-
1
-
-
0019952276
-
Proposals for the classification of the myelodysplastic syndromes
-
Bennett JM, Catovsky D, Daniel MT et al (1982) Proposals for the classification of the myelodysplastic syndromes. Br J Haematol 51:189-199 (Pubitemid 12073508)
-
(1982)
British Journal of Haematology
, vol.51
, Issue.2
, pp. 189-199
-
-
Bennett, J.M.1
Catovsky, D.2
Daniel, M.T.3
-
2
-
-
21244467166
-
Epigenetic and chromatin modifiers as targeted therapy of hematologic malignancies
-
DOI 10.1200/JCO.2005.16.600
-
Bhalla KN (2005) Epigenetic and chromatin modifiers as targeted therapy of hematologic malignancies. J Clin Oncol 23:3971-3993 (Pubitemid 46218700)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.17
, pp. 3971-3993
-
-
Bhalla, K.N.1
-
3
-
-
77955981797
-
FISH analysis of circulating CD34+ cells as a new tool for genetic monitoring in MDS: Verification of the method and application to 27 MDS patients
-
Braulke F, Schanz J, Jung K et al (2010) FISH analysis of circulating CD34+ cells as a new tool for genetic monitoring in MDS: verification of the method and application to 27 MDS patients. Leuk Res 34:1296-1301
-
(2010)
Leuk Res
, vol.34
, pp. 1296-1301
-
-
Braulke, F.1
Schanz, J.2
Jung, K.3
-
4
-
-
33745968917
-
Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia
-
DOI 10.1182/blood-2005-10-4149
-
Cheson BD, Greenberg PL, Bennett JM et al (2006) Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. Blood 108:419-425 (Pubitemid 44061337)
-
(2006)
Blood
, vol.108
, Issue.2
, pp. 419-425
-
-
Cheson, B.D.1
Greenberg, P.L.2
Bennett, J.M.3
Lowenberg, B.4
Wijermans, P.W.5
Nimer, S.D.6
Pinto, A.7
Beran, M.8
De Witte, T.M.9
Stone, R.M.10
Mittelman, M.11
Sanz, G.F.12
Gore, S.D.13
Schiffer, C.A.14
Kantarjian, H.15
-
5
-
-
34547645788
-
Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition
-
DOI 10.1111/j.1365-2141.2007.06707.x
-
Choi SH, Byun HM, Kwan JM, Issa JP, Yang AS (2007) Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition. Br J Haematol 138:616-623 (Pubitemid 47206723)
-
(2007)
British Journal of Haematology
, vol.138
, Issue.5
, pp. 616-623
-
-
Choi, S.H.1
Byun, H.-M.2
Kwan, J.M.3
Issa, J.-P.J.4
Yang, A.S.5
-
6
-
-
68049117856
-
5' Azacitidine in combination with valproic acid induces complete remissions in patients with advanced acute myeloid leukaemia but does not eradicate clonal leukaemic stem/progenitor cells
-
Craddock C, Goardon N, Griffiths M, Cavenagh JD, Siddique S, Vyas P (2008) 5' Azacitidine in Combination with Valproic Acid Induces Complete Remissions in Patients with Advanced Acute Myeloid Leukaemia but Does Not Eradicate Clonal Leukaemic Stem/Progenitor Cells. ASH Annual Meeting Abstracts 112:945
-
(2008)
ASH Annual Meeting Abstracts
, vol.112
, pp. 945
-
-
Craddock, C.1
Goardon, N.2
Griffiths, M.3
Cavenagh, J.D.4
Siddique, S.5
Vyas, P.6
-
7
-
-
62849104641
-
Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: A randomised, open-label, phase III study
-
Fenaux P, Mufti GJ, Hellstrom-Lindberg E et al (2009) Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study. Lancet Oncol 10:223-232
-
(2009)
Lancet Oncol
, vol.10
, pp. 223-232
-
-
Fenaux, P.1
Mufti, G.J.2
Hellstrom-Lindberg, E.3
-
8
-
-
77449149373
-
Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia
-
Fenaux P, Mufti GJ, Hellström-Lindberg E et al (2010) Azacitidine prolongs overall survival compared with conventional care regimens in elderly patients with low bone marrow blast count acute myeloid leukemia. J Clin Oncol 28:562-569
-
(2010)
J Clin Oncol
, vol.28
, pp. 562-569
-
-
Fenaux, P.1
Mufti, G.J.2
Hellström-Lindberg, E.3
-
9
-
-
18244383806
-
Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells
-
DOI 10.1093/emboj/20.24.6969
-
Göttlicher M, Minucci S, Zhu P et al (2001) Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. EMBO J 20:6969-6978 (Pubitemid 34062289)
-
(2001)
EMBO Journal
, vol.20
, Issue.24
, pp. 6969-6978
-
-
Gottlicher, M.1
Minucci, S.2
Zhu, P.3
Kramer, O.H.4
Schimpf, A.5
Giavara, S.6
Sleeman, J.P.7
Lo Coco, F.8
Nervi, C.9
Pelicci, P.G.10
Heinzel, T.11
-
10
-
-
0030897009
-
International scoring system for evaluating prognosis in myelodysplastic syndromes
-
Greenberg P, Cox C, LeBeau MM et al (1997) International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 89:2079-2088 (Pubitemid 27132124)
-
(1997)
Blood
, vol.89
, Issue.6
, pp. 2079-2088
-
-
Greenberg, P.1
Cox, C.2
LeBeau, M.M.3
Fenaux, P.4
Morel, P.5
Sanz, G.6
Sanz, M.7
Vallespi, T.8
Hamblin, T.9
Oscier, D.10
Ohyashiki, K.11
Toyama, K.12
Aul, C.13
Mufti, G.14
Bennett, J.15
-
11
-
-
0032188805
-
The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial
-
Grimwade D, Walker H, Oliver F et al (1998) The importance of diagnostic cytogenetics on outcome in AML: analysis of 1, 612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. Blood 92:2322-2333 (Pubitemid 28452973)
-
(1998)
Blood
, vol.92
, Issue.7
, pp. 2322-2333
-
-
Grimwade, D.1
Walker, H.2
Oliver, F.3
Wheatley, K.4
Harrison, C.5
Harrison, G.6
Rees, J.7
Hann, I.8
Stevens, R.9
Burnett, A.10
Goldstone, A.11
-
12
-
-
0033395790
-
The World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues. Report of the Clinical Advisory Committee Meeting, Airlie House, Virginia, November, 1997
-
DOI 10.1023/A:1008375931236
-
Harris NL, Jaffe ES, Diebold J et al (1999) The World Health Organization classification of neoplastic diseases of the hematopoietic and lymphoid tissues. Report of the Clinical Advisory Committee meeting, Airlie House, Virginia, November, 1997. Ann Oncol 10:1419-1432 (Pubitemid 30017051)
-
(1999)
Annals of Oncology
, vol.10
, Issue.12
, pp. 1419-1432
-
-
Harris, N.L.1
Jaffe, E.S.2
Diebold, J.3
Flandrin, G.4
Muller-Hermelink, H.K.5
Vardiman, J.6
Lister, T.A.7
Bloomfield, C.D.8
-
13
-
-
66749108988
-
Randomized phase II study of combined epigenetic therapy: Decitabine vs. decitabine and valproic acid in MDS and AML
-
Issa JP, Castoro R, Ravandi-Kashani F et al (2008) Randomized phase II study of combined epigenetic therapy: decitabine vs. decitabine and valproic acid in MDS and AML. ASH Annual Meeting Abstracts 112:228
-
(2008)
ASH Annual Meeting Abstracts
, vol.112
, pp. 228
-
-
Issa, J.P.1
Castoro, R.2
Ravandi-Kashani, F.3
-
14
-
-
77953234036
-
Azacytidine in refractory or relapsed AML after intensive chemotherapy (IC): Results of the French ATU Program
-
Itzykson R, Thepot S, Recher C et al (2009) Azacytidine in refractory or relapsed AML after intensive chemotherapy (IC): results of the French ATU Program. ASH Annual Meeting Abstracts 114:1054
-
(2009)
ASH Annual Meeting Abstracts
, vol.114
, pp. 1054
-
-
Itzykson, R.1
Thepot, S.2
Recher, C.3
-
15
-
-
4444309863
-
Treatment of myelodysplastic syndromes with valproic acid alone or in combination with all-trans retinoic acid
-
DOI 10.1182/blood-2003-12-4333
-
Kuendgen A, Strupp C, Aivado M et al (2004) Treatment of myelodysplastic syndromes with valproic acid alone or in combination with all-trans retinoic acid. Blood 104:1266-1269 (Pubitemid 39166498)
-
(2004)
Blood
, vol.104
, Issue.5
, pp. 1266-1269
-
-
Kuendgen, A.1
Strupp, C.2
Aivado, M.3
Bernhardt, A.4
Hildebrandt, B.5
Haas, R.6
Germing, U.7
Gattermann, N.8
-
16
-
-
29744454120
-
The histone deacetylase (HDAC) inhibitor valproic acid as monotherapy or in combination with all-trans retinoic acid in patients with acute myeloid leukemia
-
DOI 10.1002/cncr.21552
-
Kuendgen A, Schmid M, Schlenk R et al (2006) The histone deacetylase (HDAC) inhibitor valproic acid as monotherapy or in combination with all-trans retinoic acid in patients with acute myeloid leukemia. Cancer 106:112-119 (Pubitemid 43032555)
-
(2006)
Cancer
, vol.106
, Issue.1
, pp. 112-119
-
-
Kuendgen, A.1
Schmid, M.2
Schlenk, R.3
Knipp, S.4
Hildebrandt, B.5
Steidl, C.6
Germing, U.7
Haas, R.8
Dohner, H.9
Gattermann, N.10
-
17
-
-
34548176264
-
Valproic acid for the treatment of myeloid malignancies
-
DOI 10.1002/cncr.22891
-
Kuendgen A, Gattermann N (2007) Valproic acid for the treatment of myeloid malignancies. Cancer 110:943-954 (Pubitemid 47312858)
-
(2007)
Cancer
, vol.110
, Issue.5
, pp. 943-954
-
-
Kuendgen, A.1
Gattermann, N.2
-
18
-
-
71649091538
-
Continued treatment with an outpatient maintenance schedule of decitabine in older AML patients ineligible for induction chemotherapy: Results of the 00331 phase II multicenter trial
-
Lubbert M, Schmid M, Ruter B et al (2008) Continued treatment with an outpatient maintenance schedule of decitabine in older AML patients ineligible for induction chemotherapy: results of the 00331 phase II multicenter trial. ASH Annual Meeting Abstracts 112:2965
-
(2008)
ASH Annual Meeting Abstracts
, vol.112
, pp. 2965
-
-
Lubbert, M.1
Schmid, M.2
Ruter, B.3
-
19
-
-
77953458163
-
5-Azacytidine for the treatment of acute myeloid leukemia: A retrospective, multicenter study of 55 patients
-
Maurillo L, Spagnoli A, Genuardi M et al (2008) 5-Azacytidine for the treatment of acute myeloid leukemia: a retrospective, multicenter study of 55 patients. ASH Annual Meeting Abstracts 112:1947
-
(2008)
ASH Annual Meeting Abstracts
, vol.112
, pp. 1947
-
-
Maurillo, L.1
Spagnoli, A.2
Genuardi, M.3
-
20
-
-
78649299120
-
Influence of karyotype on overall survival in patients with higher-risk myelodysplastic syndrome treated with azacitidine or a conventional care regimen
-
Mufti GJ, Gore SD, Santini V et al (2009) Influence of karyotype on overall survival in patients with higher-risk myelodysplastic syndrome treated with azacitidine or a conventional care regimen. ASH Annual Meeting Abstracts 114:1755
-
(2009)
ASH Annual Meeting Abstracts
, vol.114
, pp. 1755
-
-
Mufti, G.J.1
Gore, S.D.2
Santini, V.3
-
21
-
-
0035965343
-
Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen
-
Phiel CJ, Zhang F, Huang EY, Guenther MG, Lazar MA, Klein PS (2001) Histone deacetylase is a direct target of valproic acid, a potent anticonvulsant, mood stabilizer, and teratogen. J Biol Chem 276:36734-36741
-
(2001)
J Biol Chem
, vol.276
, pp. 36734-36741
-
-
Phiel, C.J.1
Zhang, F.2
Huang, E.Y.3
Guenther, M.G.4
Lazar, M.A.5
Klein, P.S.6
-
22
-
-
84855487228
-
Phase 2 clinical trial of 5-azacitidine, valproic acid, and all-trans retinoic acid in patients with high-risk acute myeloid leukemia or myelodysplastic syndrome
-
Raffoux E, Cras A, Recher C et al (2010) Phase 2 clinical trial of 5-azacitidine, valproic acid, and all-trans retinoic acid in patients with high-risk acute myeloid leukemia or myelodysplastic syndrome. Oncotarget 1:34-42
-
(2010)
Oncotarget
, Issue.1
, pp. 34-42
-
-
Raffoux, E.1
Cras, A.2
Recher, C.3
-
23
-
-
34548131144
-
CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine
-
DOI 10.1038/sj.leu.2404796, PII 2404796
-
Raj K, John A, Ho A et al (2007) CDKN2B methylation status and isolated chromosome 7 abnormalities predict responses to treatment with 5-azacytidine. Leukemia 21:1937-1944 (Pubitemid 47299967)
-
(2007)
Leukemia
, vol.21
, Issue.9
, pp. 1937-1944
-
-
Raj, K.1
John, A.2
Ho, A.3
Chronis, C.4
Khan, S.5
Samuel, J.6
Pomplun, S.7
Thomas, N.S.B.8
Mufti, G.J.9
-
24
-
-
0002858015
-
Azacitidine (Aza C) in myelodysplastic syndromes (MDS), CALGB studies 8421 and 8 921
-
(meeting abstract)
-
Silverman LR, Holland JF, Demakos EP et al (1994) Azacitidine (Aza C) in myelodysplastic syndromes (MDS), CALGB studies 8421 and 8921. Ann Hematol 68:A12 (meeting abstract)
-
(1994)
Ann Hematol
, vol.68
-
-
Silverman, L.R.1
Holland, J.F.2
Demakos, E.P.3
-
25
-
-
0037093195
-
Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: A study of the cancer and leukemia group B
-
DOI 10.1200/JCO.2002.04.117
-
Silverman LR, Demakos EP, Peterson BL et al (2002) Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B. J Clin Oncol 20:2429-2440 (Pubitemid 34525728)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.10
, pp. 2429-2440
-
-
Silverman, L.R.1
Demakos, E.P.2
Peterson, B.L.3
Kornblith, A.B.4
Holland, J.C.5
Odchimar-Reissig, R.6
Stone, R.M.7
Nelson, D.8
Powell, B.L.9
DeCastro, C.M.10
Ellerton, J.11
Larson, R.A.12
Schiffer, C.A.13
Holland, J.F.14
-
26
-
-
33748474416
-
Further analysis of trials with azacitidine in patients with myelodysplastic syndrome: Studies 8421, 8921, and 9221 by the Cancer and Leukemia Group B
-
DOI 10.1200/JCO.2005.05.4346
-
Silverman LR, McKenzie DR, Peterson BL et al (2006) Further analysis of trials with azacitidine in patients with myelodysplastic syndrome: studies 8421, 8921, and 9221 by the cancer and leukemia group B. J Clin Oncol 24:3895-3903 (Pubitemid 46630737)
-
(2006)
Journal of Clinical Oncology
, vol.24
, Issue.24
, pp. 3895-3903
-
-
Silverman, L.R.1
McKenzie, D.R.2
Peterson, B.L.3
Holland, J.F.4
Backstrom, J.T.5
Beach, C.L.6
Larson, R.A.7
-
27
-
-
34948845116
-
Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome
-
DOI 10.1182/blood-2007-03-078576
-
Soriano AO, Yang H, Faderl S et al (2007) Safety and clinical activity of the combination of 5-azacytidine, valproic acid, and all-trans retinoic acid in acute myeloid leukemia and myelodysplastic syndrome. Blood 110:2302-2308 (Pubitemid 47523148)
-
(2007)
Blood
, vol.110
, Issue.7
, pp. 2302-2308
-
-
Soriano, A.O.1
Yang, H.2
Faderl, S.3
Estrov, Z.4
Giles, F.5
Ravandi, F.6
Cortes, J.7
Wierda, W.G.8
Ouzounian, S.9
Quezada, A.10
Pierce, S.11
Estey, E.H.12
Issa, J.-P.J.13
Kantarjian, H.M.14
Garcia-Manero, G.15
-
28
-
-
33750078985
-
Treatment of acute myelogenous leukemia with outpatient azacitidine
-
DOI 10.1002/cncr.22204
-
Sudan N, Rossetti JM, Shadduck RK, Latsko J, Lech JA, Kaplan RB, Kennedy M, Gryn JF, Faroun Y, Lister J (2006) Treatment of acute myelogenous leukemia with outpatient azacitidine. Cancer 107:1839-1843 (Pubitemid 44582953)
-
(2006)
Cancer
, vol.107
, Issue.8
, pp. 1839-1843
-
-
Sudan, N.1
Rossetti, J.M.2
Shadduck, R.K.3
Latsko, J.4
Lech, J.A.5
Kaplan, R.B.6
Kennedy, M.7
Gryn, J.F.8
Faroun, Y.9
Lister, J.10
-
29
-
-
68049120458
-
Valproic acid at therapeutic plasma levels may increase 5-azacytidine efficacy in higher risk myelodysplastic syndromes
-
Voso MT, Santini V, Finelli C et al (2009) Valproic acid at therapeutic plasma levels may increase 5-azacytidine efficacy in higher risk myelodysplastic syndromes. Clin Cancer Res 15:5002-5007
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5002-5007
-
-
Voso, M.T.1
Santini, V.2
Finelli, C.3
-
30
-
-
42249112646
-
Analysis of mitochondrial DNA in 104 patients with myelodysplastic syndromes
-
DOI 10.1016/j.exphem.2008.01.004, PII S0301472X08000209
-
Wulfert M, Küpper AC, Tapprich C et al (2008) Analysis of mitochondrial DNA in 104 patients with myelodysplastic syndromes. Exp Hematol 36:577-586 (Pubitemid 351551472)
-
(2008)
Experimental Hematology
, vol.36
, Issue.5
, pp. 577-586
-
-
Wulfert, M.1
Kupper, A.C.2
Tapprich, C.3
Bottomley, S.S.4
Bowen, D.5
Germing, U.6
Haas, R.7
Gattermann, N.8
-
31
-
-
20344394418
-
Antileukemia activity of the combination of 5-aza-2′-deoxycytidine with valproic acid
-
DOI 10.1016/j.leukres.2004.11.022, PII S014521260500038X
-
Yang H, Hoshino K, Sanchez-Gonzalez B, Kantarjian H, Garcia-Manero G (2005) Antileukemia activity of the combination of 5-aza-2'-deoxycytidine with valproic acid. Leuk Res 29:739-748 (Pubitemid 40779480)
-
(2005)
Leukemia Research
, vol.29
, Issue.7
, pp. 739-748
-
-
Yang, H.1
Hoshino, K.2
Sanchez-Gonzalez, B.3
Kantarjian, H.4
Garcia-Manero, G.5
|