Promoter characterization and genomic organization of the human X11β gene APBA2

NeuroReport

Volumn 23, Issue 3, 2012, Pages 146-151

  Hao, Yan ^a   Chai, Ka Ho ^a   McLoughlin, Declan M ^d   Chan, Ho Yin Edwin ^a,b,c   Lau, Kwok Fai ^a,b,c  

^a Biochemistry Program   (Hong Kong)

^b Molecular Biotechnology Program   (Hong Kong)

^c CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^d TRINITY COLLEGE DUBLIN   (Ireland)

Author keywords

Alzheimer's disease; APBA2; Promoter, X11

Indexed keywords

AMYLOID BETA A4 PRECURSOR PROTEIN BINDING FAMILY A MEMBER 2; BINDING PROTEIN; COMPLEMENTARY DNA; CPG OLIGODEOXYNUCLEOTIDE; NERVE PROTEIN; PROTEIN X11BETA; TRANSCRIPTION FACTOR PAX5; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; DNA METHYLATION; DNA SEQUENCE; GENE MAPPING; GENE STRUCTURE; GENETIC TRANSCRIPTION; GENOME ANALYSIS; GENOMICS; MUTAGENESIS; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; RAT;

BASE SEQUENCE; BINDING SITES; BRAIN; CADHERINS; CARRIER PROTEINS; DNA METHYLATION; GENE EXPRESSION REGULATION; GENOME, HUMAN; HUMANS; MOLECULAR SEQUENCE DATA; MUTAGENESIS; NERVE TISSUE PROTEINS; PROMOTER REGIONS, GENETIC; TRANSCRIPTION, GENETIC;

EID: 84856242479     PISSN: 09594965     EISSN: 1473558X     Source Type: Journal    
DOI: 10.1097/WNR.0b013e32834f1934     Document Type: Article

References (25)

1. Hardy J. The amyloid hypothesis for Alzheimer's disease: a critical reappraisal. J Neurochem 2009; 110:1129-1134.
2. Tomita S, Ozaki T, Taru H, Oguchi S, Takeda S, Yagi Y, et al. Interaction of a neuron-specific protein containing PDZ domains with Alzheimer's amyloid precursor protein. J Biol Chem 1999; 274:2243-2254.
3. Okamoto M, Sudhof TC. Mints, Munc18-interacting proteins in synaptic vesicle exocytosis. J Biol Chem 1997; 272:31459-31464. (Pubitemid 28013285)
4. Rogelj B, Mitchell JC, Miller CC, McLoughlin DM. The X11/Mint family of adaptor proteins. Brain Res Brain Res Rev 2006; 52:305-315. (Pubitemid 44291809)
5. Kondo M, Shiono M, Itoh G, Takei N, Matsushima T, Maeda M, et al. Increased amyloidogenic processing of transgenic human APP in X11-like deficient mouse brain. Mol Neurodegener 2010; 5:35.
6. Mitchell JC, Ariff BB, Yates DM, Lau KF, Perkinton MS, Rogelj B, et al. X11b rescues memory and long-term potentiation deficits in Alzheimer's disease APPswe Tg2576 mice. Hum Mol Genet 2009; 18:4492-4500.
7. Hill K, Li Y, Bennett M, McKay M, Zhu X, Shern J, et al. Munc18 interacting proteins: ADP-ribosylation factor-dependent coat proteins that regulate the traffic of beta-Alzheimer's precursor protein. J Biol Chem 2003; 278:36032-36040. (Pubitemid 37139923)
8. Hase M, Yagi Y, Taru H, Tomita S, Sumioka A, Hori K, et al. Expression and characterization of the Drosophila X11-like/Mint protein during neural development. J Neurochem 2002; 81:1223-1232. (Pubitemid 34809256)
9. McLoughlin DM, Irving NG, Brownlees J, Brion JP, Leroy K, Miller CC. Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease. Eur J Neurosci 1999; 11:1988-1994. (Pubitemid 29240564)
10. Nakajima Y, Okamoto M, Nishimura H, Obata K, Kitano H, Sugita M, et al. Neuronal expression of mint1 and mint2, novel multimodular proteins, in adult murine brain. Brain Res Mol Brain Res 2001; 92:27-42. (Pubitemid 32718702)
11. Yu HT, Chan WW, Chai KH, Lee CW, Chang RC, Yu MS, et al. Transcriptional regulation of human FE65, a ligand of Alzheimer's disease amyloid precursor protein, by Sp1. J Cell Biochem 2010; 109: 782-793.
12. Lau KF, Chan WM, Perkinton MS, Tudor EL, Chang RC, Chan HY, et al. Dexras1 Interacts with FE65 to Regulate FE65-Amyloid Precursor Proteindependent Transcription. J Biol Chem 2008; 283:34728-34737.
13. Duclos F, Boschert U, Sirugo G, Mandel JL, Hen R, Koenig M. Gene in the region of the Friedreich ataxia locus encodes a putative transmembrane protein expressed in the nervous system. Proc Natl Acad Sci USA 1993; 90:109-113. (Pubitemid 23010259)
14. Blanco G, Irving NG, Brown SD, Miller CC, McLoughlin DM. Mapping of the human and murine X11-like genes (APBA2 and apba2), the murine Fe65 gene (Apbb1), and the human Fe65-like gene (APBB2): genes encoding phosphotyrosine-binding domain proteins that interact with the Alzheimer's disease amyloid precursor protein. Mamm Genome 1998; 9:473-475. (Pubitemid 28334403)
15. Prestridge DS. Predicting Pol II promoter sequences using transcription factor binding sites. J Mol Biol 1995; 249:923-932.
16. Zhang W, Lilja L, Bark C, Berggren PO, Meister B. Mint1, a Munc-18-interacting protein, is expressed in insulin-secreting beta-cells. Biochem Biophys Res Commun 2004; 320:717-721. (Pubitemid 38887202)
17. Van-Groen T. DNA methylation and Alzheimer's disease. In: Trygve O Tollefsbol, editor. Epigenetics of aging, part V. 2010. pp. 315-326.
18. Jacobs EH, Williams RJ, Francis PT. Cyclin-dependent kinase 5, Munc18a and Munc18-interacting protein 1/X11alpha protein up-regulation in Alzheimer's disease. Neuroscience 2006; 138:511-522. (Pubitemid 43255561)
19. Thompson JA, Ziman M. Pax genes during neural development and their potential role in neuroregeneration. Prog Neurobiol 2011; 95:334-351.
20. Morrison AM, Nutt SL, Thevenin C, Rolink A, Busslinger M. Loss-and gain-of-function mutations reveal an important role of BSAP (Pax-5) at the start and end of B cell differentiation. Semin Immunol 1998; 10: 133-142. (Pubitemid 28339783)
21. Souabni A, Cobaleda C, Schebesta M, Busslinger M. Pax5 promotes B lymphopoiesis and blocks T cell development by repressing Notch1. Immunity 2002; 17:781-793. (Pubitemid 35477797)
22. Holmes ML, Carotta S, Corcoran LM, Nutt SL. Repression of Flt3 by Pax5 is crucial for B-cell lineage commitment. Genes Dev 2006; 20:933-938.
23. Sutcliffe JS, Han MK, Amin T, Kesterson RA, Nurmi EL. Partial duplication of the APBA2 gene in chromosome 15q13 corresponds to duplicon structures. BMC Genomics 2003; 4:15.
24. Bradnam KR, Korf I. Longer first introns are a general property of eukaryotic gene structure. PLoS One 2008; 3:e3093.
25. Jeon JS, Lee S, Jung KH, Jun SH, Kim C, An G. Tissue-preferential expression of a rice alpha-tubulin gene, OsTubA1, mediated by the first intron. Plant Physiol 2000; 123:1005-1014. (Pubitemid 30466852)