Development of RNA aptamer and its ligand binding assay on microchip electrophoresis

Current Chemical Genomics

Volumn 6, Issue 1, 2012, Pages 1-5

  Ohno, Ken Ichi ^a   Nakata, Chikara ^a   Sano, Yoshihiro ^a   Nishikawa, Fumiko ^b   Nishikawa, Satoshi ^b   Arakawa, Hidetoshi ^a  

^a SHOWA UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Aptamer; Conformational differences; Fluorescence detection; Intercalating dyes; Microchip electrophoresis; SELEX

Indexed keywords

APTAMER; GONADOTROPIN; INTERCALATING AGENT; OLIGONUCLEOTIDE; RNA APTAMER; SINGLE STRANDED RNA; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; BINDING AFFINITY; BINDING ASSAY; COMBINATORIAL CHEMISTRY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; FLUORESCENCE ANALYSIS; LIGAND BINDING; MICROCHIP ELECTROPHORESIS; MOLECULAR LIBRARY; PHASE SEPARATION; PREDICTION; PRIORITY JOURNAL; PROCESS DEVELOPMENT; RNA BINDING; RNA CONFORMATION; SENSITIVITY AND SPECIFICITY;

EID: 84856597900     PISSN: None     EISSN: 18753973     Source Type: Journal    
DOI: 10.2174/1875397301206010001     Document Type: Article

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