W. Pharmacokinetics (PK) of oxaliplatin (OX) after intraperitoneal (IP) and intravenous (IV) administration in patients with gynecological malignancies. Chicago: American Society of Clinical Oncology; 2010.
40. H Ishigami J Kitayama K Otani T Kamei D Soma H Miyato H Yamashita A Hidemura S Kaisaki H Nagawa 2009 Phase I pharmacokinetic study of weekly intravenous and intraperitoneal paclitaxel combined with S-1 for advanced gastric cancer Oncology. 76 311 314 19299904 10.1159/000209277 1:CAS:528:DC%2BD1MXltFWhurc%3D