Augmented glutathione synthesis decreases acrolein toxicity

Biochemical and Biophysical Research Communications

Volumn 418, Issue 1, 2012, Pages 110-115

  Tomitori, Hideyuki ^a   Nakamura, Mizuho ^a   Sakamoto, Akihiko ^a   Terui, Yusuke ^a   Yoshida, Madoka ^b   Igarashi, Kazuei ^b   Kashiwagi, Keiko ^a  

^a CHIBA INSTITUTE OF SCIENCE   (Japan)

^b CHIBA UNIVERSITY   (Japan)

Author keywords

Acrolein toxicity decreasing cells; C Jun; Glutathione; JNK; NF B; Polyamines

Indexed keywords

ACROLEIN; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CARCINOMA CELL; CELL DAMAGE; CELL GROWTH; CELL ISOLATION; CONJUGATION; CYTOTOXICITY; DETOXIFICATION; ENZYME ACTIVATION; GENE EXPRESSION; GLUTATHIONE METABOLISM; IC 50; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

ACROLEIN; ANIMALS; BASE SEQUENCE; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL SEPARATION; EXONS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; INTRONS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MICE; MOLECULAR SEQUENCE DATA; NF-KAPPA B; OXIDATIVE STRESS; PHOSPHORYLATION;

EID: 84856501233     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2011.12.143     Document Type: Article

References (31)

1. Hensley K., Robinson K.A., Gabbita S.P., Salsman S., Floyd R.A. Reactive oxygen species, cell signaling, and cell injury. Free Radic. Biol. Med. 2000, 28:1456-1462.
2. Stevens J.F., Maier C.S. Acrolein: sources, metabolism, and biomolecular interactions relevant to human health and disease. Mol. Nutr. Food Res. 2008, 52:7-25.
3. Wang X., Michaelis E.K. Selective neuronal vulnerability to oxidative stress in the brain. Front. Aging Neurosci. 2010, 2:12.
4. Igarashi K., Kashiwagi K. Modulation of cellular function by polyamines. Int. J. Biochem. Cell Biol. 2010, 42:39-51.
5. Tomitori H., Usui T., Saeki N., Ueda S., Kase H., Nishimura K., Kashiwagi K., Igarashi K. Polyamine oxidase and acrolein as novel biochemical markers for diagnosis of cerebral stroke. Stroke 2005, 36:2609-2613.
6. Casero R.A., Pegg A.E. Polyamine catabolism and disease. Biochem. J. 2009, 421:323-338.
7. Igarashi K., Kashiwagi K. Protein-conjugated acrolein as a biochemical marker of brain infarction. Mol. Nutr. Food Res. 2011, 55:1332-1341.
8. Sharmin S., Sakata K., Kashiwagi K., Ueda S., Iwasaki S., Shirahata A., Igarashi K. Polyamine cytotoxicity in the presence of bovine serum amine oxidase. Biochem. Biophys. Res. Commun. 2001, 282:228-235.
9. Yoshida M., Tomitori H., Machi Y., Hagihara M., Higashi K., Goda H., Ohya T., Niitsu M., Kashiwagi K., Igarashi K. Acrolein toxicity: comparison with reactive oxygen species. Biochem. Biophys. Res. Commun. 2009, 378:313-318.
10. Bradley M.A., Markesbery W.R., Lovell M.A. Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease. Free Radic. Biol. Med. 2010, 48:1570-1576.
11. Sakata K., Kashiwagi K., Sharmin S., Ueda S., Irie Y., Murotani N., Igarashi K. Increase in putrescine, amine oxidase, and acrolein in plasma of renal failure patients. Biochem. Biophys. Res. Commun. 2003, 305:143-149.
12. Igarashi K., Ueda S., Yoshida K., Kashiwagi K. Polyamines in renal failure. Amino Acids 2006, 31:477-483.
13. Saiki R., Nishimura K., Ishii I., Omura T., Okuyama S., Kashiwagi K., Igarashi K. Intense correlation between brain infarction and protein-conjugated acrolein. Stroke 2009, 40:3356-3361.
14. Saiki R., Park H., Ishii I., Yoshida M., Nishimura K., Toida T., Tatsukawa H., Kojima S., Ikeguchi Y., Pegg A.E., Kashiwagi K., Igarashi K. Brain infarction correlates more closely with acrolein than with reactive oxygen species. Biochem. Biophys. Res. Commun. 2011, 404:1044-1049.
15. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 1976, 72:248-254.
16. Fujii S., Hitomi Y. New synthetic inhibitors of C1r, C1 esterase, thrombin, plasmin, kallikrein and trypsin. Biochim. Biophys. Acta 1981, 661:342-345.
17. Nielsen P.J., Manchester K.L., Towbin H., Gordon J., Thomas G. The phosphorylation of ribosomal protein S6 in rat tissues following cycloheximide injection, in diabetes, and after denervation of diaphragm. A simple immunological determination of the extent of S6 phosphorylation on protein blots. J. Biol. Chem. 1982, 257:12316-12321.
18. Uchida K., Kanematsu M., Morimitsu Y., Osawa T., Noguchi N., Niki E. Acrolein is a product of lipid peroxidation reaction. Formation of free acrolein and its conjugate with lysine residues in oxidized low density lipoproteins. J. Biol. Chem. 1998, 273:16058-16066.
19. J. Sambrook, E.F. Fritsch, T. Maniatis, Extraction, purification, and analysis of mRNA from eukaryotic cells. in: J. Sambrook, D.W. Russell, (Eds.), Molecular Cloning: A Laboratory Manual, 3rd ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA, 2001 (Chapter 7).
20. Isegawa Y., Sheng J., Sokawa Y., Yamanishi K., Nakagomi O., Ueda S. Selective amplification of cDNA sequence from total RNA by cassette-ligation mediated polymerase chain reaction (PCR): application to sequencing 6.5kb genome segment of hantavirus strain B-1. Mol. Cell. Probes 1992, 6:467-475.
21. Krejsa C.M., Franklin C.C., White C.C., Ledbetter J.A., Schieven G.L., Kavanagh T.J. Rapid activation of glutamate cysteine ligase following oxidative stress. J. Biol. Chem. 2010, 285:16116-16124.
22. Raftos J.E., Whillier S., Kuchel P.W. Glutathione synthesis and turnover in the human erythrocyte: alignment of a model based on detailed enzyme kinetics with experimental data. J. Biol. Chem. 2010, 285:23557-23567.
23. Smeal T., Binetruy B., Mercola D.A., Birrer M., Karin M. Oncogenic and transcriptional cooperation with Ha-Ras requires phosphorylation of c-Jun on serines 63 and 73. Nature 1991, 354:494-496.
24. Naumann M., Scheidereit C. Activation of NF-κB in vivo is regulated by multiple phosphorylations. EMBO J. 1994, 13:4597-4607.
25. Spiegelman V.S., Stavropoulos P., Latres E., Pagano M., Ronai Z., Slaga T.J., Fuchs S.Y. Induction of β-transducin repeat-containing protein by JNK signaling and its role in the activation of NF-κB. J. Biol. Chem. 2001, 276:27152-27158.
26. Biswal S., Acquaah-Mensah G., Datta K., Wu X., Kehrer J.P. Inhibition of cell proliferation and AP-1 activity by acrolein in human A549 lung adenocarcinoma cells due to thiol imbalance and covalent modifications. Chem. Res. Toxicol. 2002, 15:180-186.
27. Finkelstein E.I., Ruben J., Koot C.W., Hristova M., van der Vliet A. Regulation of constitutive neutrophil apoptosis by the α, β-unsaturated aldehydes acrolein and 4-hydroxynonenal. Am. J. Physiol. Lung Cell. Mol. Physiol. 2005, 289:L1019-1028.
28. Yoshida M., Tomitori H., Machi Y., Katagiri D., Ueda S., Horiguchi K., Kobayashi E., Saeki N., Nishimura K., Ishii I., Kashiwagi K., Igarashi K. Acrolein, IL-6 and CRP as markers of silent brain infarction. Atherosclerosis 2009, 203:557-562.
29. Yoshida M., Higashi K., Kobayashi E., Saeki N., Wakui K., Kusaka T., Takizawa H., Kashiwado K., Suzuki N., Fukuda K., Nakamura T., Watanabe S., Tada K., Machi Y., Mizoi M., Toida T., Kanzaki T., Tomitori H., Kashiwagi K., Igarashi K. Correlation between images of silent brain infarction, carotid atherosclerosis and white matter hyperintensity, and plasma levels of acrolein, IL-6 and CRP. Atherosclerosis 2010, 211:475-479.
30. Higashi K., Yoshida M., Igarashi A., Ito K., Wada Y., Murakami S., Kobayashi D., Nakano M., Sohda M., Nakajima T., Narita I., Toida T., Kashiwagi K., Igarashi K. Intense correlation between protein-conjugated acrolein and primary Sjogren's syndrome. Clin. Chim. Acta 2010, 411:359-363.
31. Hamann K., Shi R. Acrolein scavenging: a potential novel mechanism of attenuating oxidative stress following spinal cord injury. J. Neurochem. 2009, 111:1348-1356.