A functional variant in promoter region of platelet-derived growth factor-D is probably associated with intracerebral hemorrhage

Journal of Neuroinflammation

Volumn 9, Issue , 2012, Pages

  Bai, Yongyi ^a,b   Chen, Jingzhou ^a   Sun, Kai ^a   Wang, Yibo ^a   Hui, Rutai ^a  

^a FUWAI HOSPITAL   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Genetics; Intracerebral hemorrhage; Platelet derived growth factor D; Risk factors

Indexed keywords

PLATELET DERIVED GROWTH FACTOR D; LYMPHOKINE; PDGFD PROTEIN, HUMAN; PLATELET DERIVED GROWTH FACTOR;

ADULT; ARTICLE; BRAIN HEMORRHAGE; CONTROLLED STUDY; FEMALE; FOLLOW UP; GENETIC ASSOCIATION; GENETIC RISK; GENETIC VARIABILITY; HIGH RISK PATIENT; HUMAN; LACUNAR STROKE; MAJOR CLINICAL STUDY; MALE; NEUROPATHOLOGY; OCCLUSIVE CEREBROVASCULAR DISEASE; PROMOTER REGION; RECURRENT DISEASE; RISK ASSESSMENT; RISK REDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; WILD TYPE; AGED; ASIAN; CLINICAL TRIAL; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; MIDDLE AGED; MULTICENTER STUDY; NONPARAMETRIC TEST; STATISTICAL MODEL; STROKE;

AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CEREBRAL HEMORRHAGE; FEMALE; FOLLOW-UP STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LOGISTIC MODELS; LYMPHOKINES; MALE; MIDDLE AGED; PLATELET-DERIVED GROWTH FACTOR; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS, GENETIC; STATISTICS, NONPARAMETRIC; STROKE; STROKE, LACUNAR;

EID: 84856272124     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-9-26     Document Type: Article

References (22)

1. Liu M, Wu B, Wang WZ, Lee LM, Zhang SH, Kong LZ. Stroke in China: epidemiology, prevention, and management strategies. Lancet Neurol 2007, 6:456-464. 10.1016/S1474-4422(07)70004-2, 17434100.
2. Tunstall-Pedoe H, Kuulasmaa K, Amouyel P, Arveiler D, Rajakangas AM, Pajak A. Myocardial infarction and coronary deaths in the World Health Organization MONICA Project. Registration procedures, event rates, and case-fatality rates in 38 populations from 21 countries in four continents. Circulation 1994, 90:583-612.
3. Reed DM. The paradox of high risk of stroke in populations with low risk of coronary heart disease. Am J Epidemiol 1990, 131:579-588.
4. Bai Y, Chen J, Sun K, Xin Y, Liu J, Hui R. Common genetic variation in DDAH2 is associated with intracerebral haemorrhage in a Chinese population: a multi-centre case-control study in China. Clin Sci (Lond) 2009, 117:273-279.
5. Shi FL, Hart RG, Sherman DG, Tegeler CH. Stroke in the People's Republic of China. Stroke 1989, 20:1581-1585. 10.1161/01.STR.20.11.1581, 2683247.
6. He J, Klag MJ, Wu Z, Whelton PK. Stroke in the People's Republic of China.I. Geographic variations in incidence and risk factors. Stroke 1995, 26:2222-2227. 10.1161/01.STR.26.12.2222, 7491640.
7. Lloyd-Jones D, Adams R, Carnethon M, De Simone G, Ferguson TB, Flegal K, Ford E, Furie K, Go A, Greenlund K, Haase N, Hailpern S, Ho M, Howard V, Kissela B, Kittner S, Lackland D, Lisabeth L, Marelli A, McDermott M, Meigs J, Mozaffarian D, Nichol G, O'Donnell C, Roger V, Rosamond W, Sacco R, Sorlie P, Stafford R, Steinberger J, et al. Heart disease and stroke statistics--2009 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Circulation 2009, 119:480-486.
8. Yang QD, Niu Q, Zhou YH, Liu YH, Xu HW, Gu WP, Tian FF, Xie YQ, Zhang L, Xia J. Incidence of cerebral hemorrhage in the Changsha community. A prospective study from 1986 to 2000. Cerebrovasc Dis 2004, 17:303-313. 10.1159/000077341, 15026613.
9. Woo D, Sauerbeck LR, Kissela BM, Khoury JC, Szaflarski JP, Gebel J, Shukla R, Pancioli AM, Jauch EC, Menon AG, Deka R, Carrozzella JA, Moomaw CJ, Fontaine RN, Broderick JP. Genetic and environmental risk factors for intracerebral hemorrhage: preliminary results of a population-based study. Stroke 2002, 33:1190-1195. 10.1161/01.STR.0000014774.88027.22, 11988589.
10. Li Z, Sun L, Zhang H, Liao Y, Wang D, Zhao B, Zhu Z, Zhao J, Ma A, Han Y, Wang Y, Shi Y, Ye J, Hui R. Elevated plasma homocysteine was associated with hemorrhagic and ischemic stroke, but methylenetetrahydrofolate reductase gene C677T polymorphism was a risk factor for thrombotic stroke: a Multicenter Case-Control Study in China. Stroke 2003, 34:2085-2090. 10.1161/01.STR.0000086753.00555.0D, 12907815.
11. Rost NS, Greenberg SM, Rosand J. The genetic architecture of intracerebral hemorrhage. Stroke 2008, 39:2166-2173. 10.1161/STROKEAHA.107.501650, 18467649.
12. LaRochelle WJ, Jeffers M, McDonald WF, Chillakuru RA, Giese NA, Lokker NA, Sullivan C, Boldog FL, Yang M, Vernet C, Burgess CE, Fernandes E, Deegler LL, Rittman B, Shimkets J, Shimkets RA, Rothberg JM, Lichenstein HS. PDGF-D, a new protease-activated growth factor. Nat Cell Biol 2001, 3:517-521. 10.1038/35074593, 11331882.
13. Wagsater D, Zhu C, Bjorck HM, Eriksson P. Effects of PDGF-C and PDGF-D on monocyte migration and MMP-2 and MMP-9 expression. Atherosclerosis 2009, 202:415-423. 10.1016/j.atherosclerosis.2008.04.050, 18573494.
14. Li R, Maminishkis A, Wang FE, Miller SS. PDGF-C and -D induced proliferation/migration of human RPE is abolished by inflammatory cytokines. Invest Ophthalmol Vis Sci 2007, 48:5722-5732. 10.1167/iovs.07-0327, 18055825.
15. Uutela M, Wirzenius M, Paavonen K, Rajantie I, He Y, Karpanen T, Lohela M, Wiig H, Salven P, Pajusola K, Eriksson U, Alitalo K. PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis. Blood 2004, 104:3198-3204. 10.1182/blood-2004-04-1485, 15271796.
16. Sun L, Li Z, Zhang H, Ma A, Liao Y, Wang D, Zhao B, Zhu Z, Zhao J, Zhang Z, Wang W, Hui R. Pentanucleotide TTTTA repeat polymorphism of apolipoprotein(a) gene and plasma lipoprotein(a) are associated with ischemic and hemorrhagic stroke in Chinese: a multicenter case-control study in China. Stroke 2003, 34:1617-1622. 10.1161/01.STR.0000078370.12085.02, 12791946.
17. Liu MY, Eyries M, Zhang C, Santiago FS, Khachigian LM. Inducible platelet-derived growth factor D-chain expression by angiotensin II and hydrogen peroxide involves transcriptional regulation by Ets-1 and Sp1. Blood 2006, 107:2322-2329. 10.1182/blood-2005-06-2377, 16189269.
18. Han SH, Liu JP, Tan A, Peng J, Zhang RL, Gao ST, Huang DN, Yu L, Wang CJ, Cheng JQ, Nie SF. Association of platelet-derived growth factor-D gene polymorphism with ischemic stroke in a Chinese case-control study. Blood Coagul Fibrinolysis 2008, 19:415-419. 10.1097/MBC.0b013e3283049650, 18600092.
19. Chen J, Han Y, Lin C, Zhen Y, Song X, Teng S, Chen C, Chen Y, Zhang Y, Hui R. PDGF-D contributes to neointimal hyperplasia in rat model of vessel injury. Biochem Biophys Res Commun 2005, 329:976-983. 10.1016/j.bbrc.2005.02.062, 15752751.
20. Uutela M, Lauren J, Bergsten E, Li X, Horelli-Kuitunen N, Eriksson U, Alitalo K. Chromosomal location, exon structure, and vascular expression patterns of the human PDGFC and PDGFD genes. Circulation 2001, 103:2242-2247.
21. Kalluri R. Basement membranes: structure, assembly and role in tumour angiogenesis. Nat Rev Cancer 2003, 3:422-433. 10.1038/nrc1094, 12778132.
22. Hua Y, Keep RF, Gu Y, Xi G. Thrombin and brain recovery after intracerebral hemorrhage. Stroke 2009, 40:S88-89. 10.1161/STROKEAHA.108.533281, 2649979, 19064789.