Tetrahydrobiopterin and endothelial nitric oxide synthase uncoupling

Hypertension

Volumn 59, Issue 2, 2012, Pages

  Tsikas, Dimitrios ^a   Bohmer, Anke ^a   Flentje, Markus ^a  

^a HANNOVER MEDICAL SCHOOL   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FOLIC ACID; NITRIC OXIDE; OXYGEN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUPEROXIDE; TETRAHYDROBIOPTERIN; XANTHINE OXIDASE;

ABDOMINAL AORTA ANEURYSM; BIOAVAILABILITY; BIOSYNTHESIS; BLOOD PRESSURE; CHEMICAL REACTION; CONCENTRATION RESPONSE; ENDOTHELIAL DYSFUNCTION; ENZYME ACTIVITY; LETTER; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN FUNCTION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SCAVENGING SYSTEM; SUPPLEMENTATION;

ANIMALS; AORTIC ANEURYSM, ABDOMINAL; FOLIC ACID; GTP CYCLOHYDROLASE; NITRIC OXIDE SYNTHASE TYPE III;

EID: 84856265397     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.111.188359     Document Type: Letter

References (4)

1. Gao L, Siu KL, Chalipsky K, Nguyen A, Chen P, Weintraub NL, Galis Z, Cai H. Role of uncoupled endothelial nitric oxide synthase in abdominal aortic aneurysm formation: treatment with folic acid. Hypertension. 2012;59:158-166.
2. Vasquez-Vivar J, Kalyanaraman B, Martasek P, Hogg N, Masters BS, Karoui H, Tordo P, Pritchard KA Jr. Superoxide generation by endothelial nitric oxide synthase: the influence of cofactors. Proc Natl Acad Sci U S A. 1998;95:9220-9225. (Pubitemid 28506212)
3. Fliser D, Wagner KK, Loos A, Tsikas D, Haller H. Chronic angiotensin II receptor blockade reduces (intra) renal vascular resistance in patients with type 2 diabetes. J Am Soc Nephrol. 2005;16:1135-1140. (Pubitemid 41710325)
4. Tsikas D, Sandmann J, Savva A, Luessen P, Böger RH, Gutzki FM, Mayer B, Frölich JC. Assessment of nitric oxide synthase activity in vitro and in vivo by gas chromatography-mass spectrometry. J Chromatogr B. 2000;742:143-153. (Pubitemid 30330932)