Staphylococcal-derived superantigen enhances peanut induced Th2 responses in the skin

Clinical and Experimental Allergy

Volumn 42, Issue 2, 2012, Pages 305-314

  Forbes Blom, E ^a   Camberis, M ^a   Prout, M ^a   Tang, S C ^a   Le Gros, G ^a  

^a MALAGHAN INSTITUTE OF MEDICAL RESEARCH   (New Zealand)

Author keywords

Food allergy; Peanut; SEB; Skin sensitization; Superantigen; Th2 response

Indexed keywords

ENDOTOXIN; FOOD ALLERGEN; INTERLEUKIN 4; PEANUT EXTRACT; SUPERANTIGEN; T LYMPHOCYTE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL COUNT; DISEASE PREDISPOSITION; FEMALE; FOOD ALLERGY; LYMPH NODE; MALE; MOUSE; NONHUMAN; PEANUT; PHENOTYPE; PRIORITY JOURNAL; RECEPTOR BINDING; STAPHYLOCOCCUS; TH2 CELL;

ALLERGENS; ANIMALS; ENTEROTOXINS; INTERLEUKIN-4; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; PEANUT HYPERSENSITIVITY; RECEPTORS, ANTIGEN, T-CELL; SKIN; STAPHYLOCOCCUS AUREUS; SUPERANTIGENS; TH2 CELLS;

EID: 84856446030     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2011.03861.x     Document Type: Article

References (47)

1. Breuer K, HAussler S, Kapp A, Werfel T. Staphylococcus aureus: colonizing features and influence of an antibacterial treatment in adults with atopic dermatitis. Br J Dermatol 2002; 147:55-61.
2. Breuer K, Wittmann M, Bosche B, Kapp A, Werfel T. Severe atopic dermatitis is associated with sensitization to staphylococcal enterotoxin B (SEB). Allergy 2000; 55:551-5.
3. Leung DY, Harbeck R, Bina P et al. Presence of IgE antibodies to staphylococcal exotoxins on the skin of patients with atopic dermatitis. Evidence for a new group of allergens. J Clin Invest 1993; 92:1374-80.
4. Akdis M, Simon HU, Weigl L, Kreyden O, Blaser K, Akdis CA. Skin homing (cutaneous lymphocyte-associated antigen-positive) CD8 + T cells respond to superantigen and contribute to eosinophilia and IgE production in atopic dermatitis. J Immunol 1999; 163:466-75.
5. Leung DY, Travers JB, Norris DA. The role of superantigens in skin disease. J Invest Dermatol 1995; 105(1 Suppl.):37S-42S.
6. Yawalkar N, Uguccioni M, Scharer J et al. Enhanced expression of eotaxin and CCR3 in atopic dermatitis. J Invest Dermatol 1999; 113:43-8.
7. Hong SC, Waterbury G, Janeway CA Jr. Different superantigens interact with distinct sites in the Vbeta domain of a single T cell receptor. J Exp Med 1996; 183:1437-46.
8. Janeway CA Jr. Selective elements for the V beta region of the T cell receptor: Mls and the bacterial toxic mitogens. Adv Immunol 1991; 50:1-53.
9. Yagi J, Baron J, Buxser S, Janeway CA Jr. Bacterial proteins that mediate the association of a defined subset of T cell receptor:CD4 complexes with class II MHC. J Immunol 1990; 144:892-901.
10. Hu-Li J, Pannetier C, Guo L et al. Regulation of expression of IL-4 alleles: analysis using a chimeric GFP/IL-4 gene. Immunity 2001; 14:1-11.
11. Min B, Prout M, Hu-Li J et al. Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite. J Exp Med 2004; 200:507-17.
12. Laouini D, Kawamoto S, Yalcindag A et al. Epicutaneous sensitization with superantigen induces allergic skin inflammation. J Allergy Clin Immunol 2003; 112:981-7.
13. Spergel JM, Mizoguchi E, Brewer JP, Martin TR, Bhan AK, Geha RS. Epicutaneous sensitization with protein antigen induces localized allergic dermatitis and hyperresponsiveness to methacholine after single exposure to aerosolized antigen in mice. J Clin Invest 1998; 101:1614-22.
14. Noh G, Jin H, Lee J, Noh J, Lee WM, Lee S. Eosinophilia as a predictor of food allergy in atopic dermatitis. Allergy Asthma Proc 2010; 31:e18-24.
15. Chen C-C, Grimbaldeston MA, Tsai M, Weissman IL, Galli SJ. Identification of mast cell progenitors in adult mice. Proc Natl Acad Sci USA 2005; 102:11408-13.
16. Ganeshan K, Neilsen CV, Hadsaitong A, Schleimer RP, Luo X, Bryce PJ. Impairing oral tolerance promotes allergy and anaphylaxis: a new murine food allergy model. J Allergy Clin Immunol 2009; 123:231-8.
17. Brandt EB, Strait RT, Hershko D et al. Mast cells are required for experimental oral allergen-induced diarrhea. J Clin Invest 2003; 112:1666-77.
18. Morafo V, Srivastava K, Huang CK et al. Genetic susceptibility to food allergy is linked to differential TH2-TH1 responses in C3H/HeJ and BALB/c mice. J Allergy Clin Immunol 2003; 111:1122-8.
19. Eisenbarth SC, Piggott DA, Huleatt JW, Visintin I, Herrick CA, Bottomly K. Lipopolysaccharide-enhanced, toll-like receptor 4-dependent T helper cell type 2 responses to inhaled antigen. J Exp Med 2002; 196:1645-51.
20. Eisenbarth SC, Zhadkevich A, Ranney P, Herrick CA, Bottomly K. IL-4-dependent Th2 collateral priming to inhaled antigens independent of Toll-like receptor 4 and myeloid differentiation factor 88. J Immunol 2004; 172:4527-34.
21. Gonzalo JA, Baixeras E, Gonzalez-Garcia A et al. Differential in vivo effects of a superantigen and an antibody targeted to the same T cell receptor. Activation-induced cell death vs passive macrophage-dependent deletion. J Immunol 1994; 152:1597-608.
22. Renz H, Bradley KL, Marrack P, Gelfand EW. T cells expressing variable elements of T-cell receptor beta 8 and beta 2 chain regulate murine IgE production. Proc Natl Acad Sci USA 1992; 89:6438-42.
23. Yang PC, Xing Z, Berin CM et al. TIM-4 expressed by mucosal dendritic cells plays a critical role in food antigen-specific Th2 differentiation and intestinal allergy. Gastroenterology 2007; 133:1522-33.
24. Fox A, Sasieni P, du Toit G, Syed H, Lack G. Household peanut consumption as a risk factor for the development of peanut allergy. J Allergy Clin Immunol 2009; 123:417-23.
25. Lack G. Epidemiologic risks for food allergy. J Allergy Clin Immunol 2008; 121:1331-6.
26. Lack G, Fox D, Northstone K, Golding J. Factors associated with the development of peanut allergy in childhood. N Engl J Med 2003; 348:977-85.
27. Parvataneni S, Gonipeta B, Tempelman RJ, Gangur V. Development of an adjuvant-free cashew nut allergy mouse model. Int Arch Allergy Immunol 2009; 149:299-304.
28. Strid J, Hourihane J, Kimber I, Callard R, Strobel S. Disruption of the stratum corneum allows potent epicutaneous immunization with protein antigens resulting in a dominant systemic Th2 response. Eur J Immunol 2004; 34:2100-9.
29. Strid J, Hourihane J, Kimber I, Callard R, Strobel S. Epicutaneous exposure to peanut protein prevents oral tolerance and enhances allergic sensitization. Clin Exp Allergy 2005; 35:757-66.
30. Strid J, Strobel S. Skin barrier dysfunction and systemic sensitization to allergens through the skin. Curr Drug Targets Inflamm Allergy 2005; 4:531-41.
31. Kawabe Y, Ochi A. Selective anergy of V beta 8 + , CD4 + T cells in Staphylococcus enterotoxin B-primed mice. J Exp Med 1990; 172:1065-70.
32. Rellahan BL, Jones LA, Kruisbeek AM, Fry AM, Matis LA. In vivo induction of anergy in peripheral V beta 8 + T cells by staphylococcal enterotoxin B. J Exp Med 1990; 172:1091-100.
33. Sundstedt A, Hoiden I, Hansson J, Hedlund G, Kalland T, Dohlsten M. Superantigen-induced anergy in cytotoxic CD8 + T cells. J Immunol 1995; 154:6306-13.
34. Savinko T, Lauerma A, Lehtimaki S et al. Topical superantigen exposure induces epidermal accumulation of CD8 + T cells, a mixed Th1/Th2-type dermatitis and vigorous production of IgE antibodies in the murine model of atopic dermatitis. J Immunol 2005; 175:8320-6.
35. Abernathy-Carver KJ, Sampson HA, Picker LJ, Leung DY. Milk-induced eczema is associated with the expansion of T cells expressing cutaneous lymphocyte antigen. J Clin Invest 1995; 95:913-8.
36. Novak N, Bieber T, Leung DY. Immune mechanisms leading to atopic dermatitis. J Allergy Clin Immunol 2003; 112(6 Suppl.):S128-39.
37. Schleimer RP, Togias AG. Introduction: systemic aspects of allergic disease. J Allergy Clin Immunol 2000; 106:S191.
38. Sicherer SH, Sampson HA. Food hypersensitivity and atopic dermatitis: pathophysiology, epidemiology, diagnosis, and management. J Allergy Clin Immunol 1999; 2:S114-22.
39. van Reijsen FC, Bruijnzeel-Koomen CA, Kalthoff FS et al. Skin-derived aeroallergen-specific T-cell clones of Th2 phenotype in patients with atopic dermatitis. J Allergy Clin Immunol 1992; 90:184-93.
40. Wollenberg A, Kraft S, Oppel T, Bieber T. Atopic dermatitis: pathogenetic mechanisms. Clin Exp Dermatol 2000; 25:530-4.
41. Mackay CR, Marston WL, Dudler L. Naive and memory T cells show distinct pathways of lymphocyte recirculation. J Exp Med 1990; 171:801-17.
42. Boguniewicz M, Leung DY. Recent insights into atopic dermatitis and implications for management of infectious complications. J Allergy Clin Immunol 2010; 125:4-13; quiz 4-5.
43. Buonpane RA, Churchill HR, Moza B et al. Neutralization of staphylococcal enterotoxin B by soluble, high-affinity receptor antagonists. Nat Med 2007; 13:725-9.
44. Yang X, Buonpane RA, Moza B et al. Neutralization of multiple staphylococcal superantigens by a single-chain protein consisting of affinity-matured, variable domain repeats. J Infect Dis 2008; 198:344-8.
45. Liu T, Wang BQ, Zheng PY, He SH, Yang PC. Rhinosinusitis derived Staphylococcal enterotoxin B plays a possible role in pathogenesis of food allergy. BMC Gastroenterol 2006; 6:24.
46. Ardern-Jones MR, Black AP, Bateman EA, Ogg GS. Bacterial superantigen facilitates epithelial presentation of allergen to T helper 2 cells. Proc Natl Acad Sci USA 2007; 104:5557-62.
47. Yawalkar N, Uguccioni M, Scharer J et al. Enhanced expression of eotaxin and CCR3 in atopic dermatitis. J Invest Dermatol 1999; 113:43-8.