Impulse control disorders in Parkinson's disease: Clinical characteristics and implications

Neuropsychiatry

Volumn 1, Issue 2, 2011, Pages 133-147

  Leeman, Robert F ^a   Potenza, Marc N ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMANTADINE; DOPAMINE; DOPAMINE RECEPTOR STIMULATING AGENT; LEVODOPA;

ALCOHOLISM; BINGE EATING DISORDER; BRAIN CORTEX; BRAIN DEPTH STIMULATION; CLINICAL FEATURE; CLINICAL STUDY; COGNITIVE DEFECT; CORPUS STRIATUM; DEMOGRAPHY; DEPRESSION; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DRUG DOSE REDUCTION; FAMILY HISTORY; FUNCTIONAL DISEASE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; HYPERSEXUALITY; HYPOMANIA; IMPULSE CONTROL DISORDER; IMPULSIVENESS; MARRIAGE; MOTIVATION; NEUROBIOLOGY; OBSESSIVE COMPULSIVE DISORDER; ONSET AGE; PARKINSON DISEASE; PATHOLOGICAL GAMBLING; POSITRON EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; PRIORITY JOURNAL; REVIEW; RISK ASSESSMENT; RISK FACTOR; SEX DIFFERENCE; SHOPPING; SMOKING; WEIGHT GAIN;

EID: 84856439158     PISSN: 17582008     EISSN: 17582016     Source Type: Journal    
DOI: 10.2217/npy.11.11     Document Type: Review

References (80)

1. Kenangil G, Özekmekçi S, Sohtaoglu M et al.: Compulsive behaviors in patients with Parkinson's disease. Neurologist 16(3), 192-195 (2010).
2. Weintraub D, Koester J, Potenza MN et al.: Impulse control disorders in Parkinson disease: a cross-sectional study of 3090 patients. Arch. Neurol. 67(5), 589-595 (2010).
3. Potenza MN, Voon V, Weintraub D: Drug insight: impulse control disorders and dopamine therapies in Parkinson's disease. Nat. Clin. Pract. Neurol. 3(12), 664-672 (2007). (Pubitemid 350238058)
4. Voon V, Potenza MN, Thomsen T: Medication-related impulse control and repetitive behaviors in Parkinson's disease. Curr. Opin. Neurol. 20(4), 484-492 (2007). (Pubitemid 47051998)
5. Bernheimer H, Birkmayer W, Hornykiewicz O et al.: Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations. J. Neurol. Sci. 20(4), 415-455 (1973).
6. Fearnley J, Lees AJ: Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain 114(Pt 5), 2283-2301 (1991).
7. Housden CR, O'Sullivan SS, Joyce EM et al.: Intact reward learning but elevated delay discounting in Parkinson's disease patients with impulsive-compulsive spectrum behaviors. Neuropsychopharmacology 35(11), 2155-2164 (2010).
8. Bodi N, Keri S, Nagy H et al.: Reward-learning and the novelty-seeking personality: a between-and within-subjects study of the effects of dopamine agonists on young Parkinsons patients. Brain 132(9), 2385-2395 (2009).
9. Linazasoro G: Dopamine dysregulation syndrome and levodopa-induced dyskinesias in Parkinson disease: common consequences of anomalous forms of neural plasticity. Clin. Neuropharmacol. 32(1), 22-27 (2009).
10. Evans AH, Strafella AP, Weintraub D et al.: Impulsive and compulsive behaviors in Parkinson's disease. Mov. Disord. 24(11), 1561-1570 (2009).
11. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 4th Edition. American Psychiatric Association, Washington, DC, USA (1994).
12. Weintraub D, Hoops S, Shea JA et al.: Validation of the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease. Mov. Disord. 24(10), 1461-1467 (2009).
13. Gallagher DA, O'Sullivan SS, Evans AH et al.: Pathological gambling in Parkinson's disease: risk factors and differences from dopamine dysregulation. An analysis of published case series. Mov. Disord. 22(12), 1757-1763 (2007). (Pubitemid 47597599)
14. Thobois S, Ardouin C, Lhommee E et al.: Non-motor dopamine withdrawal syndrome after surgery for Parkinson's disease: predictors and underlying mesolimbic denervation. Brain 133(Pt 4), 1111-1127 (2010).
15. Holden C: 'Behavioral' addictions: do they exist? Science 294(5544), 980-982 (2001).
16. Potenza MN: The neurobiology of pathological gambling and drug addiction: an overview and new findings. Philos. Trans. R Soc. Lond. B Biol. Sci. 363(1507), 3181-3189 (2008).
17. Holden C: Behavioral addictions debut in proposed DSM-V. Science 327(5968), 935 (2010).
18. Koran L, Faber R, Aboujaoude E et al.: Estimated prevalence of compulsive buying in the United States. Am. J. Psychiatry 163(10), 1806-1812 (2006). (Pubitemid 44522491)
19. Alegria A, Petry N, Hasin D et al.: Disordered gambling among racial and ethnic groups in the US: results from the National Epidemiologic Survey on Alcohol and Related Conditions. CNS Spectr. 14(3), 132-142 (2009).
20. Ladd GT, Petry NM: Disordered gambling among university-based medical and dental patients: a focus on internet gambling. Psychol. Addict. Behav. 16(1), 76-79 (2002). (Pubitemid 34242487)
21. Frank MJ, Seeberger LC, O'Reilly RC: By carrot or by stick: cognitive reinforcement learning in Parkinsonism. Science 306(5703), 1940-1943 (2004). (Pubitemid 39627859)
22. Volkow ND, Fowler JS, Wang GJ: The addicted human brain: insights from imaging studies. J. Clin. Invest. 111(10), 1444-1451 (2003). (Pubitemid 38063274)
23. Price A, Filoteo JV, Maddox WT: Rule-based category learning in patients with Parkinson's disease. Neuropsychologia 47(5), 1213-1226 (2009).
24. Rowe JB, Hughes L, Ghosh BCP et al.: Parkinson's disease and dopaminergic therapy-differential effects on movement, reward and cognition. Brain 131(8), 2094-2105 (2008).
25. Bickel W, Marsch L: Toward a behavioral economic understanding of drug dependence: delay discounting processes. Addiction 96(1), 73-86 (2001). (Pubitemid 32099341)
26. Dick DM, Smith G, Olausson P et al.: Understanding the construct of impulsivity and its relationship to alcohol use disorders. Addict. Biol. 15(2), 217-226 (2010).
27. Voon V, Reynolds B, Brezing C et al.: Impulsive choice and response in dopamine agonist-related impulse control behaviors. Psychopharmacology 207(4), 645-659 (2010).
28. Ballanger B, van Eimeren T, Moro E et al.: Stimulation of the subthalamic nucleus and impulsivity: release your horses. Ann. Neurol. 66(6), 817-824 (2009).
29. Lim SY, O'Sullivan SS, Kotschet K et al.: Dopamine dysregulation syndrome, impulse control disorders and punding after deep brain stimulation surgery for Parkinson's disease. J. Clin. Neurosci. 16(9), 1148-1152 (2009).
30. Cools R, Barker RA, Sahakian B et al.: Enhanced or impaired cognitive function in Parkinson's disease as a function of dopaminergic medication and task demands. Cereb. Cortex 11(12), 1136-1143 (2001). (Pubitemid 33108240)
31. Cools R, Barker RA, Sahakian B et al.: l-Dopa medication remediates cognitive inflexibility, but increases impulsivity in patients with Parkinson's disease. Neuropsychologia 41(11), 1431-1141 (2003).
32. Ardouin C, Voon V, Worbe Y et al.: Pathological gambling in Parkinson's disease improves on chronic subthalamic nucleus stimulation. Mov. Disord. 21(11), 1941-1946 (2006). (Pubitemid 44848942)
33. Driver-Dunckley E, Samanta J, Stacy M: Pathological gambling associated with dopamine agonist therapy in Parkinson's disease. Neurology 61(3), 422-423 (2003). (Pubitemid 36975988)
34. Voon V, Hassan K, Zurowski M et al.: Prospective prevalence of pathologic gambling and medication association in Parkinson disease. Neurology 66(11), 1750-1752 (2006). (Pubitemid 43964638)
35. Weintraub D, Siderowf AD, Potenza MN et al.: Association of dopamine agonist use with impulse control disorders in Parkinson disease. Arch. Neurol. 63(7), 969-973 (2006). (Pubitemid 44036299)
36. Cilia R, Ko JH, Cho SS et al.: Reduced dopamine transporter density in the ventral striatum of patients with Parkinson's disease and pathological gambling. Neurobiol. Dis. 39(1), 98-104 (2010).
37. Evans AH, Lawrence AD, Potts J et al.: Relationship between impulsive sensation seeking traits, smoking, alcohol and caffeine intake, and Parkinson's disease. J. Neurol. Neurosurg. Psychiatry 77(3), 317-321 (2006).
38. Voon V, Thomsen T, Miyasaki JM et al.: Factors associated with dopaminergic drug-related pathological gambling in Parkinson disease. Arch. Neurol. 64(2), 212-216 (2007).
39. Kobayakawa M, Tsuruya N, Kawamura M: Sensitivity to reward and punishment in Parkinson's disease: an analysis of behavioral patterns using a modified version of the Iowa gambling task. Parkinsonism Relat. Disord. 16(7), 453-457 (2010).
40. Bechara A, Damasio A, Damasio H et al.: Insensitivity to future consequences following damage to human prefrontal cortex. Cognition 50(1-3), 7-15 (1994).
41. Pagonabarraga J, García-Sánchez C, Llebaria G et al.: Controlled study of decision-making and cognitive impairment in Parkinson's disease. Mov. Disord. 22(10), 1430-1435 (2007). (Pubitemid 47280628)
42. van Eimeren T, Ballanger B, Pellecchia G et al.: Dopamine agonists diminish value sensitivity of the orbitofrontal cortex: a trigger for pathological gambling in Parkinson's disease. Neuropsychopharmacology 34(13), 2758-2766 (2009).
43. Lejuez C, Read J, Kahler C et al.: Evaluation of a behavioral measure of risk taking: the Balloon Analogue Risk Task (BART). J. Exp. Psychol. Appl. 8(2), 75-84 (2002).
44. Hamidovic A, Kang UJ, De Wit H: Effects of low to moderate acute doses of pramipexole on impulsivity and cognition in healthy volunteers. J. Clin. Psychopharmacol. 28(1), 45-51 (2008).
45. Kirby KN, Petry NM, Bickel WK: Heroin addicts have higher discount rates for delayed rewards than non-drug-using controls. J. Exp. Psychol. Gen. 128(1), 78-87 (1999).
46. Reynolds B, Schiffbauer R: Measuring state changes in human delay discounting: an experiential discounting task. Behav. Processes 67(3), 343-356 (2004). (Pubitemid 39420142)
47. Rao H, Mamikonyan E, Detre JA et al.: Decreased ventral striatal activity with impulse control disorders in Parkinson's disease. Mov. Disord. 25(11), 1660-1669 (2010).
48. Djamshidian A, O'Sullivan SS, Doherty K et al.: Altruistic punishment in patients with Parkinson's disease with and without impulsive behaviour. Neuropsychologia 49(1), 103-107 (2011).
49. Cools R, Lewis S, Clark L et al.: l-Dopa disrupts activity in the nucleus accumbens during reversal learning in Parkinson's disease. Neuropsychopharmacology 32(1), 180-189 (2007). (Pubitemid 44967796)
50. Steeves TDL, Miyasaki J, Zurowski M et al.: Increased striatal dopamine release in Parkinsonian patients with pathological gambling: a [11C] raclopride PET study. Brain 132(5), 1376-1385 (2009).
51. Everitt B, Robbins T: Neural systems of reinforcement for drug addiction: from addiction to habits to compulsion. Nat. Neurosci. 8(11), 1481-1489 (2005). (Pubitemid 41573659)
52. Volkow N, Wang G, Telang F et al.: Cocaine cues and dopamine in dorsal striatum: mechanism of craving in cocaine addiction. J. Neurosci. 26(24), 6583-6588 (2006). (Pubitemid 44318339)
53. Volkow N, Fowler J, Wang G et al.: Dopamine in drug abuse and addiction: results of imaging studies and treatment implications. Arch. Neurol. 64(11), 1575-1579 (2007). (Pubitemid 350106758)
54. Reuter J, Raedler T, Rose M et al.: Pathological gambling is linked to reduced activation of the mesolimbic reward system. Nat. Neurosci. 8(2), 147-148 (2005). (Pubitemid 40194043)
55. van Eimeren T, Pellecchia G, Cilia R et al.: Drug-induced deactivation of inhibitory networks predicts pathological gambling in PD. Neurology 75(19), 1711-1716 (2010).
56. Evans AH, Pavese N, Lawrence AD et al.: Compulsive drug use linked to sensitized ventral striatal dopamine transmission. Ann. Neurol. 59(5), 852-858 (2006). (Pubitemid 43673163)
57. Antonini A, Tolosa E, Mizuno Y et al.: A reassessment of risks and benefits of dopamine agonists in Parkinson's disease. Lancet Neurol. 8(10), 929-937 (2009).
58. Molina JA, Sainz-Artiga MJ, Fraile A et al.: Pathologic gambling in Parkinson's disease: a behavioral manifestation of pharmacologic treatment? Mov. Disord. 15(5), 869-872 (2000).
59. Sohtaoglu M, Demiray DY, Kenangil G et al.: Long term follow-up of Parkinson's disease patients with impulse control disorders. Parkinsonism Rel. Disord. 16(5), 334-337 (2010).
60. Voon V, Sohr M, Lang AE et al.: Impulse control disorders in Parkinson disease: a multicenter case-control study. Ann. Neurol. (2011) (In Press).
61. Mamikonyan E, Siderowf AD, Duda JE et al.: Long-term follow-up of impulse control disorders in Parkinson's disease. Mov. Disord. 23(1), 75-80 (2008). (Pubitemid 351281221)
62. Thomas A, Bonanni L, Gambi F et al.: Pathological gambling in Parkinson disease is reduced by amantadine. Ann. Neurol. 68(3), 400-404 (2010).
63. Weintraub D, Sohr M, Potenza MN et al.: Amantadine use associated with impulse control disorders in Parkinson disease in cross-sectional study. Ann. Neurol. 68(6), 963-968 (2010).
64. Kleiner-Fisman G, Herzog J, Fisman DN et al.: Subthalamic nucleus deep brain stimulation: summary and meta-analysis of outcomes. Mov. Disord. 21(Suppl. 14), S290-S304 (2006). (Pubitemid 44028288)
65. Rodriguez-Oroz MC, López-Azcárate J, Garcia-Garcia D et al.: Involvement of the subthalamic nucleus in impulse control disorders associated with Parkinsons disease. Brain. 134(Pt 1), 36-49 (2010).
66. Grant JE, Kim SW, Hartman BK: A double-blind, placebo-controlled study of the opiate antagonist naltrexone in the treatment of pathological gambling urges. J. Clin. Psychiatry 69(5), 783-789 (2008). (Pubitemid 351838687)
67. Petry NM: Patterns and correlates of Gamblers Anonymous attendance in pathological gamblers seeking professional treatment. Addict. Behav. 28(6), 1049-1062 (2003). (Pubitemid 36808515)
68. McCloskey MS, Noblett KL, Deffenbacher JL et al.: Cognitive-behavioral therapy for intermittent explosive disorder: a pilot randomized clinical trial. J. Consult. Clin. Psychol. 76(5), 876-886 (2008).
69. Petry NM, Ammerman Y, Bohl J et al.: Cognitive-behavioral therapy for pathological gamblers. J. Consult. Clin. Psychol. 74(3), 555-567 (2006). (Pubitemid 44128235)
70. Winstanley CA, Cocker PJ, Rogers RD: Dopamine modulates reward expectancy during performance of a slot machine task in rats: evidence for a 'near-miss' effect. Neuropsychopharmacology (2011) (Epub ahead of print).
71. Zeeb FD, Robbins TW, Winstanley CA: Serotonergic and dopaminergic modulation of gambling behavior as assessed using a novel rat gambling task. Neuropsychopharmacology 34(10), 2329-2343 (2009).
72. Frank MJ, Samanta J, Moustafa AA et al.: Hold your horses: impulsivity, deep brain stimulation, and medication in Parkinsonism. Science 318(5854), 1309-1312 (2007). (Pubitemid 350172897)
73. Bostwick JM, Hecksel KA, Stevens SR et al.: Frequency of new-onset pathologic compulsive gambling or hypersexuality after drug treatment of idiopathic Parkinson disease. Mayo Clin. Proc. 84(4), 310-316 (2009).
74. Giladi N, Weitzman N, Schreiber S et al.: New onset heightened interest or drive for gambling, shopping, eating or sexual activity in patients with Parkinson's disease: the role of dopamine agonist treatment and age at motor symptoms onset. J. Psychopharmacol. 21(5), 501-506 (2007). (Pubitemid 47106924)
75. Pontone G, Williams JR, Bassett SS et al.: Clinical features associated with impulse control disorders in Parkinson disease. Neurology 67(7), 1258-1261 (2006). (Pubitemid 44563839)
76. Nirenberg M, Waters C: Compulsive eating and weight gain related to dopamine agonist use. Mov. Disord. 21(4), 524-529 (2006).
77. Lawrence AD, Evans AH, Lees AJ: Compulsive use of dopamine replacement therapy in Parkinson's disease: reward systems gone awry? Lancet Neurol. 2(10), 595-604 (2003). (Pubitemid 37162568)
78. Avanzi M, Barratti M, Cabrini S et al.: Prevalence of pathological gambling in patients with Parkinson's disease. Mov. Disord. 21(12), 2068-2072 (2006). (Pubitemid 46140413)
79. Grosset K, MacPhee G, Pal G et al.: Problematic gambling on dopamine agonists: not such a rarity. Mov. Disord. 21(12), 2206-2208 (2006). (Pubitemid 46140438)
80. Lu C, Bharmal A, Suchowersky O: Gambling and Parkinson disease. Arch. Neurol. 63(2), 298 (2006).