A composite urine biomarker reflects interstitial inflammation in lupus nephritis kidney biopsies

Kidney International

Volumn 81, Issue 4, 2012, Pages 401-406

  Zhang, Xiaolan ^a   Nagaraja, Haikady N ^a   Nadasdy, Tibor ^a   Song, Huijuan ^a   McKinley, Alison ^a   Prosek, Jason ^a   Kamadana, Swapna ^a   Rovin, Brad H ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

cytokines; inflammation; interstitial fibrosis; systemic lupus erythematosus

Indexed keywords

CREATININE; FATTY ACID BINDING PROTEIN; HEPCIDIN; LIVER FATTY ACID BINDING PROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DIAGNOSTIC ERROR; DIAGNOSTIC TEST ACCURACY STUDY; DISCRIMINANT ANALYSIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; INTERSTITIAL NEPHRITIS; KIDNEY BIOPSY; KIDNEY FIBROSIS; LUPUS ERYTHEMATOSUS NEPHRITIS; MAJOR CLINICAL STUDY; MALE; NON INVASIVE PROCEDURE; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN URINE LEVEL; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; URINALYSIS;

EID: 84856414228     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2011.354     Document Type: Article

References (30)

1. Yu F, Wu LH, Tan Y et al. Tubulointerstitial lesions of patients with lupus nephritis classified by the 2003 International Society of Nephrology and Renal Pathology Society system. Kidney Int 2010; 77: 820-829.
2. Grootscholten C, Bajema IM, Florquin S et al. Treatment with cyclophosphamide delays the progression of chronic lesions more effectively than does treatment with azathioprine plus methylprednisolone in patients with proliferative lupus nephritis. Arthritis Rheum 2007; 56: 924-937. (Pubitemid 46399440)
3. Yoo CW, Kim M-K, Lee HS. Predictors of renal outcome in diffuse proliferative lupus nephropathy: data from repeat renal biopsy. Nephrol Dial Transplant 2000; 15: 1604-1608.
4. Gunnarsson I, Sundelin B, Heimburger M et al. Repeated renal biopsy in proliferative lupus nephritis-predictive role of serum C1q and albuminuria. J Rheumat 2002; 29: 693-699. (Pubitemid 34303862)
5. Hill GS, Delahousse M, Nochy D et al. Outcome of relapse in lupus nephritis: roles of reversal of renal fibrosis and response of inflammation to therapy. Kidney Int 2002; 61: 2176-2186. (Pubitemid 34539335)
6. Hill GS, Delahouse M, Nochy D et al. A new morphologic index for the evaluation of renal biopsies in lupus nephritis. Kidney Int 2000; 58: 1160-1173.
7. Varghese SA, Powell TB, Budisavljevic MN et al. Urine biomarkers predict the cause of glomerular disease. J Am Soc Nephrol 2007; 18: 913-922. (Pubitemid 46434508)
8. Oates JC, Varghese S, Bland AM et al. Prediction of urinary protein markers in lupus nephritis. Kidney Int 2005; 68: 2588-2592. (Pubitemid 43251004)
9. Weening JJ, D'Agati VD, Schwartz MM et al. The classification of glomerulonephritis in systemic lupus erythematosus revisited. J Am Soc Nephrol 2004; 15: 241-250. (Pubitemid 38140764)
10. Grootscholten C, Bajema IM, Florquin S et al. Interobserver agreement of scoring of histopathological characteristics and classification of lupus nephritis. Nephrol Dial Transplant 2008; 23: 223-230. (Pubitemid 351767369)
11. Schwartz MM, Korbet SM, Lewis EJ. The prognosis and pathogenesis of severe lupus glomerulonephritis. Nephrol Dial Transplant 2008; 23: 1298-1306. (Pubitemid 351767497)
12. Ayodele OE, Okpechi IG, Swanepoel CR. Predictors of poor renal outcome in patients with biopsy-proven lupus nephritis. Nephrology (Carlton, Vic) 15: 482-490.
13. Rovin BH, Song H, Birmingham DJ et al. Urine chemokines as biomarkers of human systemic lupus erythematosus activity. J Am Soc Nephrol 2005; 16: 467-473. (Pubitemid 41725143)
14. Rovin BH. The chemokine network in systemic lupus erythematosis nephritis. Front Biosci 2007; 13: 904-922.
15. Zhang X, Jin M, Wu H et al. Biomarkers of lupus nephritis determined by serial urine proteomics. Kidney Int 2008; 74: 799-807.
16. Zhang X, Rovin BH. Hepcidin expression by human monocytes in response to adhesion and pro-inflammatory cytokines. Biochim Biophys Acta 2010; 1800: 1262-1267.
17. Kamijo-Ikemori A, Sugaya T, Kimura K. Urinary fatty acid binding protein in renal disease. Clin Chim Acta 2006; 374: 1-7. (Pubitemid 44572240)
18. Corwin HL, Schwartz MM, Lewis EJ. The importance of sample size in the interpretation of the renal biopsy. Am J Nephrol 1988; 8: 85-89.
19. Racusen LC, Solez K, Colvin RB et al. The Banff 97 working classification of renal allograft pathology. Kidney Int 1999; 55: 713-723. (Pubitemid 29082898)
20. Seron D, Moreso F, Fulladosa X et al. Reliability of chronic allograft nephropathy diagnosis in sequential protocol biopsies. Kidney Int 2002; 61: 727-733. (Pubitemid 34102616)
21. Wu Q, Jinde K, Nishina M et al. Analysis of prognostic predictors in idiopathic membranous nephropathy. Am J Kidney Dis 2001; 37: 380-387. (Pubitemid 32116032)
22. Alexopoulos E, Stangou M, Papagianni A et al. Factors influencing the course and the response to treatment in primary focal segmental glomerulosclerosis. Nephrol Dial Transplant 2000; 15: 1348-1356.
23. Myllymaki JM, Honkanen TT, Syrjanen JT et al. Severity of tubulointerstitial inflammation and prognosis in immunoglobulin A nephropathy. Kidney Int 2007; 71: 343-348. (Pubitemid 46227094)
24. Roberts IS, Cook HT, Troyanov S et al. The Oxford classification of IgA nephropathy: pathology definitions, correlations, and reproducibility. Kidney Int 2009; 76: 546-556.
25. Cattran DC, Coppo R, Cook HT et al. The Oxford classification of IgA nephropathy: rationale, clinicopathological correlations, and classification. Kidney Int 2009; 76: 534-545.
26. Nguyen D, Ping F, Mu W et al. Macrophage accumulation in human progressive diabetic nephropathy. Nephrology (Carlton, Vic) 2006; 11: 226-231. (Pubitemid 43829442)
27. Heilman RL, Devarapalli Y, Chakkera HA et al. Impact of subclinical inflammation on the development of interstitial fibrosis and tubular atrophy in kidney transplant recipients. Am J Transplant 2010; 10: 563-570.
28. Rovin BH, Song H, Hebert LA et al. Plasma, urine, and renal expression of adiponectin in human systemic lupus erythematosus. Kidney Int 2005; 68: 1825-1833. (Pubitemid 43169928)
29. Hill GS, Delahousse M, Nochy D et al. Proteinuria and tubulointerstitial lesions in lupus nephritis. Kidney Int 2001; 60: 1893-1903. (Pubitemid 32999995)
30. Hsieh C, Chang A, Brandt D et al. Predicting outcomes of lupus nephritis with tubulointerstitial inflammation and scarring. Arthritis Care Res 2011; 63: 865-874.