Sympathetic nerve stimulation induces local endothelial Ca 2+ signals to oppose vasoconstriction of mouse mesenteric arteries

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 302, Issue 3, 2012, Pages

  Nausch, Lydia W M ^a   Bonev, Adrian D ^a   Heppner, Thomas J ^a   Tallini, Yvonne ^b   Kotlikoff, Michael I ^b   Nelson, Mark T ^a,c  

^a UNIVERSITY OF VERMONT   (United States)

^b Animal Health Diagnostic Center   (United States)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Calcium signaling; Endothelial cells; Endothelium; Inositol 1,4,5 trisphos phate receptors; Myoendothelial junction; Vascular smooth muscle

Indexed keywords

ALPHA ADRENERGIC RECEPTOR; CALCIUM CHANNEL; CALCIUM ION; INOSITOL 1,4,5 TRISPHOSPHATE; NORADRENALIN; PHENYLEPHRINE; PRAZOSIN; PURINERGIC RECEPTOR; RYANODINE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM SIGNALING; CONTROLLED STUDY; ENDOTHELIUM CELL; MESENTERIC ARTERY; MOUSE; NEGATIVE FEEDBACK; NERVE STIMULATION; NONHUMAN; PRIORITY JOURNAL; SYMPATHETIC NERVE; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

ANIMALS; CALCIUM; CALCIUM SIGNALING; CONNEXINS; ENDOTHELIUM, VASCULAR; FEEDBACK, PHYSIOLOGICAL; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; MESENTERIC ARTERIES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUSCLE, SMOOTH, VASCULAR; RECEPTORS, ADRENERGIC, ALPHA; SYMPATHETIC NERVOUS SYSTEM; VASOCONSTRICTION;

EID: 84856441778     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00773.2011     Document Type: Article

References (46)

1. Allbritton NL, Meyer T, Stryer L. Range of messenger action of calcium ion and inositol 1,4,5-trisphosphate. Science 258: 1812-1815, 1992.
2. + channel in porcine coronary artery endothelium: relevance to EDHF. Br J Pharmacol 135: 1133-1143, 2002.
3. + channel in porcine coronary endothelium: relevance to EDHF. Br J Pharmacol 137: 1346-1354, 2002.
4. Dora KA, Doyle MP, Duling BR. Elevation of intracellular calcium in smooth muscle causes endothelial cell generation of NO in arterioles. Proc Natl Acad Sci USA 94: 6529-6534, 1997.
5. Feletou M, Huang Y, Vanhoutte PM. Endothelium-mediated control of vascular tone: COX-1 and COX-2 products. Br J Pharmacol 164: 894-912, 2011.
6. Feletou M, Vanhoutte PM. EDHF: an update. Clin Sci (Lond) 117: 139-155, 2009.
7. Haddock RE, Grayson TH, Brackenbury TD, Meaney KR, Neylon CB, Sandow SL, Hill CE. Endothelial coordination of cerebral vasomo-tion via myoendothelial gap junctions containing connexins 37 and 40. Am J Physiol Heart Circ Physiol 291: H2047-H2056, 2006.
8. Hannah RM, Dunn KM, Bonev AD, Nelson MT. Endothelial SKCa and IKCa channels regulate brain parenchymal arteriolar diameter and cortical cerebral blood flow. J Cereb Blood Flow Metab 31: 1175-1186, 2011.
9. Heppner TJ, Layne JJ, Pearson JM, Sarkissian H, Nelson MT. Unique properties of muscularis mucosae smooth muscle in guinea pig urinary bladder. Am J Physiol Regul Integr Comp Physiol 301: R351-R362, 2011.
10. Hill-Eubanks DC, Werner ME, Heppner TJ, Nelson MT. Calcium Signaling in Smooth Muscle. Cold Spring Harb Perspect Biol 3: a004549, 2011.
11. 2+ signaling networks. J Gen Physiol 136: 149-154, 2010.
12. Iino M, Tsukioka M. Feedback control of inositol trisphosphate signalling bycalcium. Mol Cell Endocrinol 98: 141-146, 1994.
13. Imlach WL, Finch SC, Miller JH, Meredith AL, Dalziel JE. A role for BK channels in heart rate regulation in rodents. PLos One 5: e8698, 2010.
14. 2+ in hamster cremaster arterioles. Br J Pharmacol 155: 514-524, 2008.
15. 2+ waves by UTP in rat cerebral artery smooth muscle cells. Am J Physiol Cell Physiol 279: C1528-C1539, 2000.
16. 2+ events in endothelial cells reflect signalling through myoendothelial gap junctions in pressurized mesenteric arteries. Cell Calcium 44: 135-146, 2008.
17. Kapela A, Bezerianos A, Tsoukias NM. A mathematical model of vasoreactivity in rat mesenteric arterioles: I. Myoendothelial communication. Microcirculation 16: 694-713, 2009.
18. 2+ wave activity and alters contractile responses of murine gastric antrum. Am J Physiol Cell Physiol 294: C432-C441, 2008.
19. 2+ and ecNOS activity. Am J Physiol Heart Circ Physiol 276: H961-H969, 1999.
20. + channels in human mesenteric artery: a single-cell reverse transcriptase-polymerase chain reaction and electrophysiological study in situ. Circ Res 87: 496-503, 2000.
21. Kong JQ, Taylor DA, Fleming WW. Functional distribution and role of alpha-1 adrenoceptor subtypes in the mesenteric vasculature of the rat. J Pharmacol Exp Ther 268: 1153-1159, 1994.
22. Lamboley M, Pittet P, Koenigsberger M, Sauser R, Beny JL, Meister JJ. Evidence for signaling via gap junctions from smooth muscle to endothelial cells in rat mesenteric arteries: possible implication of a second messenger. Cell Calcium 37: 311-320, 2005.
23. 2+ transients during neurogenic contractions of rat mesenteric small arteries. J Physiol 549: 801-808, 2003.
24. 2+ transients in mesenteric small arteries. Am J Physiol Heart Circ Physiol 291: H3106-H3113, 2006.
25. 2+ transients (jCaTs) in rat small arteries. Circ Res 91: 454-456, 2002.
26. + channels in murine endothelial cells: block by intracellular calcium and magnesium. J Gen Physiol 131: 125-135, 2008.
27. Ledoux J, Taylor MS, Bonev AD, Hannah RM, Solodushko V, Shui B, Tallini Y, Kotlikoff MI, Nelson MT. Functional architecture of inositol 1,4,5-trisphosphate signaling in restricted spaces of myoendothelial projections. Proc Natl Acad Sci USA 105: 9627-9632, 2008.
28. Ledoux J, Werner ME, Brayden JE, Nelson MT. Calcium-activated potassium channels and the regulation of vascular tone. Physiology (Bethesda) 21: 69-78, 2006.
29. + channels in rat mesenteric arterial cells. Eur J Pharmacol 372: 103-107, 1999.
30. Mather S, Dora KA, Sandow SL, Winter P, Garland CJ. Rapid endothelial cell-selective loading of connexin 40 antibody blocks endothelium-derived hyperpolarizing factor dilation in rat small mesenteric arteries. Circ Res 97: 399-407, 2005.
31. 2+ oscillations. Am J Physiol Heart Circ Physiol 280: H2399-H2405, 2001.
32. Moncada S, Higgs EA. The discovery of nitric oxide and its role in vascular biology. Br J Pharmacol 147, Suppl 1: S193-S201, 2006.
33. Rummery NM, Brock JA, Pakdeechote P, Ralevic V, Dunn WR. ATP is the predominant sympathetic neurotransmitter in rat mesenteric arteries at high pressure. J Physiol 582: 745-754, 2007.
34. Sandow SL, Grayson TH. Limits of isolation and culture: intact vascular endothelium and BKCa. Am J Physiol Heart Circ Physiol 297: H1-H7, 2009.
35. Sandow SL, Haddock RE, Hill CE, Chadha PS, Kerr PM, Welsh DG, Plane F. What's where and why at a vascular myoendothelial microdo-main signalling complex. Clin Exp Pharmacol Physiol 36: 67-76, 2009.
36. Sandow SL, Neylon CB, Chen MX, Garland CJ. Spatial separation of endothelial small- and intermediate-conductance calcium-activated potassium channels (KCa) and connexins: possible relationship to vasodilator function? J Anat 209: 689-698, 2006.
37. Schuster A, Oishi H, Beny JL, Stergiopulos N, Meister JJ. Simultaneous arterial calcium dynamics and diameter measurements: application to myoendothelial communication. Am J Physiol Heart Circ Physiol 280: H1088-H1096, 2001.
38. Straub AC, Billaud M, Johnstone SR, Best AK, Yemen S, Dwyer ST, Looft-Wilson R, Lysiak JJ, Gaston B, Palmer L, Isakson BE. Compartmentalized connexin 43 S-nitrosylation/denitrosylation regulates het-erocellular communication in the vessel wall. Arterioscler Thromb Vasc Biol 31: 399-407, 2011.
39. 2+ waves and arteriolar dilation in vivo: measurements in Cx40BAC GCaMP2 transgenic mice. Circ Res 101: 1300-1309, 2007.
40. + (SK3) channels modulates arterial tone and blood pressure. Circ Res 93: 124-131, 2003.
41. Todorov LD, Mihaylova-Todorova ST, Bjur RA, Westfall DP. Differential cotransmission in sympathetic nerves: role of frequency of stimulation and prejunctional autoreceptors. J Pharmacol Exp Ther 290: 241-246, 1999.
42. Tuttle JL, Falcone JC. Nitric oxide release during a1-adrenoceptor-mediated constriction of arterioles. Am J Physiol Heart Circ Physiol 281: H873-H881, 2001.
43. Williams TJ, Clarke DE. Characterization of alpha 1-adrenoceptors mediating vasoconstriction to noradrenaline and nerve stimulation in the isolated perfused mesentery of rat. Br J Pharmacol 114: 531-536, 1995.
44. Winter P, Dora KA. Spreading dilatation to luminal perfusion of ATP and UTP in rat isolated small mesenteric arteries. J Physiol 582: 335-347, 2007.
45. Wray S, Burdyga T, Noble K. Calcium signalling in smooth muscle. Cell Calcium 38: 397-407, 2005.
46. 2+ signaling in arterial smooth muscle. Acta Pharmacol Sin 27: 1515-1525, 2006.