Validated LC-MS/MS method for quantification of agomelatine in human plasma and its application in a pharmacokinetic study

Journal of Mass Spectrometry

Volumn 47, Issue 1, 2012, Pages 23-28

  Patil, Satish R ^a,b   Nerurkar, Ketan K ^b   Kalamkar, Ashok M ^b   Pukale, Vishwas ^a,b   Mangaonkar, Kiran V ^c   Pingale, Satish G ^c  

^a NMIMS UNIVERSITY   (India)

^b Drug Monitoring Research Institute   (India)

^c INSTITUTE OF SCIENCE   (India)

Author keywords

agomelatine; human plasma; liquid liquid extraction; pharmacokinetic study; tandem mass spectrometry

Indexed keywords

AGOMELATINE; HUMAN PLASMAS; LIQUID-LIQUID EXTRACTION; PHARMACOKINETIC STUDY; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS; PLASMA (HUMAN); PLASMAS; SOLVENT EXTRACTION;

LIQUIDS;

AGOMELATINE; FLUOXETINE;

ACCURACY; ARTICLE; BLOOD SAMPLING; DRUG BLOOD LEVEL; DRUG DETERMINATION; HUMAN; IONIZATION; LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY TANDEM MASS SPECTROMETRY; LIQUID LIQUID EXTRACTION; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SEPARATION TECHNIQUE; TANDEM MASS SPECTROMETRY; VALIDATION STUDY;

ACETAMIDES; AREA UNDER CURVE; CHROMATOGRAPHY, LIQUID; FLUOXETINE; HUMANS; LEAST-SQUARES ANALYSIS; LIQUID-LIQUID EXTRACTION; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 84856348695     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.2020     Document Type: Article

References (6)

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