Systemic and renal-specific sympathoinhibition in obesity hypertension

Hypertension

Volumn 59, Issue 2, 2012, Pages 331-338

  Lohmeier, Thomas E ^a   Iliescu, Radu ^a,b   Liu, Boshen ^a   Henegar, Jeffrey R ^a   Maric Bilkan, Christine ^a   Irwin, Eric D ^c  

^a UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

^b GRIGORE T POPA UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^c NORTH MEMORIAL MEDICAL CENTER   (United States)

Author keywords

Baroreflex; Hypertension; Obesity; Renal function; Renal nerves; Renin angiotensin system; Sympathetic nervous system

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CARDIOVASCULAR FUNCTION; DIET; EXPERIMENTAL DOG; GLOMERULUS FILTRATION RATE; HEART RATE; HORMONE RESPONSE; HYPERTENSION; KIDNEY FUNCTION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; OBESITY; PLASMA RENIN ACTIVITY; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; SODIUM EXCRETION; SODIUM INTAKE; SODIUM RETENTION; SYMPATHETIC TONE; TACHYCARDIA;

ANIMALS; BAROREFLEX; BLOOD PRESSURE; BODY WEIGHT; DENERVATION; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; DOGS; GLOMERULAR FILTRATION RATE; HEMODYNAMICS; HYPERTENSION; KIDNEY; MALE; OBESITY; RENIN; SYMPATHETIC NERVOUS SYSTEM;

EID: 84856243152     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.111.185074     Document Type: Article

References (45)

1. Esler M, Straznicky N, Eikelis N, Masuo K, Lambert G, Lambert E. Mechanisms of sympathetic activation in obesity-related hypertension. Hypertension. 2006;48:787-796. (Pubitemid 44610980)
2. Hall JE, da Dilva AA, Brandon E, Stec DE, Ying Z, Jones DW. Pathophysiology of obesity-induced hypertension and target organ damage. In: Lip GYH, Hall JE, eds. Comprehensive Hypertension. New York: Elsevier; 2007:447-468.
3. Lohmeier, TE, Iliescu R. Chronic lowering of blood pressure by carotid baroreflex activation: mechanisms and potential for hypertension therapy. Hypertension. 2011;57:880-886.
4. Wustmann K, Kucera JP, Scheffers I, Mohaupt M, Kroon AA, de Leeuw PW, Schmidli J, Allemann Y, Delacretaz E. Effects of chronic baroreceptor stimulation on the autonomic cardiovascular regulation in patients with drug-resistant arterial hypertension. Hypertension. 2009;54:530-536.
5. Heusser K, Tank J, Engeli S, Diedrich A, Menne J, Eckert S, Peters T, Sweep FCGJ, Haller H, Pichlmaier, Luft F, Jordan J. Carotid baroreceptor stimulation, sympathetic activity, baroreflex function, and blood pressure in hypertensive patients. Hypertension. 2010;55:619-626.
6. Scheffers IJM, Kroon AA, Schmidli J, Jordan J, Tordoir JJM, Mohaupt MG, Luft FC, Haller H, Menne J, Engeli S, Ceral J, Eckert S, Erglis A, Narkiewicz K, Philipp T, de Leeuw PW. Novel baroreflex activation therapy in resistant hypertension. J Am Coll Cardiol. 2010;56:1254-1258.
7. Bisognano JD, Bakris G, Nadim MK, Sanchez L, Kroon AA, Schafer J, de Leeuw PW, Sica DA. Baroreflex activation therapy lowers blood pressure in patients with resistant hypertension: results from the doubleblind, randomized, placebo-controlled Rheos Pivotal trial. J Am Coll Cardiol. 2011;58:765-773.
8. Guyton AC. Arterial Pressure and Hypertension. Philadelphia, PA: Saunders; 1980.
9. Cowley AW Jr. Long-term control of arterial blood pressure. Physiol Rev. 1992;72:231-300.
10. Lohmeier TE, Drummond HA. The baroreflex in the pathogenesis of hypertension. In: Lip GYH, Hall JE, eds. Comprehensive Hypertension. New York: Elsevier; 2007:265-279.
11. Lohmeier TE, Hildebrandt DA, Warren S, May PJ, Cunningham JT. Recent insights into the interactions between the baroreflex and the kidneys in hypertension. Am J Physiol Regulatory Integrative Comp Physiol. 2005;288:R828-R836. (Pubitemid 40404155)
12. Lohmeier TE, Lohmeier JR, Haque A, Hildebrandt DA. Baroreflexes prevent neurally-induced sodium retention in angiotensin hypertension. Am J Physiol Regulatory Integrative Comp Physiol. 2000;279:R1437-R1448.
13. Barrett CJ, Guild S-J, Ramchandra R, Malpas SC. Baroreceptor denervation prevents sympathoinhibition during angiotensin II-induced hypertension. Hypertension. 2005;46:1-5.
14. Krum H, Schlaich M, Whitbourn R, Sobotka PA, Sadowski J, Bartus K, Kapelak B, Walton A, Sievert H, Thambar S, Abraham WT, Esler M. Catheter-based renal sympathetic denervation for resistant hypertension: a multicentre safety and proof-of-principle cohort study. Lancet. 2009;373:1275-1281.
15. Simplicity HTN-2 Investigators. Renal sympathetic denervation in patients with treatment resistant hypertension (the Symplicity HTN-2 Trial): a randomized controlled trial. Lancet. 2011;376:1903-1909.
16. Schlaich MP, Sobotka PA, Krum H, Lambert E, Esler MD. Renal sympathetic-nerve ablation for uncontrolled hypertension. N Engl J Med. 2009;361:932-934.
17. Rocchini AP. Moorehead CP, De Remer S, Bondie D. Pathogenesis of weight-related changes in blood pressure in dogs. Hypertension. 1989;13:922-928. (Pubitemid 19157991)
18. Hall JE, Brands MW, Dixon WN, Smith MJ Jr. Obesity-induced hypertension: renal function and systemic hemodynamics. Hypertension. 1993;22:292-299. (Pubitemid 23254076)
19. Lohmeier TE, Dwyer TM, Irwin ED, Rossing MA, Kieval RS. Prolonged activation of the baroreflex abolishes obesity-induced hypertension. Hypertension. 2007;49:1307-1314. (Pubitemid 46809373)
20. Calhoun DA, Jones D, Textor S, Goff DC, Murphy TP, Toto RD, White A, Cushman WC, White W, Sica D, Ferdinand K, Giles TD, Falkner B, Carey RM. Resistant hypertension: diagnosis, evaluation, and treatment: a scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. Hypertension. 2008;117:e510-e526.
21. Persell SD. Prevalence of resistant hypertension in the United States, 2003-2008. Hypertension. 2011;57:1076-1080.
22. Lohmeier TE, Irwin ED, Rossing MA, Sedar DJ, Kieval RS. Prolonged activation of the baroreflex produces sustained hypotension. Hypertension. 2004;43:306-311. (Pubitemid 38174130)
23. Lohmeier TE, Iliescu R, Dwyer TM, Irwin ED, Cates AW, Rossing MA. Sustained suppression of sympathetic activity and arterial pressure during chronic activation of the carotid baroreflex. Am J Physiol Heart Circ Physiol. 2010;299:H402-H409.
24. Lohmeier TE, Reinhart GA, Mizelle HL, Montani J-P, Hester RL, Hord CE Jr, Hildebrandt DA. Influence of the renal nerves on sodium excretion during progressive reductions in cardiac output. Am J Physiol Regulatory Integrative Comp Physiol. 1995;269:R678-R690.
25. Reinhart GA, Lohmeier TE, Hord CE Jr. Hypertension induced by chronic renal adrenergic stimulation is angiotensin dependent. Hypertension. 1995;25:940-949.
26. Lohmeier TE, Dwyer TM, Hildebrandt DA, Irwin ED, Rossing MA, Serdar DJ, Kieval RS. Influence of prolonged baroreflex activation on arterial pressure in angiotensin hypertension. Hypertension. 2005;46:1194-1200. (Pubitemid 41533025)
27. Holmes C, Eisenhofer G, Goldstein DS. Improved assay for plasma dihydroxyphenylacetic acid and other catechols using high-performance liquid chromatography with electrochemical detection. J Chromatogr B Biomed Appl. 1994;653:131-138. (Pubitemid 24085051)
28. Grassi G, Seravalle G, Cattaneo BM, Bolla GB, Lanfranchi A, Colombo M, Giannattasio C, Brunani A, Cavagnini F, Mancia M. Sympathetic activation in obese normotensive subjects. Hypertension. 1995;25:560-563.
29. Grassi G, Seravalle G, Dell'Oro R, Turri C, Bolla GB, Mancia G. Adrenergic and reflex abnormalities in obesity-related hypertension. Hypertension. 2000;36:538-542.
30. Shibao C, Gamboa A, Diedrich A, Ertl AC, Chen KY, Byrne DW, Farley G, Paranjape SY, Davis SN, Biaggioni I. Autonomic contribution to blood pressure and metabolism in obesity. Hypertension. 2007;49:27-33. (Pubitemid 46360337)
31. Vaz M, Jennings G, Turner A, Cox H. Lambert G, Esler M. Regional sympathetic nervous activity and oxygen consumption in obese normotensive human subjects. Circulation. 1997;96:3423-3429. (Pubitemid 27513415)
32. Rumantir MS, Vaz M, Jennings GL, Collier G, Kaye DM, Seals DR, Wiesner GH, Brunner-La Rocca HP, Esler MD. Neural mechanisms in human obesity-related hypertension. J Hypertens. 1999;17:1125-1133. (Pubitemid 29389560)
33. Kassab S, Kato T, Wilkins C, Chen R, Hall JE, Granger JP. Renal denervation attenuates the sodium retention and hypertension associated with obesity. Hypertension. 1995;25:893-897.
34. Esler M, Jennings G, Lambert G, Meredith I, Horne M, Eisenhofer G. Overflow of catecholamine neurotransmitters to the circulation: source, fate, and functions. Physiol Rev. 1990;70:963-985. (Pubitemid 20364820)
35. Grassi G, Facchini A, Trevano FQ, Dell'Oro R, Arenare F, Tana F, Bolla G, Monzani A, Robuschi M, Mancia G. Obstructive sleep apnea-dependent and-independent adrenergic activation in obesity. Hypertension. 2005;46:321-325. (Pubitemid 41099164)
36. Boustany CM, Bharadwaj K, Daugherty A, Brown DR, Randall DC, Cassis LA. Activation of the systemic and adipose renin-angiotensin system in rats with diet-induced obesity and hypertension. Am J Physiol Regulatory Integrative Comp Physiol. 2004;287:R943-R949. (Pubitemid 39280483)
37. Grassi G, Seravalle G, Quarti-Trevano F, Dell'Oro R, Bolla G, Mancia G. Effects of hypertension and obesity on the sympathetic activation of heart failure patients. Hypertension. 2003;42:873-877. (Pubitemid 37413723)
38. Reisen E, Weir MR, Falkner B, Hutchinson HG, Anzalone DA, Tuck ML. Lisinopril versus hydrochlorothiazide in obese hypertensive patients. Hypertension. 1997;30:140-145.
39. Boustany CM, Brown DR, Randall DC, Cassis LA. At1-receptor antagonism reverses the blood pressure elevation associated with dietinduced obesity. Am J Physiol Regulatory Integrative Comp Physiol. 2005;289:R181-R186. (Pubitemid 40874974)
40. Van Vliet BN, Hall JE, Mizelle HL, Montani J-P, Smith MJ Jr. Reduced parasympathetic control of heart rate in obese dogs. Am J Physiol Heart Circ Physiol. 1995;269:H629-H637.
41. Truett AA, Borne AT, Poincot MA, West DB. Autonomic control of blood pressure and heart rate in obese hypertensive dogs. Am J Physiol Regulatory Integrative Comp Physiol. 1996;270:R541-R549.
42. Di Bona GF, Kopp UC. Neural control of renal function. Physiol Rev. 1997;77:75-197. (Pubitemid 27069290)
43. Thomson SC, Vallon V, Blantz RC. Kidney function in early diabetes: the tubular hypothesis of glomerular filtration. Am J Physiol Renal Physiol. 2003;286:F8-F15.
44. Hall JE, Summers RL, Brands MW, Keen H, Alonso-Galicia M. Resistance to metabolic cations of insulin and its role in hypertension. Am J Hypertens. 1994;7:772-788. (Pubitemid 24269768)
45. Mahfoud F, Schlaich M, Kindermann I, Ukena C, Cremers B, Brandt MC, Hoppe UC, Vonend O, Rump LC, Sobotka PA, Krum H, Esler M, Bohm M. Effect of renal sympathetic denervation on glucose metabolism in patients with resistant hypertension: a pilot study. Circulation. 2011;123:1940-1946.