COMT haplotype analyses in Malaysians with schizophrenia

Psychiatry Research

Volumn 195, Issue 1-2, 2012, Pages 83-84

  Tee, Shiau Foon ^a   Tang, Pek Yee ^b   Loh, Han Chern ^a  

^a UNIVERSITI TUNKU ABDUL RAHMAN   (Malaysia)

^b UTAR   (Malaysia)

Author keywords

Association study; Cathechol O methyltransferase; Haplotype; Schizophrenia

Indexed keywords

CATECHOL METHYLTRANSFERASE;

ADULT; ARTICLE; CASE CONTROL STUDY; COMT GENE; CONTROLLED STUDY; ETHNIC GROUP; FEMALE; GENE; GENETIC ASSOCIATION; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; MALAYSIAN; MALE; PRIORITY JOURNAL; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM;

ADOLESCENT; ADULT; CATECHOL O-METHYLTRANSFERASE; CHI-SQUARE DISTRIBUTION; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALAYSIA; MALE; POLYMORPHISM, SINGLE NUCLEOTIDE; PSYCHIATRIC STATUS RATING SCALES; SCHIZOPHRENIA; YOUNG ADULT;

EID: 84856460692     PISSN: 01651781     EISSN: 18727123     Source Type: Journal    
DOI: 10.1016/j.psychres.2011.07.039     Document Type: Article

References (12)

1. Barrett J.C., Fry B., Maller J., Daly M.J. Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics 2005, 21:263-265.
2. Chen J., Lipska B.K., Halim N., Ma Q.D., Matsumoto M., Melhem S., Kolachana B.S., Hyde T.M., Herman M.M., Apud J., Egan M.F., Kleinman J.E., Weinberger D.R. Functional analysis of genetic variation in catechol-omethyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain. The American Journal of Human Genetics 2004, 75:807-821.
3. Chien Y., Liu C., Fann C.S., Liu Y., Hwu H. Association of the 3' region of COMT with schizophrenia in Taiwan. Journal of the Formosan Medical Association 2009, 108:301-309.
4. Garriock H.A., Delgado P., Kling M.A., Carpenter L.L., Burke M., Burke W.J., Schwartz T., Marangell L.B., Husain M., Erickson R.P., Moreno Number of risk genotypes is a risk factor for major depressive disorder: a case control study. Behavioral and Brain Functions 2006, 2(Suppl. 1):24.
5. Harrison P.J., Weinberger D.R. Schizophrenia genes, gene expression and neuropathology: on the matter of their convergence. Molecular Psychiatry 2005, 10:40-68.
6. Kunugi H., Nanko S., Ueki A., Otsuka E., Hattori M., Hoda F., Vallada H.P., Arranz M.J., Collier D.A. High and low activity alleles of catechol-Omethyltransferase gene: ethnic difference and possible association with Parkinson's disease. Neuroscience Letters 1997, 221:202-204.
7. Molero P., Ortuño F., Zalacain M., Patiño-García A. Clinical involvement of catechol-O-methyltransferase polymorphisms in schizophrenia spectrum disorders: influence on the severity of psychotic symptoms and on the response to neuroleptic treatment. The Pharmacogenomics Journal 2007, 7:418-426.
8. Mukherjee N., Kidd K.K., Pakstis A.J., Speed W.C., Li H., Tarnok Z., Barta C., Kajuna S.L.B., Kidd J.R. The complex global pattern of genetic variation and linkage disequilibrium at catechol-O-methyltransferase. Molecular Psychiatry 2009, 15:216-225.
9. Pal P., Mihanović M., Molnar S., Xi H., Sun G., Guha S., Jeran N., Tomljenović A., Malna A., Misson S., Deka R., Rudan P. Association of tagging single nucleotide polymorphisms on 8 candidate genes in dopaminergic pathway with schizophrenia in Croatian population. Croatian Medical Journal 2009, 50:361-369.
10. Savitz J., Solms M., Ramesar R. The molecular genetics of cognition: dopamine, COMT and BDNF. Genes, Brain, and Behavior 2006, 5:311-328.
11. Shifman S., Bronstein M., Sternfeld M., Pisante-Shalom A., Lev-Lehman E., Weizman A., Reznik I., Spivak B., Grisaru N., Karp L., Schiffer R., Kotler M., Strous R.D., Swartz-Vanetik M., Knobler H.Y., Shinar E., Beckmann J.S., Yakir B., Risch N., Zak N.B., Darvasi A. A highly significant association between a COMT haplotype and schizophrenia. The American Journal of Human Genetics 2002, 71:1296-1302.
12. Zhang K.J., Gao J.J., An C.Y., Gao X.C., Zheng Z.J., Li R.L., Chen C. An association study between cathechol-O-methyltransferase gene and mental retardation in the Chinese Han population. Neuroscience Letters 2007, 419:83-87.