Appendicitis in paediatric age group: Correlation between preoperative inflammatory markers and postoperative histological diagnosis

African Journal of Paediatric Surgery

Volumn 8, Issue 3, 2011, Pages 309-312

  Mekhail, Peter ^a   Naguib, Nader ^a,b,c   Yanni, Fady ^c   Izzidien, Asal ^b  

^a UNIVERSITY HOSPITAL AINTREE   (United Kingdom)

^b PRINCE CHARLES HOSPITAL   (United Kingdom)

^c PILGRIM HOSPITAL   (United Kingdom)

Author keywords

Appendicitis; C reactive protein; inflammatory markers; paediatrics; white blood cell count

Indexed keywords

C REACTIVE PROTEIN;

APPENDICITIS; ARTICLE; CHILD; FEMALE; HUMAN; LEUKOCYTE COUNT; MALE; PATHOLOGY; PREDICTIVE VALUE; PREOPERATIVE PERIOD; PRESCHOOL CHILD; RETROSPECTIVE STUDY;

APPENDICITIS; C-REACTIVE PROTEIN; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; LEUKOCYTE COUNT; MALE; PREDICTIVE VALUE OF TESTS; PREOPERATIVE PERIOD; RETROSPECTIVE STUDIES;

EID: 84856450412     PISSN: 01896725     EISSN: 09745998     Source Type: Journal    
DOI: 10.4103/0189-6725.91676     Document Type: Article

References (27)

1. Stefanutti G, Ghirardo V, Gamba P. Inflammatory markers for acute appendicitis in children: Are they helpful? J Pediatr Surg 2007;42:773-6.
2. Addiss DG, Shaffer N, Fowler BS, Tauxe RV. The epidemiology ofappendicitis and appendectomy in the United States. Am J Epidemiol 1990;132:910-25.
3. O'Toole SJ, Karamanoukian HL, Allen JE, Caty MG, O'Toole D, Azizkhan RG, et al. Insurance-related differences in the presentation of pediatric appendicitis. J Pediatr Surg 1996;31:1032-4.
4. Gamal R, Moore TC. Appendicitits in children aged 13 years and younger. Am J Surg 1990;159:589-92.
5. Pearl RH, Hale DA, Molloy M, Schutt DC, Jaques DP. Paediatric appendicectomy. J Pediatr Surg 1995;30:173-8.
6. Flum DR, Morris A, Koepsell T, Dellinger EP. Has misdiagnosis of appendicitis decreased over time? A population-based analysis. JAMA 2001;286:1748-53.
7. Warner BW. Diagnosing appendicitis in children: It comes down to the physical examination. Gastroenterology 2004;127:675-7.
8. Sivit CJ. Controversies in emergency radiology: Acute appendicitis in children-the case for CT. Emerg Radiol 2004;10:238-40.
9. Kosloske AM, Love CL, Rohrer JE, Goldthorn JF, Lacey SR. The Diagnosis of Appendicitis in Children: Outcomes of a Strategy Based on Pediatric Surgical Evaluation. Pediatrics 2004;113;29-34.
10. Gronroos JM. Do normal leukocyte count and C-reactive protein value exclude acute appendicitis in children? Acta Paediatr 2001;90:649-51.
11. Dalal I, Somekh E, Bilker-Reich A, Boaz M, Gorenstein A, Serour F. Serum and peritoneal inflammatory mediators in children with suspected acute appendicitis. Arch Surg 2005;140:169-73.
12. Gronroos JM, Gronroos P. Leukocyte count and C-reactive protein in the diagnosis of acute appendicitis. Br J Surg 1999;86:501-4.
13. Yang HR, Wang YC, Chung PK, Chen WK, Jeng LB, Chen RJ. Laboratory tests in patients with acute appendicitis. ANZ J Surg 2006;76:71-4.
14. Andersson RE. Meta-analysis of the clinical and laboratory diagnosis of appendicitis. Br J Surg 2004;91:28-37.
15. Asfar S, Safar H, Khoursheed M, Dashti H, al-Bader A. Would measurement of C-reactive protein reduce the rate of negative exploration for acute appendicitis? J R Coll Surg Edinb 2000;45:21-4.
16. Lycopoulou L, Mamoulakis C, Hantzi E, Demetriadis D, Antypas S, Giannaki M, et al. Serum amyloid A protein levels as a possible aid in the diagnosis of acute appendicitis in children. Clin Chem Lab Med 2005;43:49-53.
17. Gronroos JM, Forsstrom JJ, Irjala K, Nevalainen TJ. Phospholipase A2, C-reactive protein, and white blood cell count in the diagnosis of acute appendicitis. Clin Chem 1994;40:1757-60.
18. Eriksson S, Granstrom L, Olander B, Pira U. Leukocyte elastase as a marker in the diagnosis of acute appendicitis. Eur J Surg 1995;161:901-5.
19. Wade DS, Marrow SE, Balsara ZN, Burkhard TK, Goff WB. Accuracy of ultrasound in the diagnosis of acute appendicitis compared with the surgeon's clinical impression. Arch Surg 1993;128:1039-46.
20. Wilson DH, Wilson PD, Walmsley RG, Horrocks JC, De Dombal FT. Diagnosis of acute abdominal pain in the accident and emergency department. Br J Surg 1977;64:250-4.
21. Bergeron E, Richer B, Gharib R, Giard A. Appendicitis is a place for clinical judgement. Am J Surg 1999;177:460-2.
22. Styrud J, Eriksson S, Segelman J, Granström L. Diagnostic accuracy in 2,351 patients undergoing appendicectomy for suspected acute appendicitis: A retrospective study 1986-1993. Dig Surg 1999;16:39-44.
23. Saidi RF, Ghasemi M. Role of Alvarado score in diagnosis and treatment of suspected acute appendicitis. Am J Emerg Med 2000;18:230-1.
24. Chung JL, Kong MS, Lin SL, Lin TY, Huang CS, Lou CC, et al. Diagnostic value of C-reactive protein in children with perforated appendicitis. Eur J Pediatr 1996;155:529-31.
25. Hallan S, Asberg A, Edna TH. Additional value of biochemical tests in suspected acute appendicitis. Eur J Surg 1997;163:533-8.
26. Paajanen H, Mansikka A, Laato M, Kettunen J, Kostiainen S. Are serum inflammatory markers age dependent in acute appendicitis? J Am Coll Surg 1997;184:303-8.
27. Sack U, Biereder B, Elouahidi T, Bauer K, Keller t, Tröbs RB. Diagnostic Value of Blood Inflammatory Markers for Detection of Acute Appendicitis in Children. BMC Surg 2006;6:15.