O-glycoproteomics: Site-specific O-glycoprotein analysis by CID/ETD electrospray ionization tandem mass spectrometry and top-down glycoprotein Sequencing by In-Source Decay MALDI Mass Spectrometry

Methods in Molecular Biology

Volumn 842, Issue , 2012, Pages 179-189

  Hanisch, Franz Georg ^a  

^a UNIVERSITY OF COLOGNE   (Germany)

Author keywords

Electron transfer dissociation; ESI mass spectrometry; Glycopeptides; MALDI in source decay; Mucin; Mucin type O glycosylation; O glycans

Indexed keywords

GLYCOPROTEIN;

ARTICLE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; GLYCOBIOLOGY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NANOTECHNOLOGY; TANDEM MASS SPECTROMETRY;

CHROMATOGRAPHY, LIQUID; GLYCOMICS; GLYCOPROTEINS; NANOTECHNOLOGY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TANDEM MASS SPECTROMETRY;

EID: 84856330250     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-513-8_10     Document Type: Article

References (19)

1. Geyer, H., Geyer, R. (2006) Strategies for analysis of glycoprotein glycosylation. Biochim. Biophys. Acta 1764, 1853-1869
2. Wuhrer, M., Catalina, M.I., Deelder, A.M., Hokke, C.H. (2007) Glycoproteomics based on tandem mass spectrometry of glycopeptides. J. Chromatogr. B 849, 115-128
3. Tarp, M.A., Clausen, H. (2008) Mucin-type O-glycosylation and its potential use in drug and vaccine development. Biochim. Biophys. Acta 1780, 546-563
4. Rademaker, G.J., Pergantis, S.A., Blok-Tip, L., Langridge, J.I., Kleen, A., Thomas-Oates, J.E. (1998) Mass spectrometric determination of the sites of O-glycan attachment with low picomolar sensitivity. Anal. Biochem. 257, 149-160
5. Hanisch, F.-G., Jovanovic, M., Peter-Katalinic, J. (2001) Glycoprotein identification and localization of O-glycosylation sites by mass spectrometric analysis of deglycosylated/alkylaminylated peptide fragments. Anal. Biochem. 290, 47-59
6. Mirgorodskaya, E., Hassan, H., Clausen, H., Roepstorff, P. (2001) Anal. Chem. 73, 1263-1269
7. Zheng, Y., Guo, Z., Cai, Z. (2009) Combination of beta-elimination and liquid chromatography/ quadrupole time-of-flight mass spectrometry for the determination of O-glycosylation sites. Talanta 78, 358-363
8. Wells, L., Vosseller, K., Cole, R.N., Cronshaw, J.M., Matunis, M.J., Hart, G.W. (2002) Mapping sites of O-GlcNAc modification using affinity tags for serine and threonine post-translational modifications. Mol. Cell Proteomics 1, 791-804
9. Mirgorodskaya, E., Hassan, H., Wandall, H.H., Clausen, H., Roepstorff, P. (1999) Partial vapor-phase hydrolysis of peptide bonds: A method for mass spectrometric determination of O-glycosylated sites in glycopeptides. Anal. Biochem. 269, 54-65
10. Goletz, S., Thiede, B., Hanisch, F.-G., Schultz, M., Peter-Katalinic, J., Müller, S., Seitz, O., Karsten, U. (1997) A sequencing strategy for the localization of O-glycosylation sites of MUC1 tandem repeats by PSD MALDI mass spectrometry. Glycobiology 7, 881-896
11. Hanisch, F.-G., Green, B.N., Bateman, R., Peter-Katalinic, J. (1998) Localization of O-glycosylation sites of MUC1 tandem repeats by QTOF mass spectrometry. J. Mass Spectrom. 33, 358-362
12. Hogan, J.M., Pitteri, S.J., Chrisman, P.A., McLuckey, S.A. (2005) Complementary structural information from a tryptic N-linked glycopeptide via electron transfer ion/ion reactions and collision-induced dissociation. J. Proteome Res. 4, 628-632
13. Darula, Z., Chalkley, R.J., Baker, P., Burlingame, A.L., Medzihradszky, K.F. (2010) Mass spectrometric analysis, automated identification and complete annotation of O-linked glycopeptides. Eur. J. Mass Spectrom. 16, 421-428
14. Brown, R., Lennon, J.J. (1995) Sequence-specific fragmentation of matrix-assisted laser-desorbed protein/peptide ions. Anal. Chem. 67, 3990-3999
15. Suckau, D., Cornett, D.S. (1998) Protein sequencing by ISD and PSD MALDI-TOF MS Anal. Mag. 26, 18-21
16. Suckau, D., Resemann, A. (2003) T3-sequencing: Targeted characterization of the N- and C-termini of undigested proteins by mass spectrometry. Anal. Chem. 75, 5817-5824
17. Resemann, A., Wunderlich, D., Rothbauer, U., Warscheid, B., Leonhardt, H., Fuchser, J., Kuhlmann, K., Suckau, D. (2010) Top-down de novo protein sequencing of a 13.6 kDa camelid single heavy chain antibody by matrix-assisted laser desorption ionization-time-of-flight/time-of-flight mass spectrometry. Anal. Chem. 82, 3283-3292
18. Resemann, A., Suckau, D. (2009) Automated acquisition of MALDI-ISD spectra for the Nand C-terminal sequence determination of intact proteins, Bruker Daltonics, Technical Note #TN-36
19. Hanisch, F.-G. (2011) Top-down sequencing of O-glycoproteins by in-source-decay matrixassisted laser desorption ionization mass spectrometry for glycosylation site analysis. Anal. Chem. 83, 4829-4837