Late-phase contrast-enhanced ultrasound reflects biological features of instability in human carotid atherosclerosis

Stroke

Volumn 42, Issue 12, 2011, Pages 3634-3636

  Shalhoub, Joseph ^a,b   Monaco, Claudia ^b   Owen, David R J ^b   Gauthier, Thomas ^b   Thapar, Ankur ^a   Leen, Edward L S ^b   Davies, Alun H ^a  

^a CHARING CROSS HOSPITAL   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Angiogenesis; Atherosclerosis; Inflammation; Late phase contrast enhanced ultrasound; Stroke

Indexed keywords

CD31 ANTIGEN; CD68 ANTIGEN; INTERLEUKIN 6; INTERSTITIAL COLLAGENASE; STROMELYSIN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; CAROTID ATHEROSCLEROSIS; CAROTID ENDARTERECTOMY; CELL CULTURE; CLINICAL ARTICLE; ECHOGRAPHY; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; LATE PHASE CONTRAST ENHANCED ULTRASOUND; MACROPHAGE; MALE; MICROBUBBLE; PRIORITY JOURNAL;

AGED; ATHEROSCLEROSIS; CAROTID ARTERIES; CAROTID ARTERY DISEASES; CAROTID STENOSIS; ENDARTERECTOMY, CAROTID; FEMALE; HUMANS; INFLAMMATION; MALE; MICROBUBBLES;

EID: 84856225983     PISSN: 00392499     EISSN: 15244628     Source Type: Journal    
DOI: 10.1161/STROKEAHA.111.631200     Document Type: Article

References (6)

1. Narula J, Strauss HW. The popcorn plaques. Nat Med. 2007;13:532-534. (Pubitemid 46828471)
2. Staub D, Patel MB, Tibrewala A, Ludden D, Johnson M, Espinosa P, et al. Vasa vasorum and plaque neovascularization on contrast-enhanced carotid ultrasound imaging correlates with cardiovascular disease and past cardiovascular events. Stroke. 2010;41:41-47.
3. Owen DR, Shalhoub J, Miller S, Gauthier T, Doryforou O, Davies AH, et al. Inflammation within carotid atherosclerotic plaque: Assessment with late-phase contrast-enhanced us. Radiology. 2010;255:638-644.
4. Monaco C, Andreakos E, Kiriakidis S, Mauri C, Bicknell C, Foxwell B, et al. Canonical pathway of nuclear factor kappa B activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis. Proc Natl Acad Sci U S A. 2004;101:5634-5639. (Pubitemid 38481208)
5. Lindner JR, Dayton PA, Coggins MP, Ley K, Song J, Ferrara K, et al. Noninvasive imaging of inflammation by ultrasound detection of phagocytosed microbubbles. Circulation. 2000;102:531-538. (Pubitemid 30639971)
6. Tsutsui JM, Xie F, Cano M, Chomas J, Phillips P, Radio SJ, et al. Detection of retained microbubbles in carotid arteries with real-time low mechanical index imaging in the setting of endothelial dysfunction. J Am Coll Cardiol. 2004;44:1036-1046. (Pubitemid 39165139)