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Volumn 205, Issue 4, 2012, Pages 621-630

The prostanoid 15-Deoxy-Δ 12,14-prostaglandin-J2 reduces lung inflammation and protects mice against lethal influenza infection

Author keywords

[No Author keywords available]

Indexed keywords

15 DEOXY DELTA12,14 PROSTAGLANDIN J2; 2 CHLORO 5 NITROBENZANILIDE; CHEMOKINE; CYTOKINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA ANTAGONIST; PROSTANOID;

EID: 84856242482     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1093/infdis/jir804     Document Type: Article
Times cited : (55)

References (48)
  • 2
    • 77749282915 scopus 로고    scopus 로고
    • Delayed clearance of viral load and marked cytokine activation in severe cases of pandemic H1N1 2009 influenza virus infection
    • To KK, Hung IF, Li IW, et al. Delayed clearance of viral load and marked cytokine activation in severe cases of pandemic H1N1 2009 influenza virus infection. Clin Infect Dis 2010; 50:850-9.
    • (2010) Clin Infect Dis , vol.50 , pp. 850-859
    • To, K.K.1    Hung, I.F.2    Li, I.W.3
  • 3
    • 73849101100 scopus 로고    scopus 로고
    • Lung pathology in fatal novel human influenza A (H1N1) infection
    • Mauad T, Hajjar LA, Callegari GD, et al. Lung pathology in fatal novel human influenza A (H1N1) infection. Am J Respir Crit Care Med 2010; 181:72-9.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 72-79
    • Mauad, T.1    Hajjar, L.A.2    Callegari, G.D.3
  • 4
    • 53749084847 scopus 로고    scopus 로고
    • Insights into inflammation and influenza
    • Simmons C, Farrar J. Insights into inflammation and influenza. N Engl J Med 2008; 359:1621-3.
    • (2008) N Engl J Med , vol.359 , pp. 1621-1623
    • Simmons, C.1    Farrar, J.2
  • 7
    • 50849097044 scopus 로고    scopus 로고
    • H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice
    • Perrone LA, Plowden JK, Garcia-Sastre A, Katz JM, Tumpey TM. H5N1 and 1918 pandemic influenza virus infection results in early and excessive infiltration of macrophages and neutrophils in the lungs of mice. PLoS Pathog 2008; 4:e1000115.
    • (2008) PLoS Pathog , vol.4
    • Perrone, L.A.1    Plowden, J.K.2    Garcia-Sastre, A.3    Katz, J.M.4    Tumpey, T.M.5
  • 8
    • 67649126476 scopus 로고    scopus 로고
    • Confronting the next influenza pandemic with antiinflammatory and immunomodulatory agents: Why they are needed and how they might work
    • Fedson DS. Confronting the next influenza pandemic with antiinflammatory and immunomodulatory agents: why they are needed and how they might work. Influenza Other Respi Viruses 2009; 3: 129-42.
    • (2009) Influenza Other Respi Viruses , vol.3 , pp. 129-142
    • Fedson, D.S.1
  • 9
    • 33646252267 scopus 로고    scopus 로고
    • Influenza ("bird flu"), inflammation and antiinflammatory/ analgesic drugs
    • Rainsford KD. Influenza ("bird flu"), inflammation and antiinflammatory/analgesic drugs. Inflammopharmacology 2006; 14:2-9.
    • (2006) Inflammopharmacology , vol.14 , pp. 2-9
    • Rainsford, K.D.1
  • 10
    • 59049093098 scopus 로고    scopus 로고
    • The influenza virus enigma
    • Salomon R, Webster RG. The influenza virus enigma. Cell 2009; 136: 402-10.
    • (2009) Cell , vol.136 , pp. 402-410
    • Salomon, R.1    Webster, R.G.2
  • 12
    • 65249145291 scopus 로고    scopus 로고
    • TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection
    • Aldridge JR Jr, Moseley CE, Boltz DA, et al. TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection. Proc Natl Acad Sci USA 2009; 106:5306-11.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 5306-5311
    • Aldridge Jr., J.R.1    Moseley, C.E.2    Boltz, D.A.3
  • 16
    • 0031888958 scopus 로고    scopus 로고
    • PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
    • DOI 10.1038/34184
    • Jiang C, Ting AT, Seed B. PPAR-gamma agonists inhibit production of monocyte inflammatory cytokines. Nature 1998; 391:82-6. (Pubitemid 28079219)
    • (1998) Nature , vol.391 , Issue.6662 , pp. 82-86
    • Jiang, C.1    Ting, A.T.2    Seed, B.3
  • 18
    • 33846692486 scopus 로고    scopus 로고
    • Differential involvement of NF-κB and MAP kinase pathways in the generation of inflammatory cytokines by human neutrophils
    • DOI 10.1189/jlb.0806536
    • Cloutier A, Ear T, Blais-Charron E, Dubois CM, McDonald PP. Differential involvement of NF-kappaB and MAP kinase pathways in the generation of inflammatory cytokines by human neutrophils. J Leukoc Biol 2007; 81:567-77. (Pubitemid 46198409)
    • (2007) Journal of Leukocyte Biology , vol.81 , Issue.2 , pp. 567-577
    • Cloutier, A.1    Ear, T.2    Blais-Charron, E.3    Dubois, C.M.4    McDonald, P.P.5
  • 19
    • 4143114777 scopus 로고    scopus 로고
    • 2-mediated ERK signaling inhibits gram-negative bacteria-induced RelA phosphorylation and interleukin-6 gene expression in intestinal epithelial cells through modulation of protein phosphatase 2A activity
    • DOI 10.1074/jbc.M405032200
    • Ruiz PA, Kim SC, Sartor RB, Haller D. 15-Deoxy-delta12,14-prostaglandin J2-mediated ERK signaling inhibits gram-negative bacteria-induced RelA phosphorylation and interleukin-6 gene expression in intestinal epithelial cells through modulation of protein phosphatase 2A activity. J Biol Chem 2004; 279:36103-11. (Pubitemid 39100618)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.34 , pp. 36103-36111
    • Ruiz, P.A.1    Kim, S.C.2    Sartor, R.B.3    Haller, D.4
  • 20
    • 28444455582 scopus 로고    scopus 로고
    • PPAR-γ agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-κB pathways
    • DOI 10.1182/blood-2004-12-4709
    • Appel S, Mirakaj V, Bringmann A,Weck MM, Grunebach F, Brossart P. PPAR-gamma agonists inhibit toll-like receptor-mediated activation of dendritic cells via the MAP kinase and NF-kappaB pathways. Blood 2005; 106:3888-94. (Pubitemid 41739028)
    • (2005) Blood , vol.106 , Issue.12 , pp. 3888-3894
    • Appel, S.1    Mirakaj, V.2    Bringmann, A.3    Weck, M.M.4    Grunebach, F.5    Brossart, P.6
  • 23
    • 0038121646 scopus 로고    scopus 로고
    • 2, attenuates the severity of cerulein-induced acute pancreatitis
    • DOI 10.1097/00006676-200307000-00009
    • Hashimoto K, Ethridge RT, Saito H, Rajaraman S, Evers BM. The PPARgamma ligand, 15d-PGJ2, attenuates the severity of ceruleininduced acute pancreatitis. Pancreas 2003; 27:58-66. (Pubitemid 36775980)
    • (2003) Pancreas , vol.27 , Issue.1 , pp. 58-66
    • Hashimoto, K.1    Ethridge, R.T.2    Saito, H.3    Rajaraman, S.4    Evers, B.M.5
  • 24
    • 0346366979 scopus 로고    scopus 로고
    • 2 and Ciglitazone, Reduce Systemic Inflammation in Polymicrobial Sepsis by Modulation of Signal Transduction Pathways
    • Zingarelli B, Sheehan M, Hake PW, O'Connor M, Denenberg A, Cook JA. Peroxisome proliferator activator receptor-gamma ligands, 15-deoxy-delta(12,14)- prostaglandin J2 and ciglitazone, reduce systemic inflammation in polymicrobial sepsis by modulation of signal transduction pathways. J Immunol 2003; 171:6827-37. (Pubitemid 37532118)
    • (2003) Journal of Immunology , vol.171 , Issue.12 , pp. 6827-6837
    • Zingarelli, B.1    Sheehan, M.2    Hake, P.W.3    O'Connor, M.4    Denenberg, A.5    Cook, J.A.6
  • 28
    • 0034610759 scopus 로고    scopus 로고
    • Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase
    • DOI 10.1038/47520
    • Rossi A, Kapahi P, Natoli G, et al. Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase. Nature 2000; 403:103-8. (Pubitemid 30038530)
    • (2000) Nature , vol.403 , Issue.6765 , pp. 103-108
    • Rossi, A.1    Kapahi, P.2    Natoli, G.3    Takahashi, T.4    Chen, Y.5    Karin, M.6    Santoro, M.G.7
  • 30
    • 0035929592 scopus 로고    scopus 로고
    • 15-Deoxy-delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit
    • Cernuda-Morollon E, Pineda-Molina E, Canada FJ, Perez-Sala D. 15-Deoxy-delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit. J Biol Chem 2001; 276:35530-6.
    • (2001) J Biol Chem , vol.276 , pp. 35530-35536
    • Cernuda-Morollon, E.1    Pineda-Molina, E.2    Canada, F.J.3    Perez-Sala, D.4
  • 31
    • 36049034344 scopus 로고    scopus 로고
    • Anti-inflammatory actions of PPAR ligands: New insights on cellular and molecular mechanisms
    • DOI 10.1016/j.it.2007.09.003, PII S147149060700244X
    • Straus DS, Glass CK. Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms. Trends Immunol 2007; 28:551-8. (Pubitemid 350101420)
    • (2007) Trends in Immunology , vol.28 , Issue.12 , pp. 551-558
    • Straus, D.S.1    Glass, C.K.2
  • 32
    • 0035710746 scopus 로고    scopus 로고
    • -ΔΔCT method
    • DOI 10.1006/meth.2001.1262
    • Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 2001; 25:402-8. (Pubitemid 34164012)
    • (2001) Methods , vol.25 , Issue.4 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 35
    • 0037038866 scopus 로고    scopus 로고
    • Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: A mechanism for the unusual severity of human disease?
    • DOI 10.1016/S0140-6736(02)11772-7
    • Cheung CY, Poon LL, Lau AS, et al. Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease? Lancet 2002; 360:1831-7. (Pubitemid 35449422)
    • (2002) Lancet , vol.360 , Issue.9348 , pp. 1831-1837
    • Cheung, C.Y.1    Poon, L.L.M.2    Lau, A.S.3    Luk, W.4    Lau, Y.L.5    Shortridge, K.F.6    Gordon, S.7    Guan, Y.8    Peiris, J.S.M.9
  • 36
    • 0034807183 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor reduces the severity of virus-specific lung immunopathology
    • DOI 10.1002/1521-4141(200109)31:9<2566::AID-IMMU2566>3.0.CO;2-L
    • Hussell T, Pennycook A, Openshaw PJ. Inhibition of tumor necrosis factor reduces the severity of virus-specific lung immunopathology. Eur J Immunol 2001; 31:2566-73. (Pubitemid 32898723)
    • (2001) European Journal of Immunology , vol.31 , Issue.9 , pp. 2566-2573
    • Hussell, T.1    Pennycook, A.2    Openshaw, P.J.M.3
  • 37
    • 77956987443 scopus 로고    scopus 로고
    • Mice lacking both TNF and IL-1 receptors exhibit reduced lung inflammation and delay in onset of death following infection with a highly virulent H5N1 virus
    • Perrone LA, Szretter KJ, Katz JM, Mizgerd JP, Tumpey TM. Mice lacking both TNF and IL-1 receptors exhibit reduced lung inflammation and delay in onset of death following infection with a highly virulent H5N1 virus. J Infect Dis 2010; 202:1161-70.
    • (2010) J Infect Dis , vol.202 , pp. 1161-1170
    • Perrone, L.A.1    Szretter, K.J.2    Katz, J.M.3    Mizgerd, J.P.4    Tumpey, T.M.5
  • 38
    • 0033872286 scopus 로고    scopus 로고
    • Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virus
    • Dawson TC, BeckMA, Kuziel WA, Henderson F, Maeda N. Contrasting effects of CCR5 and CCR2 deficiency in the pulmonary inflammatory response to influenza A virus. Am J Pathol 2000; 156:1951-9. (Pubitemid 30641764)
    • (2000) American Journal of Pathology , vol.156 , Issue.6 , pp. 1951-1959
    • Dawson, T.C.1    Beck, M.A.2    Kuziel, W.A.3    Henderson, F.4    Maeda, N.5
  • 39
    • 79251534355 scopus 로고    scopus 로고
    • CCR2-antagonist prophylaxis reduces pulmonary immune pathology and markedly improves survival during influenza infection
    • Lin KL, Sweeney S, Kang BD, Ramsburg E, Gunn MD. CCR2-antagonist prophylaxis reduces pulmonary immune pathology and markedly improves survival during influenza infection. J Immunol 2011; 186: 508-15.
    • (2011) J Immunol , vol.186 , pp. 508-515
    • Lin, K.L.1    Sweeney, S.2    Kang, B.D.3    Ramsburg, E.4    Gunn, M.D.5
  • 40
    • 45849109558 scopus 로고    scopus 로고
    • Delayed antiviral plus immunomodulator treatment still reduces mortality in mice infected by high inoculum of influenza A/H5N1 virus
    • Zheng BJ, Chan KW, Lin YP, et al. Delayed antiviral plus immunomodulator treatment still reduces mortality in mice infected by high inoculum of influenza A/H5N1 virus. Proc Natl Acad Sci USA 2008; 105:8091-6.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 8091-8096
    • Zheng, B.J.1    Chan, K.W.2    Lin, Y.P.3
  • 41
    • 78149454651 scopus 로고    scopus 로고
    • Treating viral exacerbations of chronic obstructive pulmonary disease: Insights from a mouse model of cigarette smoke and H1N1 influenza infection
    • Bauer CM, Zavitz CC, Botelho FM, et al. Treating viral exacerbations of chronic obstructive pulmonary disease: insights from a mouse model of cigarette smoke and H1N1 influenza infection. PLoS One 2010; 5:e13251.
    • (2010) PLoS One , vol.5
    • Bauer, C.M.1    Zavitz, C.C.2    Botelho, F.M.3
  • 42
    • 77955860573 scopus 로고    scopus 로고
    • PPAR-gamma activation as an anti-inflammatory therapy for respiratory virus infections
    • Bassaganya-Riera J, Song R, Roberts PC, Hontecillas R. PPAR-gamma activation as an anti-inflammatory therapy for respiratory virus infections. Viral Immunol 2010; 23:343-52.
    • (2010) Viral Immunol , vol.23 , pp. 343-352
    • Bassaganya-Riera, J.1    Song, R.2    Roberts, P.C.3    Hontecillas, R.4
  • 43
    • 77955796417 scopus 로고    scopus 로고
    • Peroxisome proliferatoractivated receptor and AMP-activated protein kinase agonists protect against lethal influenza virus challenge in mice
    • Moseley CE, Webster RG, Aldridge JR. Peroxisome proliferatoractivated receptor and AMP-activated protein kinase agonists protect against lethal influenza virus challenge in mice. Influenza Other Respi Viruses 2010; 4:307-11.
    • (2010) Influenza Other Respi Viruses , vol.4 , pp. 307-311
    • Moseley, C.E.1    Webster, R.G.2    Aldridge, J.R.3
  • 44
    • 33749506249 scopus 로고    scopus 로고
    • 2 and ciglitazone induce human B lymphocyte and B cell lymphoma apoptosis by PPARγ-independent mechanisms
    • Ray DM, Akbiyik F, Phipps RP. The peroxisome proliferatoractivated receptor gamma (PPARgamma) ligands 15-deoxy-delta12, 14-prostaglandin J2 and ciglitazone induce human B lymphocyte and B cell lymphoma apoptosis by PPARgamma-independent mechanisms. J Immunol 2006; 177:5068-76. (Pubitemid 44527577)
    • (2006) Journal of Immunology , vol.177 , Issue.8 , pp. 5068-5076
    • Ray, D.M.1    Akbiyik, F.2    Phipps, R.P.3
  • 45
    • 34347345089 scopus 로고    scopus 로고
    • Mechanism of thiazolidinedione-dependent cell death in Jurkat T cells
    • DOI 10.1124/mol.107.034371
    • Soller M, Drose S, Brandt U, Brune B, von Knethen A. Mechanism of thiazolidinedione-dependent cell death in Jurkat T cells. Mol Pharmacol 2007; 71:1535-44. (Pubitemid 47010906)
    • (2007) Molecular Pharmacology , vol.71 , Issue.6 , pp. 1535-1544
    • Soller, M.1    Drose, S.2    Brandt, U.3    Brune, B.4    Von Knethen, A.5
  • 47
    • 33644825094 scopus 로고    scopus 로고
    • Peroxisome-proliferator-activated receptor-γ agonists inhibit the release of proinflammatory cytokines from RSV-infected epithelial cells
    • DOI 10.1016/j.virol.2005.11.009, PII S0042682205007567
    • Arnold R, Konig W. Peroxisome-proliferator-activated receptorgamma agonists inhibit the release of proinflammatory cytokines from RSV-infected epithelial cells. Virology 2006; 346:427-39. (Pubitemid 43357886)
    • (2006) Virology , vol.346 , Issue.2 , pp. 427-439
    • Arnold, R.1    Konig, W.2


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