Age is an important predictor of kidney transplantation outcome

Nephrology Dialysis Transplantation

Volumn 27, Issue 4, 2012, Pages 1663-1671

  Veroux, Massimiliano ^a   Grosso, Giuseppe ^a   Corona, Daniela ^a   Mistretta, Antonio ^a   Giaquinta, Alessia ^a   Giuffrida, Giuseppe ^a   Sinagra, Nunzia ^a   Veroux, Pierfrancesco ^a  

^a UNIVERSITY OF CATANIA   (Italy)

Author keywords

age; elderly patients; expanded criteria donor; kidney transplantation, marginal donor

Indexed keywords

ADULT; AGE; AGED; ARTICLE; CONTROLLED STUDY; DONOR AGE; DONOR SELECTION; FEMALE; GERIATRIC PATIENT; GRAFT FAILURE; GRAFT RECIPIENT; GRAFT SURVIVAL; HOSPITAL ADMISSION; HUMAN; KIDNEY TRANSPLANTATION; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS; RECIPIENT AGE; RISK ASSESSMENT; SURGICAL RISK; SURVIVAL PREDICTION; SURVIVAL RATE; SURVIVAL TIME;

ADOLESCENT; ADULT; AGE FACTORS; AGED; FEMALE; FOLLOW-UP STUDIES; GRAFT REJECTION; GRAFT SURVIVAL; HUMANS; INCIDENCE; ITALY; KIDNEY FAILURE, CHRONIC; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; OUTCOME ASSESSMENT (HEALTH CARE); POSTOPERATIVE COMPLICATIONS; SURVIVAL RATE; TISSUE DONORS; WAITING LISTS; YOUNG ADULT;

EID: 84856424267     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfr524     Document Type: Article

References (51)

1. Schnuelle P, Lorenz D, Trede M et al. Impact of renal cadaveric transplantation on survival in end-stage renal failure: evidence for reduced mortality risk compared with hemodialysis during long-term follow-up. J Am Soc Nephrol 1998; 9: 2135-2141 (Pubitemid 28482164)
2. Port FK, Wolfe RA, Mauger EA et al. Comparison of survival probabilities for dialysis patients vs cadaveric renal transplant recipients. JAMA 1993; 270: 1339-1343 (Pubitemid 23267894)
3. Wolfe RA, Ashby VB, Milford EL et al. Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant. N Engl J Med 1999; 341: 1725-1730
4. Whiting JF, Zavala EY, Alexander JW et al. The cost-effectiveness of transplantation with expanded donor kidneys. Transplant Proc 1999; 31: 1320-1321 (Pubitemid 29127921)
5. Simmons RG, Anderson CR, Abress LK. Quality of life and rehabilitation differences among four end-stage renal disease therapy groups. Scand J Urol Nephrol Suppl 1990; 131: 7-22
6. Gokal R. Quality of life in patients undergoing renal replacement therapy. Kidney Int Suppl 1993; 40: S23-S27
7. Veroux M, Corona D, Patel VB et al. Quality of life in kidney transplantation. In: Handbook of Disease Burdens and Quality of Life Measures. New York, NY: Springer, 2009, pp. 2227-2238
8. Kontodimopoulos N, Niakas D. An estimate of lifelong costs and QALYs in renal replacement therapy based on patients' life expectancy. Health Policy 2008; 86: 85-96 (Pubitemid 351296306)
9. Laupacis A, Keown P, Pus N et al. A study of the quality of life and cost-utility of renal transplantation. Kidney Int 1996; 50: 235-242 (Pubitemid 26323718)
10. Wolfe RA, Roys EC, Merion RM. Trends in organ donation and transplantation in the United States, 1999-2008. Am J Transplant 2010; 10: 961-972
11. Lee CM, Scandling JD, Shen GK et al. The kidneys that nobody wanted: support for the utilization of expanded criteria donors. Transplantation 1996; 62: 1832-1841 (Pubitemid 27014548)
12. Moers C, Kornmann NS, Leuvenink HG et al. The influence of deceased donor age and old-for-old allocation on kidney transplant outcome. Transplantation 2009; 88: 542-552
13. Snanoudj R, Rabant M, Timsit MO et al. Donor-estimated GFR as an appropriate criterion for allocation of ECD kidneys into single or dual kidney transplantation. Am J Transplant 2009; 9: 2542-2551
14. Remuzzi G, Cravedi P, Perna A et al. Long-term outcome of renal transplantation from older donors. N Engl J Med 2006; 354: 343-352 (Pubitemid 43145059)
15. Rigotti P, Ekser B, Furian L et al. Outcome of renal transplantation from very old donors. N Engl J Med 2009; 360: 1464-1465
16. Ekser B, Furian L, Broggiato A et al. Technical aspects of unilateral dual kidney transplantation from expanded criteria donors: experience of 100 patients. Am J Transplant 2010; 10: 2000-2007
17. Terasaki PI, Gjertson DW, Cecka JM et al. Significance of the donor age effect on kidney transplants. Clin Transplant 1997; 11: 366-372 (Pubitemid 27460429)
18. Rao KV, Kasiske BL, Odlund MD et al. Influence of cadaver donor age on posttransplant renal function and graft outcome. Transplantation 1990; 49: 91-95 (Pubitemid 20051592)
19. Hariharan S, McBride MA, Bennett LE et al. Risk factors for renal allograft survival from older cadaver donors. Transplantation 1997; 64: 1748-1754 (Pubitemid 28041713)
20. Cho YW, Cecka JM, Gjertson DW et al. Prolonged hypertension (10 years) is a significant risk factor in older cadaver donor renal transplants. Transplant Proc 1999; 31: 1283 (Pubitemid 29127905)
21. Vivas CA, O'Donovan RM, Jordan ML et al. Cadaveric renal transplantation using kidneys from donors greater than 60 years old. Clin Transplant 2011; 6: 77-80
22. Meier-Kriesche HU, Ojo AO, Port FK et al. Survival improvement among patients with end-stage renal disease: trends over time for transplant recipients and wait-listed patients. J Am Soc Nephrol 2001; 12: 1293-1296 (Pubitemid 32472644)
23. Merion RM, Ashby VB, Wolfe RA et al. Deceased-donor characteristics and the survival benefit of kidney transplantation. JAMA 2005; 294: 2726-2733 (Pubitemid 41770102)
24. Tullius SG, Reutzel-Selke A, Egermann F et al. Contribution of prolonged ischemia and donor age to chronic renal allograft dysfunction. J Am Soc Nephrol 2000; 11: 1317-1324 (Pubitemid 30416229)
25. Tullius SG, Tran H, Guleria I et al. The combination of donor and recipient age is critical in determining host immunoresponsiveness and renal transplant outcome. Ann Surg 2010; 252: 662-674
26. Physical status: the use and interpretation of anthropometry. Report of a WHO Expert Committee. World Health Organ Tech Rep Ser 1995; 854: 1-452
27. Heldal K, Hartmann A, Leivestad T et al. Clinical outcomes in elderly kidney transplant recipients are related to acute rejection episodes rather than pretransplant comorbidity. Transplantation 2009; 87: 1045-1051
28. El-Agroudy AE, Al-Arrayed SM, Al-Arrayed AS et al. A single-center experience of renal transplantation in elderly patients. Ann Transplant 2009; 14: 26-32
29. Sener A, Schweitzer EJ, Munivenkatappa R et al. Deceased-donor renal transplantation in the geriatric population demonstrates equal graft survival compared with younger recipients. Transplantation 2009; 87: 1549-1554
30. Foss A, Heldal K, Scott H et al. Kidneys from deceased donors more than 75 years perform acceptably after transplantation. Transplantation 2009; 87: 1437-1441
31. Chavalitdhamrong D, Gill J, Takemoto S et al. Patient and graft outcomes from deceased kidney donors age 70 years and older: an analysis of the Organ Procurement Transplant Network/United Network of Organ Sharing database. Transplantation 2008; 85: 1573-1579
32. Giessing M, Fuller TF, Friedersdorff F et al. Outcomes of transplanting deceased-donor kidneys between elderly donors and recipients. J Am Soc Nephrol 2009; 20: 37-40
33. Ojo AO, Hanson JA, Meier-Kriesche H et al. Survival in recipients of marginal cadaveric donor kidneys compared with other recipients and wait-listed transplant candidates. J Am Soc Nephrol 2001; 12: 589-597 (Pubitemid 32180029)
34. Martin NJ, Ortega M, Gutierrez MJ et al. Survival of patients older than 60 years with kidneys transplanted from Spanish expanded criteria donors versus patients continued on hemodialysis. Transplant Proc 2009; 41: 2376-2378
35. Rao PS, Merion RM, Ashby VB et al. Renal transplantation in elderly patients older than 70 years of age: results from the Scientific Registry of Transplant Recipients. Transplantation 2007; 83: 1069-1074 (Pubitemid 46659119)
36. Schold JD, Kaplan B, Baliga RS et al. The broad spectrum of quality in deceased donor kidneys. Am J Transplant 2005; 5: 757-765 (Pubitemid 40461285)
37. Cuende N, Cuende JI, Fajardo J et al. Effect of population aging on the international organ donation rates and the effectiveness of the donation process. Am J Transplant 2007; 7: 1526-1535 (Pubitemid 46776244)
38. Meier-Kriesche HU, Cibrik DM, Ojo AO et al. Interaction between donor and recipient age in determining the risk of chronic renal allograft failure. J Am Geriatr Soc 2002; 50: 14-17 (Pubitemid 34053017)
39. Lankarani MM, Assari S, Nourbala MH. Improvement of renal transplantation outcome through matching donors and recipients. Ann Transplant 2009; 14: 20-25
40. Kwon OJ, Kwak JY, Kang CM. The impact of gender and age matching for long-term graft survival in living donor renal transplantation. Transplant Proc 2005; 37: 726-728 (Pubitemid 40590683)
41. Kwon OJ, Kwak JY. The impact of sex and age matching for longterm graft survival in living donor renal transplantation. Transplant Proc 2004; 36: 2040-2042 (Pubitemid 39424318)
42. Fritsche L, Horstrup J, Budde K et al. Old-for-old kidney allocation allows successful expansion of the donor and recipient pool. Am J Transplant 2003; 3: 1434-1439 (Pubitemid 37288090)
43. Johnson DW, Herzig K, Purdie D et al. A comparison of the effects of dialysis and renal transplantation on the survival of older uremic patients. Transplantation 2000; 69: 794-799 (Pubitemid 30174099)
44. USRDS. 2010 Annual Data Report, 2010,http://www.usrds.org/2010/pdf/v2-07. pdf (1 December 2010, date last accessed)
45. Centro. Nazionale Trapianti. Attività donazione e trapianto. 2010. http://www.trapianti.salute.gov.it/imgs/C-17-pubblicazioni-1511-allegato.pdf (1 December 2010, date last accessed)
46. Albrechtsen D, Leivestad T, Sodal G et al. Kidney transplantation in patients older than 70 years of age. Transplant Proc. 1995;27,986-988.
47. Schaubel D, Desmeules M, Mao Y et al. Survival experience among elderly end-stage renal disease patients. A controlled comparison of transplantation and dialysis. Transplantation 1995; 60: 1389-1394 (Pubitemid 26012668)
48. Oniscu GC, Brown H, Forsythe JL. How great is the survival advantage of transplantation over dialysis in elderly patients? Nephrol Dial Transplant 2004; 19: 945-951 (Pubitemid 38455669)
49. Bonal J, Cleries M, Vela E. Transplantation versus haemodialysis in elderly patients. Renal Registry Committee. Nephrol Dial Transplant 1997; 12: 261-264 (Pubitemid 27090976)
50. Kyllonen L, Ahonen J. Kidney transplantation in the elderly in Finland. Transplant Proc 1990; 22: 163-164 (Pubitemid 20112799)
51. Doyle SE, Matas AJ, Gillingham K et al. Predicting clinical outcome in the elderly renal transplant recipient. Kidney Int 2000; 57: 2144-2150 (Pubitemid 30252309)