Diazinon-induced brain toxicity and protection by vitamins e plus C

Toxicology and Industrial Health

Volumn 28, Issue 1, 2012, Pages 51-57

  Yilmaz, Nigar ^a   Yilmaz, Mustafa ^b   Altuntas, Irfan ^c  

^a MUSTAFA KEMAL UNIVERSITY   (Turkey)

^b ANTAKYA STATE HOSPITAL   (Turkey)

^c SULEYMAN DEMIREL UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

antioxidant status; brain; Diazinon; lipid peroxidation; vitamin C; vitamin E

Indexed keywords

ALPHA TOCOPHEROL; ASCORBIC ACID; CATALASE; DIMPYLATE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; NEUROPROTECTIVE AGENT; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN LEVEL; BRAIN PROTECTION; BRAIN TOXICITY; CONTROLLED STUDY; ENZYME ACTIVITY; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; TREATMENT OUTCOME;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; BRAIN; BRAIN CHEMISTRY; CATALASE; DIAZINON; GLUTATHIONE PEROXIDASE; LIPID PEROXIDATION; MALE; MALONDIALDEHYDE; NEUROPROTECTIVE AGENTS; RATS; RATS, WISTAR; STATISTICS, NONPARAMETRIC; SUPEROXIDE DISMUTASE; VITAMIN E;

RATTUS;

EID: 84856477416     PISSN: 07482337     EISSN: 14770393     Source Type: Journal    
DOI: 10.1177/0748233711404035     Document Type: Article

References (30)

1. Abdollahi M, Mostafalou S, et al. Oxidative stress and cholinesterase inhibition in saliva and plasma of rats following subchronic exposure to malathion. Comparative Biochemistry and Physiology Part C: Toxicology and Pharmacology. 2004 ; 137 (1). 29-34 (Pubitemid 38230919)
2. Aebi H. Catalase in vitro. Methods in Enzymology. 1984 ; 105: 121-126
3. Ahmed RS, Seth V, et al. Influence of dietary ginger (Zingiber officinales Rosc) on oxidative stress induced by malathion in rats. Food Chemistry and Toxicology. 2000 ; 38 (5). 443-450 (Pubitemid 30179734)
4. Akturk O, Demirin H, et al. The effects of diazinon on lipid peroxidation and antioxidant enzymes in rat heart and ameliorating role of vitamin E and vitamin C. Cell Biology and Toxicology. 2006 ; 22 (6). 455-461 (Pubitemid 44484489)
5. Altuntas I, Delibas N, et al. The effects of organophosphate insecticide methidathion on lipid peroxidation and anti-oxidant enzymes in rat erythrocytes: role of vitamins E and C. Human and Experimental Toxicology. 2002 ; 21 (12). 681-685 (Pubitemid 36124501)
6. Altuntas I, Kilinc I, et al. The effects of diazinon on lipid peroxidation and antioxidant enzymes in erythrocytes in vitro. Human and Experimental Toxicology. 2004 ; 23 (1). 9-13 (Pubitemid 38263152)
7. Appenroth D, Frob S, et al. Protective effects of vitamin E and C on cisplatin nephrotoxicity in developing rats. Archives of Toxicology. 1997 ; 71 (11). 677-683 (Pubitemid 27427514)
8. Bagchi D, Bagchi M, et al. In vitro and in vivo generation of reactive oxygen species, DNA damage and lactate dehydrogenase leakage by selected pesticides. Toxicology. 1995 ; 104 ((1-3)). 129-140 (Pubitemid 26016384)
9. Beyer WF, Fridovich I. Phosphate, not superoxide dismutase, facilitates electron transfer from ferrous salts to cytochrome c. Archives of Biochemistry and Biophysics. 1991 ; 285 (1). 60-63
10. Datta C, Gupta J, et al. Effects of organophosphorus insecticide phosphomidon on antioxidant defence components of human erythrocyte and plasma. Indian Journal of Experimental Biology. 1992 ; 30 (1). 65-67
11. Davitashvili DT, Museridze DP, et al. Correction of oxidative stress in the rat brain cortical cellular culture with vitamines E and C. Georgian Medical News. 2010 ; 180: 56-60
12. Fadillioglu E, Oztas E, et al. Protective effects of caffeic acid phenethyl ester on doxorubicin-induced cardiotoxicity in rats. Journal of Applied Toxicology. 2004 ; 24 (1). 47-52 (Pubitemid 38181541)
13. Frei B, England L, et al. Ascorbate is an outstanding antioxidant in human blood plasma. Proceedings of the National Academy of Sciences of the United States of America. 1989 ; 86 (16). 6377-6381 (Pubitemid 19210655)
14. Fridovich I. Biological effects of the superoxide radical. Archives of Biochemisrty and Biophysics. 1986 ; 247 (1). 1-11 (Pubitemid 16076916)
15. Gultekin F, Delibas N, et al. In vivo changes in antioxidant systems and protective role of melatonin and a combination of vitamin C and vitamin E on oxidative damage in erythrocytes induced by chlorpyrifos-ethyl in rats. Archives of Toxicology. 2001 ; 75 (2). 88-96 (Pubitemid 32304541)
16. Gultekin F, Ozturk M, et al. The effect of organophosphate insecticide chlorpyrifos-ethyl on lipid peroxidation and antioxidant enzymes (in vitro). Archives of Toxicology. 2000 ; 74 (9). 533-538
17. Halliwell B. Oxidative stress and neurodegeneration: where are we now?. Journal of Neurochemistry. 2006 ; 97 (6). 1634-1658 (Pubitemid 43873658)
18. Horton AA, Fairhurst S. Lipid peroxidation and mechanisms of toxicity. Critical Reviews in Toxicology. 1987 ; 18 (1). 27-79 (Pubitemid 17130738)
19. Jain SK. Hyperglycemia can cause membrane lipid peroxidation and osmotic fragility in human red blood cells. Journal of Biological Chemistry. 1989 ; 264 (35). 21340-21345 (Pubitemid 20017957)
20. John S, Kale M, et al. Protective effect of vitamin E in dimethoate and malathion induced oxidative stress in rat erythrocytes. Journal of Nutritional Biochemistry. 2001 ; 12 (9). 500-504 (Pubitemid 32785651)
21. Kannan K, Jain SK. Oxidative stress and apoptosis. Pathophysiology. 2000 ; 7 (3). 153-163
22. Kovacic P, Somanathan R. Ototoxicity and noise trauma: electron transfer, reactive oxygen species, cell signaling, electrical effects, and protection by antioxidants: practical medical aspects. Medicinal Hypotheses. 2008 ; 70 (5). 914-923 (Pubitemid 351400702)
23. Lowry OH, Rosebrough NJ, et al. Protein measurement with the Folin phenol reagent. Journal of Biological Chemistry. 1951 ; 193 (1). 265-275
24. Mateos R, Lecumberri E, et al. Determination of malondialdehyde (MDA) by high-performance liquid chromatography in serum and liver as a biomarker for oxidative stress. Application to a rat model for hypercholesterolemia and evaluation of the effect of diets rich in phenolic antioxidants from fruits. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 2005 ; 827 (1). 76-82 (Pubitemid 41551599)
25. Romeo C, Antonuccio P, et al. Raxofelast, a hydrophilic vitamin E-like antioxidant, reduces testicular ischemia-reperfusion injury. Urological Research. 2004 ; 32 (5). 367-371 (Pubitemid 39517962)
26. Shah MD, Iqbal M. Diazinon-induced oxidative stress and renal dysfunction in rats. Food Chemistry and Toxicology. 2010 ; 48 (12). 3345-3353
27. Stoyanovsky DA, Goldman R, et al. Endogenous ascorbate regenerates vitamin E in the retina directly and in combination with exogenous dihydrolipoic acid. Current Eye Research. 1995 ; 14 (3). 181-189
28. Tousoulis D, Antoniades C, et al. Effects of combined administration of vitamins C and E on reactive hyperemia and inflammatory process in chronic smokers. Atherosclerosis. 2003 ; 170 (2). 261-267 (Pubitemid 37377798)
29. Woolliams JA, Wiener G, et al. Variation in the activities of glutathione peroxidase and superoxide dismutase and in the concentration of copper in the blood in various breed crosses of sheep. Research in Veterinary Science. 1983 ; 34 (3). 253-256 (Pubitemid 13070011)
30. Zingg JM, Azzi A. Non-antioxidant activities of vitamin E. Current Medicinal Chemistry. 2004 ; 11 (9). 1113-1133 (Pubitemid 38585057)