Extreme lactic acidosis type B associated with metformin treatment

NDT Plus

Volumn 4, Issue 6, 2011, Pages 399-401

  Pikwer, Andreas ^a   Vernersson, Einar ^a   Frid, Anders ^a   Sterner, Gunnar ^b  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b LUND UNIVERSITY   (Sweden)

Author keywords

Lactic acidosis; Metformin

Indexed keywords

ATENOLOL; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BICARBONATE; CALCIUM CHLORIDE; CREATININE; DOBUTAMINE; INFUSION FLUID; LACTIC ACID; LOOP DIURETIC AGENT; METFORMIN; NORADRENALIN; RAMIPRIL; REPAGLINIDE; SIMVASTATIN;

ACUTE KIDNEY FAILURE; ADULT; ARTERIAL BLOOD; ARTERIAL PRESSURE; ARTICLE; BREATHING RATE; CARBON DIOXIDE TENSION; CASE REPORT; CONTINUOUS RENAL REPLACEMENT THERAPY; CREATININE BLOOD LEVEL; DIABETIC PATIENT; DRUG BLOOD LEVEL; DRUG ELIMINATION; DRUG HALF LIFE; DRUG WITHDRAWAL; ELECTROCARDIOGRAPHY; EMERGENCY CARE; ENDOTRACHEAL INTUBATION; FATIGUE; FEMALE; GLASGOW COMA SCALE; GLOMERULUS FILTRATION RATE; HEART RATE; HEMODIAFILTRATION; HUMAN; INTENSIVE CARE UNIT; LACTATE BLOOD LEVEL; LACTIC ACIDOSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; OXYGEN TENSION; PH; PRIORITY JOURNAL; SOMNOLENCE; T WAVE; TREATMENT WITHDRAWAL; VOMITING;

EID: 84856361254     PISSN: 17530784     EISSN: 17530792     Source Type: Journal    
DOI: 10.1093/ndtplus/sfr110     Document Type: Article

References (7)

1. Frid A, Sterner GN, Londahl M et al. Novel assay of metformin levels in patients with type 2 diabetes and varying levels of renal function: clinical recommendations. Diabetes Care 2010; 33: 1291-1293
2. Lemyze M, Baudry JF, Collet F et al. Life threatening lactic acidosis. BMJ 2010; 340: c857
3. Bagshaw SM, Delaney A, HaaseMet al. Loop diuretics in the management of acute renal failure: a systematic review and meta-analysis. Crit Care Resusc 2007; 9: 60-68
4. Heaney D, Majid A, Junor B. Bicarbonate haemodialysis as a treatment of metformin overdose. Nephrol Dial Transplant 1997; 12: 1046-1047 (Pubitemid 27216337)
5. Kraut JA, Madias NE. Metabolic acidosis: pathophysiology, diagnosis and management. Nat Rev Nephrol 2010; 6: 274-285
6. Peters N, Jay N, Barraud D et al. Metformin-associated lactic acidosis in an intensive care unit. Crit Care 2008; 12: R149
7. Chang CT, Chen YC, Fang JT et al. High anion gap metabolic acidosis in suicide: don't forget metformin intoxication-two patients' experiences. Ren Fail 2002; 24: 671-675