Connexin 32 is involved in mitosis

GLIA

Volumn 60, Issue 3, 2012, Pages 457-464

  Mones, Saleh ^a   Bordignon, Benoit ^a   Fontes, Michel ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Connexin 32; Peripheral neuropathy; Schwann cell differentiation

Indexed keywords

CONNEXIN 32; GJB1 PROTEIN; PROTEIN; RNA; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; GENE DOSAGE; GENE MUTATION; HEREDITARY MOTOR SENSORY NEUROPATHY; HUMAN; MALE; MITOSIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ANIMALS; CELL NUCLEUS; CELLS, CULTURED; CENTROSOME; CONNEXINS; EMBRYO, MAMMALIAN; FIBROBLASTS; GENE DOSAGE; HUMANS; LOCOMOTION; MICE; MICE, TRANSGENIC; MITOSIS; MUTATION; ROTAROD PERFORMANCE TEST;

EID: 84856222495     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22279     Document Type: Article

References (32)

1. Abrams CK, Freidin MM, Verselis VK, Bennett MV, Bargiello TA. 2001. Functional alterations in gap junction channels formed by mutant forms of connexin 32: evidence for loss of function as a pathogenic mechanism in the X-linked form of Charcot-Marie-Tooth disease. Brain Res 900: 9-25.
2. Anzini P, Neuberg DH-H, Schachner M, Nelles E, Willecke K, Zielasek J, Toyka K, Suter U, Martini R. 1997. Structural abnormalities and deficient maintenance of peripheral nerve myelin in mice lacking the gap junction protein connexin32. J Neurosci 17: 4545-4561.
3. Atanasoski S, Scherer SS, Nave KA, Suter U. 2000. Proliferation of Schwann cells and regulation of cyclin D1 expression in an animal model of Charcot-Marie-Tooth disease type 1A. J Neurosci Res 67: 443-449.
4. Bennett MV, Barrio LC, Bargiello TA, Spray DC, Hertzberg E, Sáez JC. 1991. Gap junctions: new tools, new answers, new questions. Neuron 6: 305-320.
5. Bergoffen J, Scherer SS, Wang S, Scott MO, Bone LJ, Paul DL, Chen K, Lensch MW, Chance PF, Fischbeck KH. 1993. Connexin mutations in X-linked Charcot-Marie-Tooth disease. Science 262: 2039-2042.
6. Bicego M, Morassutto S, Hernandez VH, Morgutti M, Mammano F, D'Andrea P, Bruzzone R. 2006. Selective defects in channel permeability associated with Cx32 mutations causing X-linked Charcot-Marie-Tooth disease. Neurobiol Dis 21: 607-617.
7. Boerkel CF, Takashima H, Garcia CA, Olney RK, Johnson J, Berry K, et al. 2002. Charcot-Marie-Tooth disease and related neuropathies: Mutation distribution and genotype-phenotype correlation. Ann Neurol 51: 190-201.
8. Burtey S, Riera M, Ribe E, Pennenkamp P, Rance R, Luciani J, Dworniczak B, Mattei MG, Fontés M. 2008. Centrosome overduplication and mitotic instability in PKD2 transgenic lines. Cell Biol Int 32: 1193-1198.
9. De Jonghe P, Nelis E, Timmerman V, Löfgren A, Martin JJ, Van Broeckhoven C. 1999. Molecular diagnostic testing in Charcot-Marie-Tooth disease and related disorders. Approaches and results. Ann NY Acad Sci 883: 389-396.
10. Deschênes SM, Walcott JL, Wexler TL, Scherer SS, Fischbeck KH. 1997. Altered trafficking of mutant connexin32. J Neurosci 17: 9077-9084.
11. Dunham NW, Miya TS. 1957. A note on a simple apparatus for detecting neurological deficit in rats and mice. J Am Pharma Assoc 46: 208-209.
12. Dyck, P.J. and E.H. Lambert. 1968. Lower motor and primary sensory neuron diseases with peroneal muscular atrophy. I. Neurologic, genetic, and electrophysiologic findings in hereditary polyneuropathies. Arch Neurol 18: 603-618.
13. Gonzaga-Jauregui C, Zhang F, Towne CF, Batish SD, Lupski JR. 2010. GJB1/Connexin 32 whole gene deletions in patients with X-linked Charcot-Marie-Tooth disease. Neurogenetics 11: 465-470.
14. Hutchins JR, Toyoda Y, Hegemann B, Poser I, Hériché JK, Sykora MM, Augsburg M, Hudecz O, Buschhorn BA, Bulkescher J, Conrad C, Comartin D, Schleiffer A, Sarov M, Pozniakovsky A, Slabicki MM, Schloissnig S, Steinmacher I, Leuschner M, Ssykor A, Lawo S, Pelletier L, Stark H, Nasmyth K, Ellenberg J, Durbin R, Buchholz F, Mechtler K, Hyman AA, Peters JM. 2010. Systematic analysis of human protein complexes identifies chromosome segregating proteins. Science 328: 593-599.
15. Huxley C, Passage E, Manson A, Putzu G, Figarella-Branger D, Pellissier JF, Fontes M. 1996. Construction of a mouse model of Charcot-Marie-Tooth disease type 1A by pronuclear injection of human YAC DNA. Human Molecular Genetics 5: 563-569.
16. Ionasescu V, Ionasescu R, Searby C. 1996. Correlation between connexin 32 gene mutations and clinical phenotype in X-linked dominant Charcot-Marie-Tooth neuropathy. Am J Med Genet 63: 486-491.
17. Kumar NM, Gilula NB. 1992. Molecular biology and genetics of gap junction channels. Semin Cell Biol 3: 3-16.
18. Liu F, Arce FT, Ramachandran S, Lal R. 2006. Nanomechanics of hemichannel conformations: Connexin flexibility underlying channel opening and closing. J Biol Chem 281: 23207-23217.
19. Martyn CN, Hughes RA. 1997. Epidemiology of peripheral neuropathy. J Neurol Neurosurg Psychiatry 62: 310-318.
20. Matsumoto Y, Maller JL. 2002. Calcium, calmodulin, and CaMKII requirement for initiation of centrosome duplication in Xenopus egg extracts. Science 295: 499-502.
21. Mese G, Richard G, White TW. 2007. Gap junctions: Basic structure and function. J Invest Dermatol 127: 2516-2524.
22. Neumann B, Walter T, Hériché JK, Bulkescher J, Erfle H, Conrad C, Rogers P, Poser I, Held M, Liebel U, Cetin C, Sieckmann F, Pau G, Kabbe R, Wünsche A, Satagopam V, Schmitz MH, Chapuis C, Gerlich DW, Schneider R, Eils R, Huber W, Peters JM, Hyman AA, Durbin R, Pepperkok R, Ellenberg J. 2010. Phenotypic profiling of the human genome by time-lapse microscopy reveals cell division genes. Nature 464: 721-727.
23. Norreel JC, Jamon M, Riviere G, Passage E, Fontés M, Clarac F. 2001. Behavioural profiling of a murine Charcot-Marie-Tooth type 1A model. Eur J Neurosci 8: 1625-1634.
24. Oh S, Ri Y, Bennett MV, Trexler EB, Verselis VK, Bargiello TA. 1997. Changes in permeability caused by connexin 32 mutations underlie X-linked Charcot-Marie-Tooth disease. Neuron 19: 927-938.
25. Sancho S, Young P, Suter U. 2001. Regulation of Schwann cell proliferation and apoptosis in PMP22-deficient mice and mouse models of Charcot-Marie-Tooth disease type 1A. Brain 124: 2177-2187.
26. Scherer SS, Deschênes SM, Xu YT, Grinspan JB, Fischbeck KH, Paul DL. 1995. Connexin32 is a myelin-related protein in the PNS and CNS. J Neurosci 15: 8281-8194.
27. Scherer SS, Xu YT, Messing A, Willecke K, Fischbeck KH, Jeng LJ. 2005. Transgenic expression of human connexin32 in myelinating Schwann cells prevents demyelination in connexin32-null mice. J Neurosci 25: 1550-1559.
28. Scherer SS, Xu YT, Nelles E, Fischbeck K, Willecke K, Bone LJ. 1998. Connexin32-null mice develop demyelinating peripheral neuropathy. Glia 24: 8-20.
29. Wang HL, Chang WT, Yeh TH, Wu T, Chen MS, Wu CY. 2004. Functional analysis of connexin-32 mutants associated with X-linked dominant Charcot-Marie-Tooth disease. Neurobiol Dis 15: 361-370.
30. Warming S, Costantino N, Court DL, Jenkins NA, Copeland NG. 2005. Simple and highly efficient BAC recombineering using galK selection. Nucleic Acids Res 33: e36.
31. Yoshimura T, Ohnishi A, Yamamoto T, Fukushima Y, Kitani M, Kobayashi T. 1996. Two novel mutations (C53S, S26L) in the connexin32 of Charcot-Marie-Tooth disease type X families. Hum Mutat 8: 270-272.
32. Yum SW, Kleopa KA, Shumas S, Scherer SS. 2002. Diverse trafficking abnormalities of connexin32 mutants causing CMTX. Neurobiol Dis 11: 43-52.