Effects of bone morphogenetic proteins on primary human renal cells and the generation of bone morphogenetic protein-7-expressing cells for application in bioartificial kidneys

Tissue Engineering - Part A

Volumn 18, Issue 3-4, 2012, Pages 262-276

  Tasnim, Farah ^a   Kandasamy, Karthikeyan ^a   Muck, Joscha S ^a   Ibrahim, Mohammed Shahrudin Bin ^a   Ying, Jackie Y ^a   Zink, Daniele ^a  

^a INSTITUTE OF BIOENGINEERING AND NANOTECHNOLOGY   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; PEPTIDES; PURIFICATION;

BIOARTIFICIAL; BONE MORPHOGENETIC PROTEINS; CELL PERFORMANCE; CLINICAL TRIAL; CONCENTRATION-DEPENDENT; FUNCTIONAL PERFORMANCE; GROWTH FACTOR; IN-VITRO; OPTIMAL CONCENTRATION; RENAL CELL; SUBSTRATE SURFACE; THERAPEUTIC APPLICATION; TRANSDIFFERENTIATION;

CELLS;

ACTIN; ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; GAMMA GLUTAMYLTRANSFERASE; OSTEOGENIC PROTEIN 1; RECOMBINANT BONE MORPHOGENETIC PROTEIN 2; RECOMBINANT HUMAN BONE MORPHOGENETIC PROTEIN-2; RECOMBINANT PROTEIN; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL; ANTIBODY SPECIFICITY; ARTICLE; ARTIFICIAL KIDNEY; BIOREACTOR; BONE DEVELOPMENT; CELL CULTURE; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; EPITHELIUM; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; GENETICS; HUMAN; KIDNEY PROXIMAL TUBULE; METABOLISM; METHODOLOGY; MOUSE; PHOSPHORYLATION; SECRETION; TISSUE ENGINEERING;

ACTINS; ALKALINE PHOSPHATASE; ANIMALS; BIOREACTORS; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 7; CELLS, CULTURED; EPITHELIUM; GAMMA-GLUTAMYLTRANSFERASE; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; HUMANS; KIDNEY TUBULES, PROXIMAL; KIDNEY, ARTIFICIAL; MICE; ORGAN SPECIFICITY; OSTEOGENESIS; PHOSPHORYLATION; RECOMBINANT PROTEINS; SMAD PROTEINS; TISSUE ENGINEERING; TRANSFORMING GROWTH FACTOR BETA;

EID: 84856279685     PISSN: 19373341     EISSN: 1937335X     Source Type: Journal    
DOI: 10.1089/ten.tea.2011.0149     Document Type: Article

References (4)

1. Ni, M., Teo, J.C.M., bin Ibrahim, M.S., Zhang, K., Tasnim, F., Chow, P.-Y., Zink, D., and Ying, J.Y. Characterization of membrane materials and membrane coatings for bioreactor units of bioartificial kidneys. Biomaterials 32, 1465, 2011.
2. Meister, A., Tate, S.S., and Griffith, O.W. Gamma-glutamyl transpeptidase. Methods Enzymol 77, 237, 1981.
3. Wieser, M., Stadler, G., Jennings, P., Streubel, B., Pfaller, W., Ambros, P., Riedl, C., Katinger, H., Grillari, J., and Grillari-Voglauer, R. hTERT alone immortalizes epithelial cells of renal proximal tubules without changing their functional characteristics. Am J Physiol Renal Physiol 295, F1365, 2008.
4. Asahina, I., Sampath, T.K., Nishimura, I., and Hauschka, P.V. Human osteogenic protein-1 induces both chondroblastic and osteoblastic differentiation of osteoprogenitor cells derived from newborn rat calvaria. J Cell Biol 123, 921, 1993.