PCR for the diagnosis of sepsis: Hope or hype?

Critical Care

Volumn 15, Issue 1, 2010, Pages

  Schrenzel, Jacques ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; BACTERIAL DNA; NUCLEIC ACID;

ANTIMICROBIAL THERAPY; BACTEREMIA; BACTERIAL DNAEMIA; COST EFFECTIVENESS ANALYSIS; ESCHERICHIA COLI; HUMAN; MATHEMATICAL MODEL; MICROORGANISM DETECTION; MOLECULAR DIAGNOSIS; NONHUMAN; NOTE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; SEPSIS;

EID: 84856614215     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc9378     Document Type: Note

References (5)

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2. Lehmann LE, Alvarez J, Hunfeld KP, Goglio A, Kost GJ, Louie RF, Raglio A, Regueiro BJ, Wissing H, Stuber F. Potential clinical utility of polymerase chain reaction in microbiological testing for sepsis. Crit Care Med 2009, 37:3085-3090. 10.1097/CCM.0b013e3181b033d7, 19633541.
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4. Kollef MH, Sherman G, Ward S, Fraser VJ. Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients. Chest 1999, 115:462-474. 10.1378/chest.115.2.462, 10027448.
5. Kumar A, Ellis P, Arabi Y, Roberts D, Light B, Parrillo JE, Dodek P, Wood G, Kumar A, Simon D, Peters C, Ahsan M, Chateau D. Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock. Chest 2009, 136:1237-1248. 10.1378/chest.09-0087, 19696123.