Apoptosis of the fibrocytes type 1 in the spiral ligament and blood labyrinth barrier disturbance cause hearing impairment in murine cerebral malaria

Malaria Journal

Volumn 11, Issue , 2012, Pages

  Schmutzhard, Joachim ^a   Kositz, Christian H ^a   Glueckert, Rudolf ^a   Schmutzhard, Erich ^a   Schrott Fischer, Annelies ^a   Lackner, Peter ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

Author keywords

Apoptosis; Blood labyrinth barrier; Hearing impairment; Murine cerebral malaria; Spiral ligament fibrocytes

Indexed keywords

CASPASE 3; CONNEXIN 26; GAP JUNCTION PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BLOOD LABYRINTH BARRIER; BRAIN MALARIA; CELLS; CONTROLLED STUDY; DISEASE ASSOCIATION; FIBROCYTE; GANGLION; HEARING IMPAIRMENT; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PERMEABILITY BARRIER; PLASMODIUM BERGHEI INFECTION; SPIRAL LIGAMENT; ANIMAL; C57BL MOUSE; DISEASE MODEL; HEARING LOSS; INNER EAR DISEASE; MALARIA; MICROSCOPY; PATHOLOGY; PATHOPHYSIOLOGY;

ANIMALS; APOPTOSIS; CASPASE 3; CONNEXINS; DISEASE MODELS, ANIMAL; HEARING LOSS; IMMUNOHISTOCHEMISTRY; LABYRINTH DISEASES; MALARIA, CEREBRAL; MICE; MICE, INBRED C57BL; MICROSCOPY; SPIRAL LIGAMENT OF COCHLEA;

EID: 84856382424     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/1475-2875-11-30     Document Type: Article

References (25)

1. WHO Expert Committee on Malaria. WHO, World Health Organ Tech Rep Ser 2008 2008 892 899
2. Persistent neurocognitive impairments associated with severe falciparum malaria in Kenyan children. Carter JA, Mung'ala-Odera V, Neville BG, Murira G, Mturi N, Musumba C, Newton CR, J Neurol Neurosurg Psychiatry 2005 76 476 481 10.1136/jnnp.2004.043893 15774431 (Pubitemid 40486569)
3. Severe falciparum malaria and acquired childhood language disorder. Carter JA, Lees JA, Gona JK, Murira G, Rimba K, Neville BG, Newton CR, Dev Med Child Neurol 2006 48 51 57 16359594 (Pubitemid 43124457)
4. Sensorineural deafness in Tanzanian children-is ototoxicity a significant cause? A pilot study. Freeland A, Jones J, Mohammed NK, Int J Pediatr Otorhinolaryngol 2010 74 516 519 10.1016/j.ijporl.2010.02.010 20227774
5. Severe neurological sequelae and behaviour problems after cerebral malaria in Ugandan children. Idro R, Kakooza-Mwesige A, Balyejjussa S, Mirembe G, Mugasha C, Tugumisirize J, Byarugaba J, BMC Res Notes 2010 3 104 10.1186/1756-0500-3-104 20398391
6. Murine malaria is associated with significant hearing impairment. Schmutzhard J, Kositz CH, Lackner P, Dietmann A, Fischer M, Glueckert R, Reindl M, Stephan K, Riechelmann H, Schrott-Fischer A, Schmutzhard E, Malar J 2010 9 159 10.1186/1475-2875-9-159 20540722
7. Murine cerebral malaria: histopathology and ICAM 1 immunohistochemistry of the inner ear. Schmutzhard J, Kositz CH, Lackner P, Pritz C, Glueckert R, Fischer M, Schmutzhard E, Schrott-Fischer A, Trop Med Int Health 2011 doi:10.1111/j.1365-3156.2011.02801.x
8. Gap junction systems in the mammalian cochlea. Kikuchi T, Kimura RS, Paul DL, Takasaka T, Adams JC, Brain Res Brain Res Rev 2000 32 163 166 10751665 (Pubitemid 30177319)
9. Gap junctions in the inner ear: comparison of distribution patterns in different vertebrates and assessement of connexin composition in mammals. Forge A, Becker D, Casalotti S, Edwards J, Marziano N, Nevill G, J Comp Neurol 2003 467 207 231 10.1002/cne.10916 14595769 (Pubitemid 37363146)
10. Connexin-26 mutations in deafness and skin disease. Lee JR, White TW, Expert Rev Mol Med 2009 11 35 19939300
11. Determination of the expression of lymphocyte surface markers and cytokine levels in a mouse model of Plasmodium berghe. Dogruman-Al F, Fidan I, Kustimur S, Ceber K, Imir T, New Microbiol 2009 32 285 291 19845111
12. Effect of proinflammatory cytokines on cultured spiral ligament fibrocytes. Yoshida K, Ichimiya I, Suzuki M, Mogi G, Hear Res 1999 137 155 159 10.1016/S0378-5955(99)00134-3 10545642 (Pubitemid 29505322)
13. Does perinatal asphyxia induce apoptosis in the inner ear? Schmutzhard J, Glueckert R, Sergi C, Schwentner I, Abraham I, Schrott-Fischer A, Hear Res 2009 250 1 9 10.1016/j.heares.2008.12.006 19136052
14. Activation of caspase-3 is associated with oxidative stress in the hydropic guinea pig cochlea. Labbe D, Teranishi MA, Hess A, Bloch W, Michel O, Hear Res 2005 202 21 27 10.1016/j.heares.2004.10.002 15811695 (Pubitemid 40476093)
15. Morphological correlates of acute and permanent hearing loss during experimental pneumococcal meningitis. Klein M, Koedel U, Pfister HW, Kastenbauer S, Brain Pathol 2003 13 123 132 12744466 (Pubitemid 36460813)
16. Altered cochlear fibrocytes in a mouse model of DFN3 nonsyndromic deafness. Minowa O, Ikeda K, Sugitani Y, Oshima T, Nakai S, Katori Y, Suzuki M, Furukawa M, Kawase T, Zheng Y, Ogura M, Asada Y, Watanabe K, Yamanaka H, Gotoh S, Nishi-Takeshima M, Sugimoto T, Kikuchi T, Takasaka T, Noda T, Science 1999 285 1408 1411 10.1126/science.285.5432.1408 10464101 (Pubitemid 29411674)
17. Cloned lines of Plasmodium berghe ANKA differ in their abilities to induce experimental cerebral malaria. Amani V, Boubou MI, Pied S, Marussig M, Walliker D, Mazier D, Renia L, Infect Immun 1998 66 4093 4099 9712753 (Pubitemid 28402677)
18. Age-related susceptibility and resistance to Plasmodium berghe in mice and rats. Pierrot C, Adam E, Lafitte S, Godin C, Dive D, Capron M, Khalife J, Exp Parasitol 2003 104 81 85 10.1016/S0014-4894(03)00134-6 12932766 (Pubitemid 41123193)
19. Behavioural and histopathological alterations in mice with cerebral malaria. Lackner P, Beer R, Heussler V, Goebel G, Rudzki D, Helbok R, Tannich E, Schmutzhard E, Neuropathol Appl Neurobiol 2006 32 177 188 10.1111/j.1365-2990. 2006.00706.x 16599946
20. A protocol for cryoembedding the adult guinea pig cochlea for fluorescence immunohistology. Coleman B, Rickard NA, de Silva MG, Shepherd RK, J Neurosci Methods 2009 176 144 151 10.1016/j.jneumeth.2008.09.007 18835298
21. Lateral wall histopathology and endocochlear potential in the noise-damaged mouse cochlea. Hirose K, Liberman MC, J Assoc Res Otolaryngol 2003 4 339 352 10.1007/s10162-002-3036-4 14690052 (Pubitemid 37187813)
22. Apoptosis in experimental cerebral malaria: spatial profile of cleaved caspase-3 and ultrastructural alterations in different disease stages. Lackner P, Burger C, Pfaller K, Heussler V, Helbok R, Morandell M, Broessner G, Tannich E, Schmutzhard E, Beer R, Neuropathol Appl Neurobiol 2007 33 560 571 17442059 (Pubitemid 47390077)
23. Neuronal apoptosis, metallothionein expression and proinflammatory responses during cerebral malaria in mice. Wiese L, Kurtzhals JA, Penkowa M, Exp Neurol 2006 200 216 226 10.1016/j.expneurol.2006.02.011 16624296 (Pubitemid 44097022)
24. Blood-brain barrier breakdown during cerebral malaria: suicide or murder? Pino P, Taoufiq Z, Nitcheu J, Vouldoukis I, Mazier D, Thromb Haemost 2005 94 336 340 16113823 (Pubitemid 41122488)
25. Inflammatory signals increase Fas ligand expression by inner ear cells. Bodmer D, Brors D, Pak K, Keithley EM, Mullen L, Ryan AF, Gloddek B, J Neuroimmunol 2002 129 10 17 10.1016/S0165-5728(02)00143-1 12161015 (Pubitemid 34879088)