Dengue virus nonstructural protein NS1 binds to prothrombin/thrombin and inhibits prothrombin activation

Journal of Infection

Volumn 64, Issue 3, 2012, Pages 325-334

  Lin, Shi Wei ^a   Chuang, Yung Chun ^a   Lin, Yee Shin ^a   Lei, Huan Yao ^a   Liu, Hsiao Sheng ^a   Yeh, Trai Ming ^a  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

Author keywords

Coagulation; Dengue virus; Hemorrhage; Nonstructural protein; Prothrombin; Thrombin

Indexed keywords

NONSTRUCTURAL PROTEIN 1; PROTHROMBIN; RECOMBINANT PROTEIN; THROMBIN;

ARTICLE; BLOOD CLOTTING; COMPLEX FORMATION; CONTROLLED STUDY; DENGUE VIRUS; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOPRECIPITATION; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; THROMBOCYTE ACTIVATION; VIRUS ATTACHMENT;

AMINO ACID SEQUENCE; DENGUE; DENGUE HEMORRHAGIC FEVER; DENGUE VIRUS; ENZYME ACTIVATION; HUMANS; MOLECULAR SEQUENCE DATA; MULTIPROTEIN COMPLEXES; PARTIAL THROMBOPLASTIN TIME; PROTEIN BINDING; PROTHROMBIN; RECOMBINANT PROTEINS; THROMBIN; THROMBIN TIME; VIRAL NONSTRUCTURAL PROTEINS;

EID: 84856605644     PISSN: 01634453     EISSN: 15322742     Source Type: Journal    
DOI: 10.1016/j.jinf.2011.11.023     Document Type: Article

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