Brain Chondroitin/dermatan sulfate, from cerebral tissue to fine structure: Extraction, preparation, and fully automated chip-electrospray mass spectrometric analysis

Methods in Molecular Biology

Volumn 836, Issue , 2012, Pages 145-159

  Zamfir, Alina D ^a   Flangea, Corina ^a,b   Serb, Alina ^c   Sisu, Eugen ^c   Zagrean, Leon ^d   Rizzi, Andreas ^e   Seidler, Daniela G ^f  

^a AUREL VLAICU UNIVERSITY OF ARAD   (Romania)

^b WEST UNIVERSITY OF TIMISOARA   (Romania)

^c VICTOR BABES UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^d CAROL DAVILA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^e UNIVERSITY OF VIENNA   (Austria)

^f UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

Cerebral tissue; Chip nanoelectrospray; Chondroitin sulfate; Dermatan sulfate; Glycosaminoglycan; Multistage mass spectrometry

Indexed keywords

CHONDROITIN; DERMATAN SULFATE;

ANIMAL; ARTICLE; BRAIN; BRAIN LEVEL; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; ISOLATION AND PURIFICATION; METABOLISM;

ANIMALS; BRAIN; BRAIN CHEMISTRY; CHONDROITIN; DERMATAN SULFATE; HUMANS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

MAMMALIA;

EID: 84856320012     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-498-8_10     Document Type: Article

References (26)

1. Bielik, A. M. and Zaia J. (2010) Extraction of Chondroitin/Dermatan Sulfate Glycosaminoglycans from Connective Tissue for Mass Spectrometric Analysis. Methods Mol. Biol. 600 , 215-225.
2. Sisu, E.; Flangea, C.; Serb, A.; Zamfi r, A. D. (2011) Modern developments in mass spectrometry of chondroitin and dermatan sulfate glycosaminoglycans. Amino Acids. 41 , 235-256.
3. Nielsen, T.C.; Meikle, P.J.; Hopwood, J.J.; Fuller, M. (2008) Minimum substrate requirements of endoglycosidase activities toward dermatan sulfate by electrospray ionization-tandem mass spectrometry. Glycobiology. 18 , 1119-1128. (Pubitemid 352762846)
4. Zamfi r, A. D.; Flangea, C.; Sisu, E.; Serb, A. F.; Dinca, N.; Bruckner, P.; Seidler, D. G. (2009) Analysis of novel over-and under-sulfated glycosaminoglycan sequences by enzyme cleavage and multiple stage MS. Proteomics. 9 , 3435-3444.
5. Zamfi r, A. D.; Seidler, D.; Kresse, H.; Peter-Katalinic, J. (2003) Structural investigation of chondroitin/dermatan sulfate oligosaccharides from human skin fibroblast decorin. Glycobiology. 11 , 733-742. (Pubitemid 37407102)
6. Zamfir, A. D.; Seidler, D.; Schonherr, E.; Kresse, H.; Peter-Katalini, J. (2004) On-line sheathless capillary electrophoresis/nanoelectrospray ionization-tandem mass spectrometry for the analysis of glycosaminoglycan oligosaccharides. Electrophoresis. 25 , 2010-2016. (Pubitemid 39136321)
7. Flangea, C.; Schiopu, C.; Sisu, E.; Serb, A.; Przybylski, M.; Seidler, D. G.; Zamfi r, A. D. (2009) Determination of sulfation pattern in brain glycosaminoglycans by chip-based electrospray ionization ion trap mass spectrometry. Anal. Bioanal. Chem. 395 , 2489-2498.
8. Seidler, D. G.; Peter-Katalini, J.; Zamfi r, A. D. (2007) Galactosaminoglycan function and oligosaccharide structure determination Scient. World J. 19 , 233-241. (Pubitemid 46294535)
9. Bao, X.; Muramatsu, T.; Sugahara, K. (2005) Demonstration of the Pleiotrophinbinding oligosaccharide sequences isolated from chondroitin sulfate/dermatan sulfate hybrid chains of embryonic pig brains. J. Biol. Chem. 280 , 35318-35328. (Pubitemid 41532720)
10. Purushothaman, A.; Fukuda, J.; Mizumoto, S.; ten Dam, G. B.; van Kuppevelt, T. H.; Kitagawa, et al. (2007) Functions of chondroitin sulfate/dermatan sulfate chains in brain development. Critical roles of E and iE disaccharide units recognized by a single chain antibody GD3G7. J. Biol. Chem. 282 , 19442-19452. (Pubitemid 47100083)
11. Amon, S.; Zamfi r, A. D.; Rizzi, A. (2008) Glycosylation analysis of glycoproteins and proteoglycans using capillary electrophoresismass spectrometry strategies. Electrophoresis. 29 , 2485-2507. (Pubitemid 351911877)
12. Volpi, N.; Maccari, F.; Linhardt, R. J. (2008) Capillary electrophoresis of complex natural polysaccharides. Electrophoresis. 29 , 3095-3106.
13. Zaia, J. (2009) On-line separations combined with MS for analysis of glycosaminoglycans. Mass Spectrom. Rev. 28 , 254-272.
14. Zamfi r, A. D.; Flangea, C.; Altmann, F.; Rizzi, A. M. (2010) Glycosylation analysis of proteins, proteoglycans and glycolipids by CE-MS. Adv. Chromatogr. 49 , 135-194.
15. Zamfi r, A. D.; Seidler, D.; Kresse, H.; Peter-Katalinic, J. (2002) Structural characterization of chondroitin/dermatan sulfate oligosaccharides from bovine aorta by capillary electrophoresis and electrospray ionization quadrupole time-of-fl ight tandem mass spectrometry. Rapid Commun. Mass Spectrom. 16 , 2015-2024. (Pubitemid 35257108)
16. Flangea, C.; Serb, A. F.; Schiopu, C.; Tudor, S.; Sisu, E.; Seidler, D. G.; Zamfi r, A. D. (2009) Discrimination of GalNAc (4S/6S) sulfation sites in chondroitin sulfate disaccharides by chip-based nanoelectrospray multistage mass spectrometry. Cent. Eur. J. Chem. 7 , 752-759.
17. Miller, M. J. C.; Costello, C. E.; Malmström, A.; Zaia, J. (2006) A tandem mass spectrometric approach to determination of chondroitin/dermatan sulfate oligosaccharide glycoforms. Glycobiology. 16 , 502-513. (Pubitemid 43779046)
18. Wolff, J. J.; Laremore, T. N.; Busch, A. M.; Linhardt, R. J.; Amster, I. J. (2008) Electron detachment dissociation of dermatan sulfate oligosaccharides. J. Am. Soc. Mass Spectrom. 19 , 294-304. (Pubitemid 351249130)
19. Hitchcock, A. M.; Yates, K. E.; Costello, C. E.; Zaia, J. (2008) Comparative glycomics of connective tissue glycosaminoglycans. Proteomics. 8 , 1384-1397. (Pubitemid 351518550)
20. McClellan, J. E.; Costello, C. E.; OConnor, P. B.; Zaia, J. (2002) Influence of charge state on product ion mass spectra and the determination of 4S/6S sulfation sequence of chondroitin sulfate oligosaccharides. Anal. Chem. 74 , 3760-3771. (Pubitemid 34855869)
21. Zaia, J.; Miller, M. J. C.; Seymour, J. L.; Costello, C. E. (2007) The role of mobile protons in negative ion CID of oligosaccharides. J Am Soc Mass Spectrom. 18 , 952-960. (Pubitemid 46617286)
22. Zaia, J. and Costello, C. E. (2001) Compositional analysis of glycosaminoglycans by ESI-MS. Anal. Chem. 73 , 233-239.
23. Seidler, D. G.; Breuer, E.; Grande-Allen, K. J.; Hascall, V. C.; Kresse, H. (2002) Core protein dependence of epimerization of glucuronosyl residues in galactosaminoglycans. J.Biol.Chem. 277 , 42409-42416. (Pubitemid 35264601)
24. Gu, K.; Linhardt, R. J.; Laliberte, M.; Gu, K.; Zimmermann, J. (1995) Purification, characterization and specificity of chondroitin lyases and glucuronidase from Flavobacterium heparinum. Biochem. J. 312 , 569-577. (Pubitemid 26002227)
25. Zaia, J. (2004) Mass spectrometry of oligosaccharides. Mass Spectrom. Rev. 23 , 161-227.
26. Almeida, R.; Mosoarca, C.; Chirita, M.; Udrescu, V.; Dinca, N.; Vukelic, Z.; et al. (2008) Coupling of fully automated chip-based electrospray ionization to high-capacity ion trap mass spectrometer for ganglioside analysis. Anal. Biochem. 378 , 43-52.