Emergence of metallo-β-lactamase IMP-14 and VIM-2 in Pseudomonas aeruginosa clinical isolates from a tertiary-level hospital in Thailand

Epidemiology and Infection

Volumn 140, Issue 3, 2012, Pages 539-541

  Piyakul, C ^a   Tiyawisutsri, R ^a   Boonbumrung, K ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

Antibiotic resistance; Pseudomonas

Indexed keywords

AMIKACIN; CEFEPIME; CEFTAZIDIME; CIPROFLOXACIN; COLISTIN; GENTAMICIN; IMIPENEM; LEVOFLOXACIN; MEROPENEM; METALLO BETA LACTAMASE; PIPERACILLIN PLUS TAZOBACTAM; PROTEIN IMP 14; PROTEIN VIM 2; SULPERAZON; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ISOLATE; BLAIMP GENE; BLAVIM GENE; CLONAL VARIATION; DNA SEQUENCE; ENZYME ASSAY; EPSILOMETER TEST; GENE IDENTIFICATION; GENETIC TRAIT; INTEGRON; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PSEUDOMONAS AERUGINOSA; PULSED FIELD GEL ELECTROPHORESIS; THAILAND;

ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; CLUSTER ANALYSIS; CROSS INFECTION; ELECTROPHORESIS, GEL, PULSED-FIELD; HOSPITALS; HUMANS; MICROBIAL SENSITIVITY TESTS; MOLECULAR TYPING; POLYMERASE CHAIN REACTION; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; SEQUENCE ANALYSIS, DNA; THAILAND;

EID: 84856246080     PISSN: 09502688     EISSN: 14694409     Source Type: Journal    
DOI: 10.1017/S0950268811001294     Document Type: Article

References (11)

1. Livermore DM. Multiple mechanisms of antimicrobial resistance in Pseudomonas aeruginosa: our worst nightmare? Clinical Infectious Diseases 2002; 34: 634-640. (Pubitemid 34165326)
2. Shibata N, et al. PCR typing of genetic determinants for metallo-beta-lactamases and integrases carried by gram-negative bacteria isolated in Japan, with focus on the class 3 integron. Journal of Clinical Microbiology 2003; 41: 5407-5413. (Pubitemid 37543224)
3. Boonkerd N, et al. Class 1 integron containing metallo beta-lactamase gene blaIMP-1 in carbapenem-resistant Pseudomonas aeruginosa in Thailand. Journal of Infection and Chemotherapy 2009; 15: 257-261.
4. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing. Nineteenth informational supplement. Document M100-S19. Wayne, PA, CLSI, 2009.
5. Goldberg JB, Ohman DE. Cloning and expression in Pseudomonas aeruginosa of a gene involved in the production of alginate. Journal of Bacteriology 1984; 158: 1115-11121.
6. Ellington MJ, et al. Multiplex PCR for rapid detection of genes encoding acquired metallo-beta-lactamases. Journal of Antimicrobial Chemotherapy 2007; 59: 321-322. (Pubitemid 47072076)
7. Tenover FC, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. Journal of Clinical Microbiology 1995; 33: 2233-2239.
8. Gu B, et al. Prevalence and characterization of class I integrons among Pseudomonas aeruginosa and Acinetobacter baumannii isolates from patients in Nanjing, China. Journal of Clinical Microbiology 2007; 45: 241-243. (Pubitemid 46106436)
9. Lee MF, et al. Molecular characterisation of the metallo-beta-lactamase genes in imipenem-resistant Gram-negative bacteria from a university hospital in southern Taiwan. International Journal of Antimicrobial Agents 2008; 32: 475-480.
10. Collis CM, Hall RM. Expression of antibiotic resistance genes in the integrated cassettes of integrons. Antimicrobial Agents and Chemotherapy 1995; 39: 155-162.
11. Walsh TR, et al. Metallo-beta-lactamases: the quiet before the storm? Clinical Microbiology Reviews 2005; 18: 306-325.