A systematic method development strategy for quantitative color measurement in drug substances, starting materials, and synthetic intermediates

Journal of Pharmaceutical Innovation

Volumn 6, Issue 4, 2011, Pages 217-231

  Zhou, Leon ^a   Vogt, Frederick G ^a   Overstreet, Patricia Ann ^a   Dougherty, John T ^a   Clawson, Jacalyn S ^a   Kord, Alireza S ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Appearance testing; Diffuse reflectance spectroscopy; Method development strategy (MDS); Quality by design (QbD); Quantitative color measurement; Transmittance spectroscopy

Indexed keywords

2,3 DIMETHYL INDAZOL 6 AMINE; INDAZOLE DERIVATIVE; PAZOPANIB; PIROXICAM; UNCLASSIFIED DRUG;

ARTICLE; COLOR; CONTROL STRATEGY; DIFFUSE REFLECTANCE SPECTROSCOPY; DRUG INDUSTRY; DRUG SYNTHESIS; INTERMETHOD COMPARISON; METHOD DEVELOPMENT STRATEGY; METHODOLOGY; PERFORMANCE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; QUANTITATIVE COLOR MEASUREMENT; RISK ASSESSMENT; SOLID STATE; SOLID STATE DIFFUSE REFLECTANCE SPECTROSCOPY; SOLUTION STATE TRANSMITTANCE SPECTROSCOPY; SPECTROSCOPY; VALIDATION PROCESS;

EID: 84856300369     PISSN: 18725120     EISSN: 19398042     Source Type: Journal    
DOI: 10.1007/s12247-011-9115-5     Document Type: Article

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