-
1
-
-
79960453276
-
EASL Clinical Practice Guidelines: Management of hepatitis C virus infection
-
European Association for the Study of the Liver
-
European Association for the Study of the Liver. EASL Clinical Practice Guidelines: management of hepatitis C virus infection. J Hepatol 2011;55:245-64
-
(2011)
J Hepatol
, vol.55
, pp. 245-264
-
-
-
2
-
-
68249154875
-
Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection
-
McHutchison J, Lawitz E, Shiffman M, et al. Peginterferon alfa-2b or alfa-2a with ribavirin for treatment of hepatitis C infection. N Engl J Med 2009;361:580-93
-
(2009)
N Engl J Med
, vol.361
, pp. 580-593
-
-
McHutchison, J.1
Lawitz, E.2
Shiffman, M.3
-
3
-
-
1542378867
-
Peginterferon-alpha 2a and ribavirin combination therapy in chronic hepatitis C: A randomized study of treatment duration and ribavirin dose
-
Hadziyannis S, Sette H, Morgan T, et al. Peginterferon-alpha 2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose. Ann Intern Med 2004;140:346-55
-
(2004)
Ann Intern Med
, vol.140
, pp. 346-355
-
-
Hadziyannis, S.1
Sette, H.2
Morgan, T.3
-
4
-
-
79953173221
-
Boceprevir for untreated chronic HCV genotype 1 infection
-
Poordad F, McCone J, Bacon B, et al. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med 2011;364:1195-206
-
(2011)
N Engl J Med
, vol.364
, pp. 1195-1206
-
-
Poordad, F.1
McCone, J.2
Bacon, B.3
-
5
-
-
79953176289
-
Boceprevir for previously treated chronic HCV genotype 1 infection
-
Bacon B, Gordon S, Lawitz E, et al. Boceprevir for previously treated chronic HCV genotype 1 infection. N Engl J Med 2011;364:1207-17
-
(2011)
N Engl J Med
, vol.364
, pp. 1207-1217
-
-
Bacon, B.1
Gordon, S.2
Lawitz, E.3
-
6
-
-
79959381354
-
Telaprevir for retreatment of HCV infection
-
Zeuzem S, Andreone P, Pol S, et al. Telaprevir for retreatment of HCV infection. N Engl J Med 2011;364:2417-28
-
(2011)
N Engl J Med
, vol.364
, pp. 2417-2428
-
-
Zeuzem, S.1
Andreone, P.2
Pol, S.3
-
7
-
-
79959438789
-
Telaprevir for previously untreated chronic hepatitis C virus infection
-
Jacobson I, McHutchison J, Dusheiko G, et al. Telaprevir for previously untreated chronic hepatitis C virus infection. N Engl J Med 2011;364:2405-16
-
(2011)
N Engl J Med
, vol.364
, pp. 2405-2416
-
-
Jacobson, I.1
McHutchison, J.2
Dusheiko, G.3
-
8
-
-
79960444768
-
Directly acting antivirals against hepatitis C virus
-
Soriano V, Vispo E, Poveda E, et al. Directly acting antivirals against hepatitis C virus. J Antimicrob Chemother 2011;66:1673-86.
-
(2011)
J Antimicrob Chemother
, vol.66
, pp. 1673-1686
-
-
Soriano, V.1
Vispo, E.2
Poveda, E.3
-
9
-
-
34248592912
-
Care of patients coinfected with HIV and hepatitis C virus: 2007 Updated recommendations from the HCV-HIV International Panel
-
DOI 10.1097/QAD.0b013e3281084e4d, PII 0000203020070531000001
-
Soriano V, Puoti M, Sulkowski M, et al. Care of patients coinfected with HIV and hepatitis C virus: 2007 updated recommendations from the HCV-HIV International Panel. AIDS 2007;21:1073-89 (Pubitemid 46763278)
-
(2007)
AIDS
, vol.21
, Issue.9
, pp. 1073-1089
-
-
Soriano, V.1
Puoti, M.2
Sulkowski, M.3
Cargnel, A.4
Benhamou, Y.5
Peters, M.6
Mauss, S.7
Brau, N.8
Hatzakis, A.9
Pol, S.10
Rockstroh, J.11
-
11
-
-
70349292099
-
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance
-
Ge D, Fellay J, Thompson A, et al. Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance. Nature 2009;461:399-401
-
(2009)
Nature
, vol.461
, pp. 399-401
-
-
Ge, D.1
Fellay, J.2
Thompson, A.3
-
12
-
-
70349533037
-
Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C
-
Tanaka Y, Nishida N, Sugiyama M, et al. Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C. Nat Genet 2009;41:1105-9
-
(2009)
Nat Genet
, vol.41
, pp. 1105-1109
-
-
Tanaka, Y.1
Nishida, N.2
Sugiyama, M.3
-
13
-
-
70349548852
-
IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy
-
Suppiah V, Moldovan M, Ahlenstiel G, et al. IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapy. Nat Genet 2009;41:1100-4
-
(2009)
Nat Genet
, vol.41
, pp. 1100-1104
-
-
Suppiah, V.1
Moldovan, M.2
Ahlenstiel, G.3
-
14
-
-
77949831342
-
Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: A genome-wide association study
-
Rauch A, Kutalik Z, Descombes P, et al. Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association study. Gastroenterology 2010;138:1338-45
-
(2010)
Gastroenterology
, vol.138
, pp. 1338-1345
-
-
Rauch, A.1
Kutalik, Z.2
Descombes, P.3
-
15
-
-
77951880384
-
Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients
-
Rallon N, Naggie S, Benito JM, et al. Association of a single nucleotide polymorphism near the interleukin-28B gene with response to hepatitis C therapy in HIV/hepatitis C virus-coinfected patients. AIDS 2010;24:F23-9.
-
(2010)
AIDS
, vol.24
-
-
Rallon, N.1
Naggie, S.2
Benito, J.M.3
-
16
-
-
79953198245
-
A new era of hepatitis C therapy begins
-
Jensen D. A new era of hepatitis C therapy begins. N Engl J Med 2011;364:1272-4
-
(2011)
N Engl J Med
, vol.364
, pp. 1272-1274
-
-
Jensen, D.1
-
17
-
-
34247895578
-
The Hepatitis C Virus Life Cycle as a Target for New Antiviral Therapies
-
DOI 10.1053/j.gastro.2007.03.116, PII S0016508507006427
-
Pawlotsky JM, Chevaliez S, McHutchison J. The hepatitis C virus life cycle as a target for new antiviral therapies. Gastroenterology 2007;132:1979-98 (Pubitemid 46695724)
-
(2007)
Gastroenterology
, vol.132
, Issue.5
, pp. 1979-1998
-
-
Pawlotsky, J.1
Chevaliez, S.2
McHutchison, J.G.3
-
18
-
-
79959401302
-
Natural polymorphisms associated with resistance to new antivirals against hepatitis C virus (HCV) in newly diagnosed HIV/HCV-coinfected patients in Spain
-
Trevino A, de Mendoza C, Parra P, et al. Natural polymorphisms associated with resistance to new antivirals against hepatitis C virus (HCV) in newly diagnosed HIV/HCV-coinfected patients in Spain. Antivir Ther 2011;16:413-16
-
(2011)
Antivir Ther
, vol.16
, pp. 413-416
-
-
Trevino, A.1
De Mendoza, C.2
Parra, P.3
-
19
-
-
78149434641
-
DEB-025 (alisporivir) inhibits HCV replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A
-
Coelmont L, Hanoulle X, Chatterji U, et al. DEB-025 (alisporivir) inhibits HCV replication by preventing a cyclophilin A induced cis-trans isomerisation in domain II of NS5A. PLoS One 2010;5:e13687
-
(2010)
PLoS One
, vol.5
-
-
Coelmont, L.1
Hanoulle, X.2
Chatterji, U.3
-
20
-
-
80052826527
-
Response-guided telaprevir combination treatment for hepatitis C virus infection
-
Sherman K, Flamm S, Afdhal N, et al. Response-guided telaprevir combination treatment for hepatitis C virus infection. N Engl J Med 2011;365:1014-24
-
(2011)
N Engl J Med
, vol.365
, pp. 1014-1024
-
-
Sherman, K.1
Flamm, S.2
Afdhal, N.3
-
21
-
-
79251554986
-
Telaprevir is effective given every 8 or 12 hours with ribavirin and peginterferon alfa-2a or 2b to patients with chronic hepatitis C
-
Marcellin P, Forns X, Goeser T, et al. Telaprevir is effective given every 8 or 12 hours with ribavirin and peginterferon alfa-2a or 2b to patients with chronic hepatitis C. Gastroenterology 2011;140:459-68
-
(2011)
Gastroenterology
, vol.140
, pp. 459-468
-
-
Marcellin, P.1
Forns, X.2
Goeser, T.3
-
22
-
-
80052955087
-
Relationship between adherence to HCV therapy and virologic outcomes: A cohort study
-
Lo Re III V, Teal V, Localio R, et al. Relationship between adherence to HCV therapy and virologic outcomes: a cohort study. Ann Intern Med 2011;155:353-60
-
(2011)
Ann Intern Med
, vol.155
, pp. 353-360
-
-
Lo Re Iii, V.1
Teal, V.2
Localio, R.3
-
23
-
-
84855935309
-
The critical role of medication adherence in the success of boceprevir and telaprevir in clinical practice
-
press
-
Weiss J, Alcorn M, Rabkin J, Dieterich D. The critical role of medication adherence in the success of boceprevir and telaprevir in clinical practice. J Hepatol 2012; In press
-
(2012)
J Hepatol
-
-
Weiss, J.1
Alcorn, M.2
Rabkin, J.3
Dieterich, D.4
-
24
-
-
80855137985
-
Challenges and opportunities for hepatitis C drug development in HIV-HCV coinfected patients
-
Soriano V, Sherman K, Rockstroh J, et al. Challenges and opportunities for hepatitis C drug development in HIV-HCV coinfected patients. AIDS 2011;25:2197-208.
-
(2011)
AIDS
, vol.25
, pp. 2197-2208
-
-
Soriano, V.1
Sherman, K.2
Rockstroh, J.3
-
25
-
-
77953501710
-
New directly acting antivirals for hepatitis C: Potential for interaction with antiretrovirals
-
Seden K, Back D, Shoo S. New directly acting antivirals for hepatitis C: potential for interaction with antiretrovirals. J Antimicrob Chemother 2010;65:1079-85
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 1079-1085
-
-
Seden, K.1
Back, D.2
Shoo, S.3
-
26
-
-
84856252248
-
Predicted challenges using direct acting antivirals in the current HIV-HCV coinfected population in Spain
-
press
-
Poveda E, Vispo E, Barreiro P, et al. Predicted challenges using direct acting antivirals in the current HIV-HCV coinfected population in Spain. Antivir Ther 2012; In press
-
(2012)
Antivir Ther
-
-
Poveda, E.1
Vispo, E.2
Barreiro, P.3
-
27
-
-
79957448889
-
Second-phase hepatitis C virus RNA decline during telaprevir-based therapy increases with drug effectiveness: Implications for treatment duration
-
Guedj J, Perelson A. Second-phase hepatitis C virus RNA decline during telaprevir-based therapy increases with drug effectiveness: implications for treatment duration. Hepatology 2011;53:1801-8
-
(2011)
Hepatology
, vol.53
, pp. 1801-1808
-
-
Guedj, J.1
Perelson, A.2
-
28
-
-
0036306528
-
Duration and fitness dependence of quasispecies memory
-
DOI 10.1006/jmbi.2001.5232
-
Ruiz-Jarabo C, Arias A, Molina-Paris C, et al. Duration and fitness dependence of quasispecies memory. J Mol Biol 2002;315:285-96 (Pubitemid 34729340)
-
(2002)
Journal of Molecular Biology
, vol.315
, Issue.3
, pp. 285-296
-
-
Ruiz-Jarabo, C.M.1
Arias, A.2
Molina-Paris, C.3
Briones, C.4
Baranowski, E.5
Escarmis, C.6
Domingo, E.7
-
29
-
-
45749088957
-
Why are there different dynamics in the selection of drug resistance in HIV and hepatitis B and C viruses?
-
DOI 10.1093/jac/dkn175
-
Soriano V, Perelson A, Zoulim F. Why different dynamics of selection of drug resistance in HIV, hepatitis B and C viruses? J Antimicrob Chemother 2008;62:1-4 (Pubitemid 351865869)
-
(2008)
Journal of Antimicrobial Chemotherapy
, vol.62
, Issue.1
, pp. 1-4
-
-
Soriano, V.1
Perelson, A.S.2
Zoulim, F.3
-
30
-
-
34247594930
-
Dynamic Hepatitis C Virus Genotypic and Phenotypic Changes in Patients Treated With the Protease Inhibitor Telaprevir
-
DOI 10.1053/j.gastro.2007.02.037, PII S0016508507003940
-
Sarrazin C, Kieffer T, Bartels D, et al. Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir. Gastroenterology 2007;132:1767-77 (Pubitemid 46677938)
-
(2007)
Gastroenterology
, vol.132
, Issue.5
, pp. 1767-1777
-
-
Sarrazin, C.1
Kieffer, T.L.2
Bartels, D.3
Hanzelka, B.4
Muh, U.5
Welker, M.6
Wincheringer, D.7
Zhou, Y.8
Chu, H.9
Lin, C.10
Weegink, C.11
Reesink, H.12
Zeuzem, S.13
Kwong, A.D.14
-
31
-
-
42949167169
-
The hepatitis C virus replicon presents a higher barrier to resistance to nucleoside analogs than to nonnucleoside polymerase or protease inhibitors
-
DOI 10.1128/AAC.01317-07
-
McCown M, Rajyaguru S, Le Pogam S, et al. The hepatitis C virus replicon presents a higher barrier to resistance to nucleoside analogs than to nonnucleoside polymerase or protease inhibitors. Antimicrob Agents Chemother 2008;52:1604-12 (Pubitemid 351614649)
-
(2008)
Antimicrobial Agents and Chemotherapy
, vol.52
, Issue.5
, pp. 1604-1612
-
-
McCown, M.F.1
Rajyaguru, S.2
Le Pogam, S.3
Ali, S.4
Jiang, W.-R.5
Kang, H.6
Symons, J.7
Cammack, N.8
Najera, I.9
-
32
-
-
75149151884
-
Resistance to direct antiviral agents in patients with hepatitis C virus infection
-
Sarrazin C, Zeuzem S. Resistance to direct antiviral agents in patients with hepatitis C virus infection. Gastroenterology 2010;138:447-62.
-
(2010)
Gastroenterology
, vol.138
, pp. 447-462
-
-
Sarrazin, C.1
Zeuzem, S.2
-
33
-
-
79958830099
-
Hepatitis C virus resistance to protease inhibitors
-
Halfon P, Locarnini S. Hepatitis C virus resistance to protease inhibitors. J Hepatol 2011;55:192-206
-
(2011)
J Hepatol
, vol.55
, pp. 192-206
-
-
Halfon, P.1
Locarnini, S.2
-
34
-
-
77950203857
-
Viral resistance to specifically targeted antiviral therapies for hepatitis C (STAT-Cs)
-
Kieffer T, Kwong A, Picchio G. Viral resistance to specifically targeted antiviral therapies for hepatitis C (STAT-Cs). J Antimicrob Chemother 2010;65:202-12
-
(2010)
J Antimicrob Chemother
, vol.65
, pp. 202-212
-
-
Kieffer, T.1
Kwong, A.2
Picchio, G.3
-
35
-
-
78649644443
-
Susceptibility of treatment-naive HCV clinical isolates to HCV protease inhibitors
-
Bae A, Sun S, Qi X, et al. Susceptibility of treatment-naive HCV clinical isolates to HCV protease inhibitors. Antimicrob Agents Chemother 2010;54:5288-97
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 5288-5297
-
-
Bae, A.1
Sun, S.2
Qi, X.3
-
36
-
-
20944447120
-
Replication fitness and NS5B drug sensitivity of diverse hepatitis C virus isolates characterized by using a transient replication assay
-
DOI 10.1128/AAC.49.5.2059-2069.2005
-
Ludmerer S, Graham D, Boots E, et al. Replication fitness and NS5B drug sensitivity of diverse hepatitis C virus isolates characterized by using a transient replication assay. Antimicrob Agents Chemother 2005;49:2059-69 (Pubitemid 40631625)
-
(2005)
Antimicrobial Agents and Chemotherapy
, vol.49
, Issue.5
, pp. 2059-2069
-
-
Ludmerer, S.W.1
Graham, D.J.2
Boots, E.3
Murray, E.M.4
Simcoe, A.5
Markel, E.J.6
Grobler, J.A.7
Flores, O.A.8
Olsen, D.B.9
Hazuda, D.J.10
Lafemina, R.L.11
-
37
-
-
66149128046
-
GT-1a or GT-1b subtype-specific resistance profiles for hepatitis C virus inhibitors telaprevir and HCV-796
-
McCown M, Rajyaguru S, Kular S, et al. GT-1a or GT-1b subtype-specific resistance profiles for hepatitis C virus inhibitors telaprevir and HCV-796. Antimicrob Agents Chemother 2009;53:2129-32
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 2129-2132
-
-
McCown, M.1
Rajyaguru, S.2
Kular, S.3
-
38
-
-
58749089998
-
New therapies for hepatitis C virus infection
-
Soriano V, Peters M, Zeuzem S. New therapies for hepatitis C virus infection. Clin Infect Dis 2009;48:313-20
-
(2009)
Clin Infect Dis
, vol.48
, pp. 313-320
-
-
Soriano, V.1
Peters, M.2
Zeuzem, S.3
-
39
-
-
51749123143
-
Natural prevalence of HCV variants with decreased sensitivity to NS3-4A protease inhibitors in treatment-naive subjects
-
Bartels D, Zhou Y, Zhang E, et al. Natural prevalence of HCV variants with decreased sensitivity to NS3-4A protease inhibitors in treatment-naive subjects. J Infect Dis 2008;198:800-7
-
(2008)
J Infect Dis
, vol.198
, pp. 800-807
-
-
Bartels, D.1
Zhou, Y.2
Zhang, E.3
-
40
-
-
58149388300
-
Naturally occurring dominant resistance mutations to HCV protease and polymerase inhibitors in treatment-naive patients
-
Kuntzen T, Timm J, Berical A, et al. Naturally occurring dominant resistance mutations to HCV protease and polymerase inhibitors in treatment-naive patients. Hepatology 2008;48:1769-78
-
(2008)
Hepatology
, vol.48
, pp. 1769-1778
-
-
Kuntzen, T.1
Timm, J.2
Berical, A.3
-
41
-
-
65449157987
-
Hepatitis C virus drug resistance and immune-driven adaptations: Relevance to new antiviral therapy
-
Gaudieri S, Rauch A, Pfafferott K, et al. Hepatitis C virus drug resistance and immune-driven adaptations: relevance to new antiviral therapy. Hepatology 2009;49:1069-82
-
(2009)
Hepatology
, vol.49
, pp. 1069-1082
-
-
Gaudieri, S.1
Rauch, A.2
Pfafferott, K.3
-
42
-
-
79960468479
-
Natural variation in drug susceptibility to HCV polymerase inhibitors in treatment-naive HCV patient isolates
-
Sun S, Bae A, Qi X, et al. Natural variation in drug susceptibility to HCV polymerase inhibitors in treatment-naive HCV patient isolates. J Viral Hepat 2011;18:861-70
-
(2011)
J Viral Hepat
, vol.18
, pp. 861-870
-
-
Sun, S.1
Bae, A.2
Qi, X.3
-
43
-
-
80051599715
-
HCV protease variability and anti-HCV protease inhibitor resistance in HIV/HCV-coinfected patients
-
Trimoulet P, Belzunce C, Faure M, et al. HCV protease variability and anti-HCV protease inhibitor resistance in HIV/HCV-coinfected patients. HIV Med 2011;12:506-9
-
(2011)
HIV Med
, vol.12
, pp. 506-509
-
-
Trimoulet, P.1
Belzunce, C.2
Faure, M.3
-
44
-
-
81855199759
-
Impact of antiretroviral therapy on the variability of the HCV NS5B polymerase in HIV/HCV co-infected patients
-
Plaza Z, Soriano V, Gonzalez MM, et al. Impact of antiretroviral therapy on the variability of the HCV NS5B polymerase in HIV/HCV co-infected patients. J Antimicrob Chemother 2011;66:2838-42
-
(2011)
J Antimicrob Chemother
, vol.66
, pp. 2838-2842
-
-
Plaza, Z.1
Soriano, V.2
Gonzalez, M.M.3
-
45
-
-
77952035218
-
Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect
-
Gao M, Nettles R, Belema M, et al. Chemical genetics strategy identifies an HCV NS5A inhibitor with a potent clinical effect. Nature 2010;465:96-100
-
(2010)
Nature
, vol.465
, pp. 96-100
-
-
Gao, M.1
Nettles, R.2
Belema, M.3
-
46
-
-
79952296871
-
Recombinant HCV variants with NS5A from genotypes 1-7 have different sensitivities to an NS5A inhibitor but not interferon-alpha
-
Scheel T, Gottwein J, Mikkelsen L, et al. Recombinant HCV variants with NS5A from genotypes 1-7 have different sensitivities to an NS5A inhibitor but not interferon-alpha. Gastroenterology 2011;140:1032-42
-
(2011)
Gastroenterology
, vol.140
, pp. 1032-1042
-
-
Scheel, T.1
Gottwein, J.2
Mikkelsen, L.3
-
47
-
-
79960451927
-
Characterization of virologic escape in HCV genotype 1 null responders receiving a combination of the NS3 protease inhibitor BMS-650032 and NS5A inhibitor BMS-790052
-
Abstracts of the 46th EASL Annual Meeting, Berlin, Germany, 2011. Abstract 63
-
McPhee F, Hernandez D, Yu F, et al. Characterization of virologic escape in HCV genotype 1 null responders receiving a combination of the NS3 protease inhibitor BMS-650032 and NS5A inhibitor BMS-790052. In: Abstracts of the 46th EASL Annual Meeting, Berlin, Germany, 2011. Abstract. 63. J Hepatol 2011;54(Suppl 1): 28-9
-
(2011)
J Hepatol
, vol.54
, Issue.SUPPL. 1
, pp. 28-29
-
-
McPhee, F.1
Hernandez, D.2
Yu, F.3
-
48
-
-
84858415895
-
Prevalence of natural polymorphisms at the Hepatitis C virus NS5A gene associated with resistance to BMS-052, a NS5A inhibitor
-
press
-
Plaza Z, Soriano V, Vispo E, et al. Prevalence of natural polymorphisms at the Hepatitis C virus NS5A gene associated with resistance to BMS-052, a NS5A inhibitor. Antivir Ther 2012; In press
-
(2012)
Antivir Ther
-
-
Plaza, Z.1
Soriano, V.2
Vispo, E.3
-
49
-
-
79953224799
-
Potency, safety and pharmacokinetics of the NS3/4A protease inhibitor BI201335 in patients with chronic HCV genotype 1 infection
-
Manns M, Bourliere M, Benhamou Y, et al. Potency, safety and pharmacokinetics of the NS3/4A protease inhibitor BI201335 in patients with chronic HCV genotype 1 infection. J Hepatol 2011;54:1114-22
-
(2011)
J Hepatol
, vol.54
, pp. 1114-1122
-
-
Manns, M.1
Bourliere, M.2
Benhamou, Y.3
-
50
-
-
78049527728
-
Oral combination therapy with a nucleoside polymerase inhibitor (RG1728) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): A randomized, double-blind, placebo-controlled, dose-escalation trial
-
Gane E, Roberts S, Stedman C, et al. Oral combination therapy with a nucleoside polymerase inhibitor (RG1728) and danoprevir for chronic hepatitis C genotype 1 infection (INFORM-1): a randomized, double-blind, placebo-controlled, dose-escalation trial. Lancet 2010;376:1467-75
-
(2010)
Lancet
, vol.376
, pp. 1467-1475
-
-
Gane, E.1
Roberts, S.2
Stedman, C.3
-
51
-
-
84856293564
-
Virologic response to an interferon-free regimen of BI201335 and BI207127, with and without ribavirin, in treatment-naive patients with chronic genotype-1 HCV infection: Week 12 interim results of the SOUND-C2 study
-
LB-15
-
Zeuzem S, Soriano V, Asselah T, et al. Virologic response to an interferon-free regimen of BI201335 and BI207127, with and without ribavirin, in treatment-naive patients with chronic genotype-1 HCV infection: Week 12 interim results of the SOUND-C2 study. Hepatology 2011;54(Suppl): 1436 [LB-15
-
(2011)
Hepatology
, vol.54
, Issue.SUPPL.
, pp. 1436
-
-
Zeuzem, S.1
Soriano, V.2
Asselah, T.3
-
52
-
-
79960451927
-
Characterization of virologic escape in HCV genotype 1 null responders receiving a combination of the NS3 protease inhibitor BMS-650032 and NS5A inhibitor 790052
-
McPhee F, Hernandez D, Yu F, et al. characterization of virologic escape in HCV genotype 1 null responders receiving a combination of the NS3 protease inhibitor BMS-650032 and NS5A inhibitor 790052. J Hepatol 2011;54(Suppl 1):28-9
-
(2011)
J Hepatol
, vol.54
, Issue.SUPPL. 1
, pp. 28-29
-
-
McPhee, F.1
Hernandez, D.2
Yu, F.3
-
53
-
-
79960471175
-
Once daily dual nucleotide combination of PSI-938 and PSI-7977 provides 94% HCV-RNA < LOD at day 14: First purine/pyrimidine clinical combination data (the NUCLEAR study)
-
Abstracts of the 46th EASL Annual Meeting, Berlin, Germany, 2011 [abstract 1370]
-
Lawitz E, Rodriguez-Torres M, Denning J, et al. Once daily dual nucleotide combination of PSI-938 and PSI-7977 provides 94% HCV-RNA < LOD at day 14: first purine/pyrimidine clinical combination data (the NUCLEAR study). In: Abstracts of the 46th EASL Annual Meeting, Berlin, Germany, 2011 [abstract 1370]. J Hepatol 2011;54(Suppl 1):543
-
(2011)
J Hepatol
, vol.54
, Issue.SUPPL. 1
, pp. 543
-
-
Lawitz, E.1
Rodriguez-Torres, M.2
Denning, J.3
-
54
-
-
84856252952
-
Hepatitis C treatment -clearing the mind
-
press
-
Forton D. Hepatitis C treatment -clearing the mind. J Hepatol 2012; In press
-
(2012)
J Hepatol
-
-
Forton, D.1
|