메뉴 건너뛰기




Volumn 233, Issue 1, 2012, Pages 145-153

A combined in vivo neurochemical and electrophysiological analysis of the effect of high-frequency stimulation of the subthalamic nucleus on 5-HT transmission

Author keywords

5 HT; Deep brain stimulation; Depression; In vivo electrophysiology; Microdialysis; Parkinson's disease; Subthalamic nucleus

Indexed keywords

5 HYDROXYINDOLEACETIC ACID; DOPAMINE; SEROTONIN;

EID: 84856231454     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2011.08.027     Document Type: Article
Times cited : (37)

References (65)
  • 1
    • 0142195828 scopus 로고    scopus 로고
    • Neurochemical and anatomical identification of fast- and slow-firing neurones in the rat dorsal raphe nucleus using juxtacellular labelling methods in vivo
    • Allers K.A., Sharp T. Neurochemical and anatomical identification of fast- and slow-firing neurones in the rat dorsal raphe nucleus using juxtacellular labelling methods in vivo. Neuroscience 2003, 122:193-204.
    • (2003) Neuroscience , vol.122 , pp. 193-204
    • Allers, K.A.1    Sharp, T.2
  • 2
    • 35348980734 scopus 로고    scopus 로고
    • Psychiatric and neuropsychiatric adverse events associated with deep brain stimulation: a meta-analysis of ten years' experience
    • Appleby B.S., Duggan P.S., Regenberg A., Rabins P.V. Psychiatric and neuropsychiatric adverse events associated with deep brain stimulation: a meta-analysis of ten years' experience. Mov. Disord. 2007, 22:1722-1728.
    • (2007) Mov. Disord. , vol.22 , pp. 1722-1728
    • Appleby, B.S.1    Duggan, P.S.2    Regenberg, A.3    Rabins, P.V.4
  • 3
    • 0017296144 scopus 로고
    • "Serotonin depression"-a biochemical subgroup within the affective disorders?
    • Asberg M., Thoren P., Traskman L., Bertilsson L., Ringberger V. "Serotonin depression"-a biochemical subgroup within the affective disorders?. Science 1976, 191:478-480.
    • (1976) Science , vol.191 , pp. 478-480
    • Asberg, M.1    Thoren, P.2    Traskman, L.3    Bertilsson, L.4    Ringberger, V.5
  • 6
    • 34447627504 scopus 로고    scopus 로고
    • Dopamine released from 5-HT terminals is the cause of l-DOPA-induced dyskinesia in parkinsonian rats
    • Carta M., Carlsson T., Kirik D., Bjorklund A. Dopamine released from 5-HT terminals is the cause of l-DOPA-induced dyskinesia in parkinsonian rats. Brain 2007, 130:1819-1833.
    • (2007) Brain , vol.130 , pp. 1819-1833
    • Carta, M.1    Carlsson, T.2    Kirik, D.3    Bjorklund, A.4
  • 7
    • 2442496420 scopus 로고    scopus 로고
    • Premature responding following bilateral stimulation of the rat subthalamic nucleus is amplitude and frequency dependent
    • Desbonnet L., Temel Y., Visser-Vandewalle V., Blokland A., Hornikx V., Steinbusch H.W. Premature responding following bilateral stimulation of the rat subthalamic nucleus is amplitude and frequency dependent. Brain Res. 2004, 1008:198-204.
    • (2004) Brain Res. , vol.1008 , pp. 198-204
    • Desbonnet, L.1    Temel, Y.2    Visser-Vandewalle, V.3    Blokland, A.4    Hornikx, V.5    Steinbusch, H.W.6
  • 9
    • 0025332552 scopus 로고
    • In-vivo brain dialysis of neurotransmitters
    • Di Chiara G. In-vivo brain dialysis of neurotransmitters. Trends Pharmacol. Sci. 1990, 11:116-121.
    • (1990) Trends Pharmacol. Sci. , vol.11 , pp. 116-121
    • Di Chiara, G.1
  • 10
    • 20044373674 scopus 로고    scopus 로고
    • Only physical aspects of quality of life are significantly improved by bilateral subthalamic stimulation in Parkinson's disease
    • Drapier S., Raoul S., Drapier D., Leray E., Lallement F., Rivier I., Sauleau P., Lajat Y., Edan G., Verin M. Only physical aspects of quality of life are significantly improved by bilateral subthalamic stimulation in Parkinson's disease. J. Neurol. 2005, 252:583-588.
    • (2005) J. Neurol. , vol.252 , pp. 583-588
    • Drapier, S.1    Raoul, S.2    Drapier, D.3    Leray, E.4    Lallement, F.5    Rivier, I.6    Sauleau, P.7    Lajat, Y.8    Edan, G.9    Verin, M.10
  • 13
    • 0029160159 scopus 로고
    • Evidence for a repetitive (burst) firing pattern in a sub-population of 5-hydroxytryptamine neurons in the dorsal and median raphe nuclei of the rat
    • Hajos M., Gartside S.E., Villa A.E., Sharp T. Evidence for a repetitive (burst) firing pattern in a sub-population of 5-hydroxytryptamine neurons in the dorsal and median raphe nuclei of the rat. Neuroscience 1995, 69:189-197.
    • (1995) Neuroscience , vol.69 , pp. 189-197
    • Hajos, M.1    Gartside, S.E.2    Villa, A.E.3    Sharp, T.4
  • 15
    • 33749513198 scopus 로고    scopus 로고
    • The pharmacology of the neurochemical transmission in the midbrain raphe nuclei of the rat
    • Harsing L.G. The pharmacology of the neurochemical transmission in the midbrain raphe nuclei of the rat. Curr. Neuropharmacol. 2006, 4:313-339.
    • (2006) Curr. Neuropharmacol. , vol.4 , pp. 313-339
    • Harsing, L.G.1
  • 16
    • 79957983508 scopus 로고    scopus 로고
    • High-frequency stimulation of the subthalamic nucleus inhibits the firing of juxtacellular labelled 5-HT-containing neurones
    • Hartung H., Tan S.K., Steinbusch H.M., Temel Y., Sharp T. High-frequency stimulation of the subthalamic nucleus inhibits the firing of juxtacellular labelled 5-HT-containing neurones. Neuroscience 2011, 186:135-145.
    • (2011) Neuroscience , vol.186 , pp. 135-145
    • Hartung, H.1    Tan, S.K.2    Steinbusch, H.M.3    Temel, Y.4    Sharp, T.5
  • 17
    • 0021334306 scopus 로고
    • Chloral hydrate anesthesia alters the responsiveness of central serotonergic neurons in the cat
    • Heym J., Steinfels G.F., Jacobs B.L. Chloral hydrate anesthesia alters the responsiveness of central serotonergic neurons in the cat. Brain Res. 1984, 291:63-72.
    • (1984) Brain Res. , vol.291 , pp. 63-72
    • Heym, J.1    Steinfels, G.F.2    Jacobs, B.L.3
  • 18
    • 0023796630 scopus 로고
    • Endogenous release of neuronal serotonin and 5-hydroxyindoleacetic acid in the caudate-putamen of the rat as revealed by intracerebral dialysis coupled to high-performance liquid chromatography with fluorimetric detection
    • Kalen P., Strecker R.E., Rosengren E., Bjorklund A. Endogenous release of neuronal serotonin and 5-hydroxyindoleacetic acid in the caudate-putamen of the rat as revealed by intracerebral dialysis coupled to high-performance liquid chromatography with fluorimetric detection. J. Neurochem. 1988, 51:1422-1435.
    • (1988) J. Neurochem. , vol.51 , pp. 1422-1435
    • Kalen, P.1    Strecker, R.E.2    Rosengren, E.3    Bjorklund, A.4
  • 21
    • 0033546666 scopus 로고    scopus 로고
    • Comparative effects of unilateral and bilateral subthalamic nucleus deep brain stimulation
    • Kumar R., Lozano A.M., Sime E., Halket E., Lang A.E. Comparative effects of unilateral and bilateral subthalamic nucleus deep brain stimulation. Neurology 1999, 53:561-566.
    • (1999) Neurology , vol.53 , pp. 561-566
    • Kumar, R.1    Lozano, A.M.2    Sime, E.3    Halket, E.4    Lang, A.E.5
  • 22
    • 34548672558 scopus 로고    scopus 로고
    • High-frequency stimulation of the subthalamic nucleus prolongs the increase in striatal dopamine induced by acute l-3,4-dihydroxyphenylalanine in dopaminergic denervated rats
    • Lacombe E., Carcenac C., Boulet S., Feuerstein C., Bertrand A., Poupard A., Savasta M. High-frequency stimulation of the subthalamic nucleus prolongs the increase in striatal dopamine induced by acute l-3,4-dihydroxyphenylalanine in dopaminergic denervated rats. Eur. J. Neurosci. 2007, 26:1670-1680.
    • (2007) Eur. J. Neurosci. , vol.26 , pp. 1670-1680
    • Lacombe, E.1    Carcenac, C.2    Boulet, S.3    Feuerstein, C.4    Bertrand, A.5    Poupard, A.6    Savasta, M.7
  • 23
    • 70349269138 scopus 로고    scopus 로고
    • The electrocorticogram signal can be modulated with deep brain stimulation of the subthalamic nucleus in the hemiparkinsonian rat
    • Lehmkuhle M.J., Bhangoo S.S., Kipke D.R. The electrocorticogram signal can be modulated with deep brain stimulation of the subthalamic nucleus in the hemiparkinsonian rat. J. Neurophysiol. 2009, 102:1811-1820.
    • (2009) J. Neurophysiol. , vol.102 , pp. 1811-1820
    • Lehmkuhle, M.J.1    Bhangoo, S.S.2    Kipke, D.R.3
  • 24
    • 77952089005 scopus 로고    scopus 로고
    • High-frequency stimulation of the subthalamic nucleus restores neural and behavioral functions during reaction time task in a rat model of Parkinson's disease
    • Li X.H., Wang J.Y., Gao G., Chang J.Y., Woodward D.J., Luo F. High-frequency stimulation of the subthalamic nucleus restores neural and behavioral functions during reaction time task in a rat model of Parkinson's disease. J. Neurosci. Res. 2010, 88:1510-1521.
    • (2010) J. Neurosci. Res. , vol.88 , pp. 1510-1521
    • Li, X.H.1    Wang, J.Y.2    Gao, G.3    Chang, J.Y.4    Woodward, D.J.5    Luo, F.6
  • 25
    • 25444515997 scopus 로고    scopus 로고
    • Long-term benefits in quality of life provided by bilateral subthalamic stimulation in patients with Parkinson disease
    • Lyons K.E., Pahwa R. Long-term benefits in quality of life provided by bilateral subthalamic stimulation in patients with Parkinson disease. J. Neurosurg. 2005, 103:252-255.
    • (2005) J. Neurosurg. , vol.103 , pp. 252-255
    • Lyons, K.E.1    Pahwa, R.2
  • 26
    • 0029095733 scopus 로고
    • Release of cerebral 5-hydroxytryptamine evoked by electrical stimulation of the dorsal and median raphe nuclei: effect of a neurotoxic amphetamine
    • McQuade R., Sharp T. Release of cerebral 5-hydroxytryptamine evoked by electrical stimulation of the dorsal and median raphe nuclei: effect of a neurotoxic amphetamine. Neuroscience 1995, 68:1079-1088.
    • (1995) Neuroscience , vol.68 , pp. 1079-1088
    • McQuade, R.1    Sharp, T.2
  • 27
    • 34247137134 scopus 로고    scopus 로고
    • Imaging the serotonin transporter during major depressive disorder and antidepressant treatment
    • Meyer J.H. Imaging the serotonin transporter during major depressive disorder and antidepressant treatment. J. Psychiatry Neurosci. 2007, 32:86-102.
    • (2007) J. Psychiatry Neurosci. , vol.32 , pp. 86-102
    • Meyer, J.H.1
  • 29
    • 10044278067 scopus 로고    scopus 로고
    • Brain serotonin transporter binding potential measured with carbon 11-labeled DASB positron emission tomography: effects of major depressive episodes and severity of dysfunctional attitudes
    • Meyer J.H., Houle S., Sagrati S., Carella A., Hussey D.F., Ginovart N., Goulding V., Kennedy J., Wilson A.A. Brain serotonin transporter binding potential measured with carbon 11-labeled DASB positron emission tomography: effects of major depressive episodes and severity of dysfunctional attitudes. Arch. Gen. Psychiatry 2004, 61:1271-1279.
    • (2004) Arch. Gen. Psychiatry , vol.61 , pp. 1271-1279
    • Meyer, J.H.1    Houle, S.2    Sagrati, S.3    Carella, A.4    Hussey, D.F.5    Ginovart, N.6    Goulding, V.7    Kennedy, J.8    Wilson, A.A.9
  • 30
    • 34547749076 scopus 로고    scopus 로고
    • The dorsal raphe nucleus-from silver stainings to a role in depression
    • Michelsen K.A., Schmitz C., Steinbusch H.W. The dorsal raphe nucleus-from silver stainings to a role in depression. Brain Res. Rev. 2007, 55:329-342.
    • (2007) Brain Res. Rev. , vol.55 , pp. 329-342
    • Michelsen, K.A.1    Schmitz, C.2    Steinbusch, H.W.3
  • 32
    • 76649108189 scopus 로고    scopus 로고
    • High-frequency stimulation of the subthalamic nucleus and l-3,4-dihydroxyphenylalanine inhibit in vivo serotonin release in the prefrontal cortex and hippocampus in a rat model of Parkinson's disease
    • Navailles S., Benazzouz A., Bioulac B., Gross C., De Deurwaerdere P. High-frequency stimulation of the subthalamic nucleus and l-3,4-dihydroxyphenylalanine inhibit in vivo serotonin release in the prefrontal cortex and hippocampus in a rat model of Parkinson's disease. J. Neurosci. 2010, 30:2356-2364.
    • (2010) J. Neurosci. , vol.30 , pp. 2356-2364
    • Navailles, S.1    Benazzouz, A.2    Bioulac, B.3    Gross, C.4    De Deurwaerdere, P.5
  • 33
    • 0021704673 scopus 로고
    • Organization of raphe-cortical projections in rat: a quantitative retrograde study
    • O'Hearn E., Molliver M.E. Organization of raphe-cortical projections in rat: a quantitative retrograde study. Brain Res. Bull. 1984, 13:709-726.
    • (1984) Brain Res. Bull. , vol.13 , pp. 709-726
    • O'Hearn, E.1    Molliver, M.E.2
  • 36
    • 0342618533 scopus 로고    scopus 로고
    • Forebrain afferents to the rat dorsal raphe nucleus demonstrated by retrograde and anterograde tracing methods
    • Peyron C., Petit J.M., Rampon C., Jouvet M., Luppi P.H. Forebrain afferents to the rat dorsal raphe nucleus demonstrated by retrograde and anterograde tracing methods. Neuroscience 1998, 82:443-468.
    • (1998) Neuroscience , vol.82 , pp. 443-468
    • Peyron, C.1    Petit, J.M.2    Rampon, C.3    Jouvet, M.4    Luppi, P.H.5
  • 37
    • 34548041194 scopus 로고    scopus 로고
    • Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease
    • Samii A., Kelly V.E., Slimp J.C., Shumway-Cook A., Goodkin R. Staged unilateral versus bilateral subthalamic nucleus stimulator implantation in Parkinson disease. Mov. Disord. 2007, 22:1476-1481.
    • (2007) Mov. Disord. , vol.22 , pp. 1476-1481
    • Samii, A.1    Kelly, V.E.2    Slimp, J.C.3    Shumway-Cook, A.4    Goodkin, R.5
  • 38
    • 0033875826 scopus 로고    scopus 로고
    • What contributes to quality of life in patients with Parkinson's disease?
    • Schrag A., Jahanshahi M., Quinn N. What contributes to quality of life in patients with Parkinson's disease?. J. Neurol. Neurosurg. Psychiatry 2000, 69:308-312.
    • (2000) J. Neurol. Neurosurg. Psychiatry , vol.69 , pp. 308-312
    • Schrag, A.1    Jahanshahi, M.2    Quinn, N.3
  • 39
    • 0024409941 scopus 로고
    • In vivo measurement of extracellular 5-hydroxytryptamine in hippocampus of the anaesthetized rat using microdialysis: changes in relation to 5-hydroxytryptaminergic neuronal activity
    • Sharp T., Bramwell S.R., Clark D., Grahame-Smith D.G. In vivo measurement of extracellular 5-hydroxytryptamine in hippocampus of the anaesthetized rat using microdialysis: changes in relation to 5-hydroxytryptaminergic neuronal activity. J. Neurochem. 1989, 53:234-240.
    • (1989) J. Neurochem. , vol.53 , pp. 234-240
    • Sharp, T.1    Bramwell, S.R.2    Clark, D.3    Grahame-Smith, D.G.4
  • 40
    • 0242653809 scopus 로고    scopus 로고
    • Synaptic plasticity in rat subthalamic nucleus induced by high-frequency stimulation
    • Shen K.Z., Zhu Z.T., Munhall A., Johnson S.W. Synaptic plasticity in rat subthalamic nucleus induced by high-frequency stimulation. Synapse 2003, 50:314-319.
    • (2003) Synapse , vol.50 , pp. 314-319
    • Shen, K.Z.1    Zhu, Z.T.2    Munhall, A.3    Johnson, S.W.4
  • 42
    • 0030611068 scopus 로고    scopus 로고
    • Relapse of depression after rapid depletion of tryptophan
    • Smith K.A., Fairburn C.G., Cowen P.J. Relapse of depression after rapid depletion of tryptophan. Lancet 1997, 349:915-919.
    • (1997) Lancet , vol.349 , pp. 915-919
    • Smith, K.A.1    Fairburn, C.G.2    Cowen, P.J.3
  • 43
    • 0009637974 scopus 로고    scopus 로고
    • Brain mechanisms associated with depressive relapse and associated cognitive impairment following acute tryptophan depletion
    • Smith K.A., Morris J.S., Friston K.J., Cowen P.J., Dolan R.J. Brain mechanisms associated with depressive relapse and associated cognitive impairment following acute tryptophan depletion. Br. J. Psychiatry 1999, 174:525-529.
    • (1999) Br. J. Psychiatry , vol.174 , pp. 525-529
    • Smith, K.A.1    Morris, J.S.2    Friston, K.J.3    Cowen, P.J.4    Dolan, R.J.5
  • 44
    • 0019464864 scopus 로고
    • Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals
    • Steinbusch H.W. Distribution of serotonin-immunoreactivity in the central nervous system of the rat-cell bodies and terminals. Neuroscience 1981, 6:557-618.
    • (1981) Neuroscience , vol.6 , pp. 557-618
    • Steinbusch, H.W.1
  • 45
    • 21344471919 scopus 로고    scopus 로고
    • Effect of subthalamic stimulation on mood state in Parkinson's disease: evaluation of previous facts and problems
    • discussion 187
    • Takeshita S., Kurisu K., Trop L., Arita K., Akimitsu T., Verhoeff N.P. Effect of subthalamic stimulation on mood state in Parkinson's disease: evaluation of previous facts and problems. Neurosurg. Rev. 2005, 28:179-186. discussion 187.
    • (2005) Neurosurg. Rev. , vol.28 , pp. 179-186
    • Takeshita, S.1    Kurisu, K.2    Trop, L.3    Arita, K.4    Akimitsu, T.5    Verhoeff, N.P.6
  • 47
    • 33750694210 scopus 로고    scopus 로고
    • Early onset of selective serotonin reuptake inhibitor antidepressant action: systematic review and meta-analysis
    • Taylor M.J., Freemantle N., Geddes J.R., Bhagwagar Z. Early onset of selective serotonin reuptake inhibitor antidepressant action: systematic review and meta-analysis. Arch. Gen. Psychiatry 2006, 63:1217-1223.
    • (2006) Arch. Gen. Psychiatry , vol.63 , pp. 1217-1223
    • Taylor, M.J.1    Freemantle, N.2    Geddes, J.R.3    Bhagwagar, Z.4
  • 49
    • 33744540496 scopus 로고    scopus 로고
    • Behavioural changes after bilateral subthalamic stimulation in advanced Parkinson disease: a systematic review
    • Temel Y., Kessels A., Tan S., Topdag A., Boon P., Visser-Vandewalle V. Behavioural changes after bilateral subthalamic stimulation in advanced Parkinson disease: a systematic review. Parkinsonism Relat. Disord. 2006, 12:265-272.
    • (2006) Parkinsonism Relat. Disord. , vol.12 , pp. 265-272
    • Temel, Y.1    Kessels, A.2    Tan, S.3    Topdag, A.4    Boon, P.5    Visser-Vandewalle, V.6
  • 56
    • 0842320980 scopus 로고    scopus 로고
    • Effect of motor improvement on quality of life following subthalamic stimulation is mediated by changes in depressive symptomatology
    • Troster A.I., Fields J.A., Wilkinson S., Pahwa R., Koller W.C., Lyons K.E. Effect of motor improvement on quality of life following subthalamic stimulation is mediated by changes in depressive symptomatology. Stereotact. Funct. Neurosurg. 2003, 80:43-47.
    • (2003) Stereotact. Funct. Neurosurg. , vol.80 , pp. 43-47
    • Troster, A.I.1    Fields, J.A.2    Wilkinson, S.3    Pahwa, R.4    Koller, W.C.5    Lyons, K.E.6
  • 57
    • 0018775017 scopus 로고
    • The organization of the thalamic, nigral and raphe cells projecting to the medial vs lateral caudate-putamen in rat. A fluorescent retrograde double labeling study
    • van der Kooy D. The organization of the thalamic, nigral and raphe cells projecting to the medial vs lateral caudate-putamen in rat. A fluorescent retrograde double labeling study. Brain Res. 1979, 169:381-387.
    • (1979) Brain Res. , vol.169 , pp. 381-387
    • van der Kooy, D.1
  • 58
    • 0018632621 scopus 로고
    • Central serotonin metabolism and frequency of depression
    • van Praag H.M., de Haan S. Central serotonin metabolism and frequency of depression. Psychiatry Res. 1979, 1:219-224.
    • (1979) Psychiatry Res. , vol.1 , pp. 219-224
    • van Praag, H.M.1    de Haan, S.2
  • 60
    • 34548678185 scopus 로고    scopus 로고
    • High frequency stimulation of the subthalamic nucleus improves speed of locomotion but impairs forelimb movement in Parkinsonian rats
    • Vlamings R., Visser-Vandewalle V., Koopmans G., Joosten E.A., Kozan R., Kaplan S., Steinbusch H.W., Temel Y. High frequency stimulation of the subthalamic nucleus improves speed of locomotion but impairs forelimb movement in Parkinsonian rats. Neuroscience 2007, 148:815-823.
    • (2007) Neuroscience , vol.148 , pp. 815-823
    • Vlamings, R.1    Visser-Vandewalle, V.2    Koopmans, G.3    Joosten, E.A.4    Kozan, R.5    Kaplan, S.6    Steinbusch, H.W.7    Temel, Y.8
  • 61
    • 69049104020 scopus 로고    scopus 로고
    • Bilateral high frequency stimulation of the subthalamic nucleus normalizes COX activity in the substantia nigra of Parkinsonian rats
    • Vlamings R., Visser-Vandewalle V., Kozan R., Kaplan S., Steinbusch H.W., Temel Y. Bilateral high frequency stimulation of the subthalamic nucleus normalizes COX activity in the substantia nigra of Parkinsonian rats. Brain Res. 2009, 1288:143-148.
    • (2009) Brain Res. , vol.1288 , pp. 143-148
    • Vlamings, R.1    Visser-Vandewalle, V.2    Kozan, R.3    Kaplan, S.4    Steinbusch, H.W.5    Temel, Y.6
  • 63
    • 79954563661 scopus 로고    scopus 로고
    • Serotonin innervation of human basal ganglia
    • Wallman M.J., Gagnon D., Parent M. Serotonin innervation of human basal ganglia. Eur. J. Neurosci. 2011, 33:1519-1532.
    • (2011) Eur. J. Neurosci. , vol.33 , pp. 1519-1532
    • Wallman, M.J.1    Gagnon, D.2    Parent, M.3
  • 65
    • 77952320903 scopus 로고    scopus 로고
    • Deep brain stimulation plus best medical therapy versus best medical therapy alone for advanced Parkinson's disease (PD SURG trial): a randomised, open-label trial
    • Williams A., Gill S., Varma T., Jenkinson C., Quinn N., Mitchell R., Scott R., Ives N., Rick C., Daniels J., Patel S., Wheatley K. Deep brain stimulation plus best medical therapy versus best medical therapy alone for advanced Parkinson's disease (PD SURG trial): a randomised, open-label trial. Lancet Neurol. 2010, 9:581-591.
    • (2010) Lancet Neurol. , vol.9 , pp. 581-591
    • Williams, A.1    Gill, S.2    Varma, T.3    Jenkinson, C.4    Quinn, N.5    Mitchell, R.6    Scott, R.7    Ives, N.8    Rick, C.9    Daniels, J.10    Patel, S.11    Wheatley, K.12


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.