Antihyperlipidemic activity of Salacia chinensis root extracts in triton-induced and atherogenic diet-induced hyperlipidemic rats

Indian Journal of Pharmacology

Volumn 44, Issue 1, 2012, Pages 88-92

  Sikarwar, Mukesh S ^a   Patil, M B ^a  

^a Karnatak Lingayat Education Society   (India)

Author keywords

Hyperlipidemia; Salacia chinensis; simvastatin; triton

Indexed keywords

ALCOHOL; ANTILIPEMIC AGENT; CHLOROFORM; CHOLESTEROL; ETHER; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; PETROLEUM; PLANT EXTRACT; SALACIA CHINENSIS EXTRACT; SIMVASTATIN; TRIACYLGLYCEROL; TYLOXAPOL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROGENIC DIET; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG SCREENING; HYPERLIPIDEMIA; LIPOPROTEIN BLOOD LEVEL; NONHUMAN; PLANT ROOT; RAT; SALACIA; SALACIA CHINENSIS; TRIACYLGLYCEROL BLOOD LEVEL;

EID: 84856386888     PISSN: 02537613     EISSN: 19983751     Source Type: Journal    
DOI: 10.4103/0253-7613.91875     Document Type: Article

References (18)

1. Ansarullah, Jadeja RN, Thounaojam MC, Patel V, Devkar RV, Ramachandran AV. Antihyperlipidemic potential of a polyherbal preparation on triton WR 1339 (Tyloxapol) induced hyperlipidemia: A comparison with lovastatin. Int J Green Pharm 2009;3:119-24.
2. Ghule BV, Ghante MH, Saoji AN, Yeole PG. Hypolipidemic and antihyperlipidemic effects of Lagenariasiceraria (Mol.) fruit extracts. Indian J Exp Biol 2006;44:905-9. (Pubitemid 44736231)
3. Nomura H, Kimura Y, Okamoto O, Shiraishi G. Effects of antihyperlipidemic drugs and diet plus exercise therapy in the treatment of patients with moderate Hypercholesterolemia. Clin Ther 1996;18:196.
4. Inman WD, Reed MJ.In-ventors; Shaman Pharmaceuticals, assignee Triterpenoid compound for the treatment of diabetes. US Patent 5, 691, 386. 1997 Nov 25.
5. Gopalakrishnan S, Ismail ST, Begum HV, Elango V. Anti-inflammatory activity of Salaciaoblonga Wall. And Azimatetracantha Lam. J Ethnopharmacol 1997;56:145-52.
6. Naveen A. Hepatoprotective activity of ethanolic extract of root bark of Salacia chinensis. J Pharm Res 2010;3:833-4.
7. Sellamuthu PS, Muniappan BP, Perumal SM, Kandasamy M. Antihyperglycemic effect of mangiferin in streptozotocin induced diabetic rats. J Health Sci 2009;55:206-14.
8. Yoshikawa M, Zhang Y, Wang T, Nakamura S, Matsuda H. New triterpene constituents, foliasalacins A 1-A 4, B 1-B 3, and C, from the leaves of Salacia chinensis. Chem Pharm Bull (Tokyo) 2008;56:915-20. (Pubitemid 351949703)
9. Jansakul C, Jusapalo N, Mahattanadul S. Hypotensive effect of n-butanol extract from stem of Salacia chinensis in rats, ISHS Acta Horticulturae 678: III WOCMAP Congress on Medicinal and Aromatic Plants.Vol. 4. Targeted Screening of Medicinal and Aromatic Plants, Economics and Law.
10. Ministry of Health (India). Pharmacopoeia of India. Government of India; 1982. p. 650, 948.
11. Khandewal KR. Practical Pharmacognosy. 14 th ed. Pune, India: Nirali Prakashan; 2005. p. 146-57.
12. Alam AM, Ahuja A, Baboota S, Gidwani SK, Ali J. Formulation and evaluation of Pharmaceutically equivalent parental depot suspension of methyl prednisolone acetate. Indian J Pharm Sci 2009;71:30-3.
13. Committee for the Purpose of Control and Supervision of Experimental Animals (CPCSEA), OECD Guidelines for the testing of chemicals, revised draft guidelines 423: Acute Oral toxicity-Acute toxic class method, revised document. India: Ministry of Social Justice and Empowerment; 2000.
14. Pande VV, Dubey S. Antihyperlipidemic activity of Sphaeranthus indicus on atherogenic diet induced hyperlipidemia in rats. Int J Green Pharm 2009;3:159-61.
15. Allian CC, Poon LS, Chan CS, Richmond W, Paul CF. Enzymatic determination of total serum cholesterol. Clin Chem 1974;20:470-5.
16. Pari L, Latha M. Effect of Cassia auriculata flowers on blood sugar levels, serum and tissue lipids in streptozotocin diabetic rats. Singapore Med J 2002;43:617-21. (Pubitemid 36307078)
17. Saravana K, Mazumder A, Saravanan VS. Antihyperlipidemic activity of Camellia sinensis leaves in Triton WR-1339 induced albino rats. Pharmacogn Mag 2008;4:60-4.
18. Friedman M, Byers SO. Mechanism underlying hypercholesterolemia induced by triton WR-1339. Am J Physiol 1957;190:439-45.