Differences in the peripheral immune response between lambs and adult ewes experimentally infected with Mycobacterium avium subspecies paratuberculosis

Veterinary Immunology and Immunopathology

Volumn 145, Issue 1-2, 2012, Pages 23-31

  Delgado, Laetitia ^a   Juste, Ramón A ^b   Muñoz, María ^a   Morales, Silvia ^a   Benavides, Julio ^a   Ferreras, M Carmen ^a   García Marín, J Francisco ^a   Pérez, Valentín ^a  

^a UNIVERSITY OF LEÓN   (Spain)

^b NEIKER and a Vaccine producing Commercial Company CZVSL   (Spain)

Author keywords

Age; ELISA; IFN ; Paratuberculosis; Sheep; Skin test

Indexed keywords

GAMMA INTERFERON;

ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE COURSE; EWE; HUMORAL IMMUNITY; IMMUNE RESPONSE; INNATE IMMUNITY; LAMB; NONHUMAN; PARATUBERCULOSIS; PATHOGENESIS; PERIPHERAL IMMUNE RESPONSE; POLYMERASE CHAIN REACTION; SKIN TEST;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; IMMUNITY, CELLULAR; IMMUNITY, HUMORAL; INTERFERON-GAMMA; MYCOBACTERIUM AVIUM SUBSP. PARATUBERCULOSIS; PARATUBERCULOSIS; POLYMERASE CHAIN REACTION; SHEEP; SHEEP DISEASES; SKIN TESTS;

ANIMALIA; AVES; CORYNEBACTERINEAE; MYCOBACTERIUM AVIUM; OVIS; OVIS ARIES;

EID: 84856531747     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2011.10.005     Document Type: Article

References (37)

1. Aduriz J.J., Juste R.A., Cortabarria N. Lack of mycobactin dependence of mycobacteria isolated on Middlebrook 7H11 from clinical cases of ovine paratuberculosis. Vet. Microbiol. 1995, 45:211-217.
2. Bull T.J., McMinn E.J., Sidi-Boumedine K., Skull A., Durkin D., Neild P., Rhodes G., Pickup R., Hermon-Taylor J. Detection and verification of Mycobacterium avium subsp. paratuberculosis in fresh ileocolonic mucosal biopsy specimens from individual with and without Crohn's disease. J. Clin. Microbiol. 2003, 41:2915-2923.
3. Clarke C.J. The pathology and pathogenesis of paratuberculosis in ruminants and other species. J. Comp. Pathol. 1997, 116:217-261.
4. Corpa J.M., Pérez V., García Marín J.F. Differences in the immune responses in lambs and kids vaccinated against paratuberculosis, according to the age of vaccination. Vet. Microbiol. 2000, 77:475-485.
5. De Silva K., Begg D., Carter N., Taylor D., Di Fiore L., Whittingtong R. The early lymphocyte proliferation response in sheep exposed to Mycobacterium avium subsp. paratuberculosis compared to infection status. Immunobiology 2010, 215:12-25.
6. Doyle T.M. Susceptibility to Johne's disease in relation to age. Vet. Rec. 1953, 65:363-365.
7. Eisenberg S.W., Nielen M., Santema W., Houwers D.J., Heederik D., Koets A.P. Detection of spatial and temporal spread of Mycobacterium avium subsp. paratuberculosis in the environment of a cattle farm through bio-aerosols. Vet. Microbiol. 2010, 143:284-292.
8. García Marín J.F., Tellechea J., Gutiérrez M., Pérez V., Juste R.A. Paratuberculosis vaccination in sheep modifies and limits the development of lesions. Proc. 5th Int. Coll. PTBC 1997, 223. IAP, Rehoboth, USA. R.J. Chiodini, M.E. Hines, M.T. Collins (Eds.).
9. Garrido J.M., Cortabarría N., Oguiza J.A., Adúriz G., Juste R.A. Use of a PCR method on fecal samples for diagnosis of sheep paratuberculosis. Vet. Microbiol. 2000, 77:379-386.
10. Geijo, M.V., 2007. Estudio de variables inmunológicas y bacteriológicas en relación con la inmunización frente a paratuberculosis en los rumiantes. Doctoral Thesis, University of León, Spain.
11. González J., Geijo M.V., García-Pariente C., Verna A., Corpa J.M., Reyes L.E., Ferreras M.C., Juste R.A., García Marín J.F., Pérez V. Histopathological classification of lesions associated with natural paratuberculosis infection in cattle. J. Comp. Pathol. 2005, 133:184-196.
12. Gutiérrez M., Tellechea J., García Marín J.F. Evaluation of cellular and serological diagnostic tests for the detection of Mycobacterium bovis-infected goats. Vet. Microbiol. 1998, 62:281-290.
13. Gwozdz J.M., Thompson K.G., Manktelow B.W., Murray A., West D.M. Vaccination against paratuberculosis of lambs already infected experimentally with Mycobacterium avium subspecies paratuberculosis. Aust. Vet. J. 2000, 78:560-566.
14. Hines M.E., Stabel R.J., Sweeney R.W., Griffin F., Talaat A.M., Bakker D., Benedictus G., Davis W.C., de Lisle G.W., Gardner I.A., Juste R.A., Kapur V., Koets A., McNair J., Pruitt G., Whitlock R.H. Experimental challenge models for Johne's disease: a review and proposed international guidelines. Vet. Microbiol. 2007, 122:197-222.
15. Hostetter J., Steadham E., Haynes J., Bailey T., Cheville N. Phagosomal maturation and intracellular survival of Mycobacterium avium subspecies paratuberculosis in J774 cells. Comp. Immunol. Microbiol. Infect. Dis. 2003, 26:269-283.
16. Juste R.A., García Marín J.F., Peris B., Sáez de Ocáriz C.S., Badiola J.J. Experimental infection of vaccinated and non-vaccinated lambs with Mycobacterium paratuberculosis. J. Comp. Pathol. 1994, 110:185-194.
17. Juste R.A., Elquezabal N., Pavón A., Garrido J.M., Geijo M., Sevilla I., Cabriada J.L., Tejada A., García-Campos F., Casado R., Ochotorena I., Izeta A. Association between Mycobacterium avium subsp. paratuberculosis DNA in blood and cellular and humoral immune response in inflammatory bowel disease patients and controls. Int. J. Infect. Dis. 2009, 13:247-254.
18. Kagina B.M., Abel B., Bowmaker M., Scriba T.J., Gelderbloem S., Smit E., Erasmus M., Nene N., Walzl G., Black G., Hussey G.D., Hesseling A.C., Hanekom W.A. Delaying BCG vaccination from birth to 10 weeks of age may result in an enhanced memory CD4 T cell response. Vaccine 2009, 27:5488-5495.
19. Larsen A.B., Merkal R.S., Cutlip R.C. Age of cattle as related to resistance to infection with Mycobacterium paratuberculosis. Am. J. Vet. Res. 1975, 36:255-257.
20. Mackintosh C.G., Labes R.E., Clark R.G., De Lisle G.W., Griffin J.F. Experimental infections in young red deer (Cervus elaphus) with a bovine and an ovine strain of Mycobacterium avium subsp paratuberculosis. N. Z. Vet. J. 2007, 55:23-29.
21. Mackintosh C.G., Clark R.G., Thompson B., Tolentino B., Griffin J.F., de Lisle G.W. Age susceptibility of red deer (Cervus elaphus) to paratuberculosis. Vet. Microbiol. 2010, 143:255-261.
22. Nisbet D.I., Gilmour N.J.L., Brotherston J.G. Quantitative studies of Mycobacterium johnei in tissues of sheep. III. Intestinal histopathology. J. Comp. Pathol. 1962, 72:80-91.
23. Olsen I., Boysen P., Kulberg S., Hope J.C., Jungersen G., Storset A.K. Bovine NK cells can produce gamma interferon in response to the secreted mycobacterial proteins ESAT-6 and MPP14 but not in response to MPB70. Infect. Immun. 2005, 73:5628-5635.
24. Payne J.M., Rankin J.D. A comparison of the pathogenesis of experimental Johne's disease in calves and cows. Res. Vet. Sci. 1961, 2:175-179.
25. Pérez V., García Marín J.F., Badiola J.J. Description and classification of different types of lesion associated with natural paratuberculosis infection in sheep. J. Comp. Pathol. 1996, 114:107-122.
26. Pérez V., Tellechea J., Badiola J.J., Gutiérrez M., García Marín J.F. Relation between serologic response and pathologic findings in sheep with naturally acquired paratuberculosis. Am. J. Vet. Res. 1997, 58:799-803.
27. Pérez V., Tellechea J., Corpa J.M., Gutiérrez M., García Marín J.F. Relation between pathologic findings and cellular immune responses in sheep with naturally acquired paratuberculosis. Am. J. Vet. Res. 1999, 60:123-127.
28. Rozen S., Skaletsky H. Primer3 on the WWW for general users and for biologist programmers. Bioinformatics Methods and Protocols: Methods in Molecular Biology 2000, 365-386. Humana Press, Totowa, USA, Source code available at. http://fokker.wi.mit.edu/primer3/, S. Krawetz, S. Misener (Eds.).
29. Ratnamohan T.N., Spencer T.L. A technique for the purification of Mycobacterium paratuberculosis from the ileal mucosa of infected cattle. Aust. Vet. J. 1986, 63:185-187.
30. Ryan T.J., Buddle B.M., de Lisle G.W. An evaluation of the gamma interferon test for detecting bovine tuberculosis in cattle 8 to 28 days after tuberculin skin testing. Res. Vet. Sci. 2000, 69:57-61.
31. Sevilla I., Singh S.V., Garrido J.M., Aduriz G., Rodríguez S., Geijo M.V., Whittington R.J., Saunders V., Whitlock R.H., Juste R.A. Molecular typing of Mycobacterium avium subspecies paratuberculosis strains from different hosts and regions. Rev. Sci. Tech. 2005, 24:1061-1066.
32. Stabel J.R. Host responses to Mycobacterium avium subsp. paratuberculosis: a complex arsenal. Anim. Health Res. Rev. 2006, 7:60-70.
33. Stabel J.R., Kimura K., Robbe-Austerman S. Augmentation of secreted and intracellular gamma interferon following johnin purified protein derivative sensitization of cows naturally infected with Mycobacterium avium subsp. paratuberculosis. J. Vet. Diagn. Invest. 2007, 19:43-51.
34. Sweeney R.W., Uzonna J., Whitlock R.H., Habecker P.L., Chilton P., Scott P. Tissue predilection sites and effect of dose on Mycobacterium avium subsp. paratuberculosis organism recovery in a short-term bovine experimental oral infection model. Res. Vet. Sci. 2006, 80:253-259.
35. Varges R., Marassi C.D., Oelemann W., Lilenbaum W. Interference of intradermal tuberculin tests on the serodiagnosis of paratuberculosis in cattle. Res. Vet. Sci. 2009, 86:371-372.
36. Windsor P., Whittington R.J. Evidence for age susceptibility to cattle to Johne's disease. Vet. J. 2010, 184:37-44.
37. Whipple D.L., Palmer M.V., Slaughter R.E., Jones S.L. Comparison of purified protein derivatives and effect of skin testing on results of a commercial gamma interferon assay for diagnosis of tuberculosis in cattle. J. Vet. Diagn. Invest. 2001, 13:117-122.