Gliclazide does not fully prevent 2-deoxy-D-ribose-induced oxidative damage because it does not restore glutathione content in a pancreatic β-cell line

Oxidative Medicine and Cellular Longevity

Volumn , Issue , 2012, Pages

  Koh, Gwanpyo ^a   Kim, Min Kyoung ^a   Yang, Eun Jin ^a   Lee, Dae Ho ^a  

^a Jeju National University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ANNEXINS; ANTIDIABETIC AGENTS; ANTIOXIDANT PROPERTIES; BLUE STAINING; CELL LINES; CELL-FREE SYSTEM; FENTON REACTIONS; FREE RADICAL SCAVENGING; GLICLAZIDE; GLUTATHIONE CONTENTS; GLUTATHIONES; HIT-T15 CELLS; HYDROXYL RADICALS; N-ACETYL-L-CYSTEINE; OXIDATIVE DAMAGE; REACTIVE OXYGEN SPECIES; SIMILAR DEGREE;

AMINO ACIDS; CELL CULTURE; CELL DEATH; FLOW CYTOMETRY; FREE RADICALS; MAGNETIC MOMENTS; RESTORATION;

PEPTIDES;

2 DEOXYRIBOSE; ACETYLCYSTEINE; DIHYDRORHODAMINE 123; GLICLAZIDE; GLUTATHIONE; HYDROXYL RADICAL; LIPOCORTIN 5; REACTIVE OXYGEN METABOLITE; SCAVENGER; TRYPAN BLUE; ANTIDIABETIC AGENT; DEOXYRIBOSE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL DEATH; CELL FREE SYSTEM; CONTROLLED STUDY; ELECTRON SPIN RESONANCE; FENTON REACTION; FLOW CYTOMETRY; FLUORESCENCE ANALYSIS; IN VIVO STUDY; NONHUMAN; PANCREAS ISLET BETA CELL; PROTEIN DEPLETION; STAINING; ANIMAL; CELL LINE; CELL SURVIVAL; DRUG ANTAGONISM; DRUG EFFECT; DRUG INTERACTION; HAMSTER; METABOLISM; OXIDATIVE STRESS;

ACETYLCYSTEINE; ANIMALS; APOPTOSIS; CELL LINE; CELL SURVIVAL; CRICETINAE; DEOXYRIBOSE; DRUG INTERACTIONS; GLICLAZIDE; GLUTATHIONE; HYDROXYL RADICAL; HYPOGLYCEMIC AGENTS; INSULIN-SECRETING CELLS; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES;

EID: 84856425666     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2012/390678     Document Type: Article

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