Two-photon confocal imaging study: Cell uptake of two photon dyes-labeled PAMAM dendrons in HeLa cells

Journal of Biomedical Materials Research - Part A

Volumn 100 A, Issue 3, 2012, Pages 746-756

  Tsai, Hsieh Chih ^a   Imae, Toyoko ^a   Calderõ, Gabriela ^b   Solans, Conxita ^b  

^a NATIONAL TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^b BIOMATERIALES Y NANOMEDICINA CIBER BBN   (Spain)

Author keywords

cell membrane interaction; macromolecular probe; PAMAM dendron; two photo confocal microscopy

Indexed keywords

BIOLOGICAL IMAGE ANALYSIS; CELL AFFINITY; CELL UPTAKE; CONFOCAL IMAGING; DENDRONS; DUAL IMAGING; ENDOCYTOSIS PATHWAY; ENDOCYTOTIC PATHWAY; FLUORESCENCE SPECTRA; HELA CELL; IN-SITU; LACTATE DEHYDROGENASE ASSAYS; LIVING HELA CELLS; MEMBRANE DAMAGE; MEMBRANE INTEGRITY; MULTIVALENCY; NEAR INFRARED REGION; NEAR-INFRARED LASERS; ONE-PHOTON EXCITATION; OPTICAL IMAGING; TWO PHOTON; TWO-PHOTON EXCITATIONS;

CELL MEMBRANES; CONFOCAL MICROSCOPY; DENDRIMERS; DERIVATIVES; INFRARED DEVICES; INFRARED LASERS; LASER EXCITATION; MEMBRANES; MOLECULAR BIOLOGY; PHOTONS;

CYTOLOGY;

LACTATE DEHYDROGENASE; POLYAMIDOAMINE;

AFFINITY LABELING; ARTICLE; BINDING AFFINITY; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DENDRITE; ENDOCYTOSIS; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; MULTIPHOTON MICROSCOPY; ULTRAVIOLET IRRADIATION;

BIOCOMPATIBLE MATERIALS; DENDRIMERS; FLUORESCENT DYES; HELA CELLS; HUMANS; MATERIALS TESTING; MICROSCOPY, CONFOCAL; MOLECULAR STRUCTURE; PHOTONS;

EID: 84856217716     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.33283     Document Type: Article

References (42)

1. Chow YL, Johansson CI, Zhang YH, Gautron R, Yang L, Rassat A, Yang SZ,. Spectroscopic and electrochemical properties of 1,3-diketonatoboron derivatives. J Phys Org Chem 1996; 9: 7-16. (Pubitemid 126677688)
2. Zhang G, Chen J, Payne SJ, Kooi ST, Demas JN, Fraser CL,. Multi-emissive difluoroboron dibenzoylmethane polylactide exhibiting intense fluorescence and oxygen-sensitive room temperature phosphorescence. J Am Chem Soc 2007; 129: 8942-8943. (Pubitemid 47171825)
3. Loudet A, Burgess K,. BODIPY dyes and their derivatives: Syntheses and spectroscopic properties. Chem Rev 2007; 107: 4891-4832.
4. Zheng Q, He GS, Prasad PN,. A novel near IR two-photon absorbing chromophore: Optical limiting and stabilization performances at an optical communication wavelength. Chem Phys Lett 2009; 475: 250-255.
5. Voit B,. New developments in hyperbranched polymers. J Polym Sci Part A: Polym Chem 2000; 38: 2505-2525.
6. Lee CC, Mackay AJ, Frechet JMJ, Szoka FC,. Designing dendrimer for biological application. Nat Biotechnol 2005; 23: 1517-1526.
7. Al-Jamal KT, Ramaswamy C, Florence AT,. Supramolecular structure from dendrons and dendrimers. Adv Drug Delivery Rev 2005; 57: 2238-2270
8. Amir JR, Pessah N, Shamis M, Shabat D,. Self-immolative dendrimers. Angew Chem Int Ed 2003; 42: 4494-4499. (Pubitemid 37214522)
9. Shum P, Kim JM, Thompson DH,. Phototriggering of liposomal drug delivery systems. Adv Drug Delivery Rev 2001; 53: 273-284. (Pubitemid 34024910)
10. Szalai ML, Kevwitch RM, McGrath DV,. Geometric disassembly of dendrimers: Dendritic amplification. J Am Chem Soc 2003; 125: 15688-15689. (Pubitemid 37553655)
11. de-Groot FMH, Albrecht C, Koekkoek R, Beusker HP, Scheeren HW,. Cascade-release dendrimers liberate all end groups upon a single triggering event in the dendritic core. Angew Chem Int Ed 2003; 42: 4490-4494. (Pubitemid 37214521)
12. Parimi S, Timothy BJ, Callen FD, Prestidge CA,. Mechanistic insight into cell growth, internalization and cytotoxicity of PAMAM dendrimers. Biomacromolecules 2010; 11: 382-389.
13. Zhang YZ, Smith BD,. High-generation polycationic dendrimers are unusually effective at disrupting anionic vesicles: Membrane bending model. Bioconjug Chem 2000; 11: 805-814.
14. Uppuluri S, Piehler L, Li J, Hagnauer LG, Tomalia DA,. Core-shell Tecto(dendrimers): Synthesis and characterization of saturated shell models. Adv Mater 2000; 12: 796-800.
15. Mecke A, Uppuluri S, Sassanella TM, Lee DK, Ramamoorthy A, Baker JR, Orr GB, Banaszak MM,. Holl. direct observation of lipid bilayer disruption by poly(amidoamine) dendrimers. Chem Phys Lipids 2004; 132: 3-14. (Pubitemid 39458316)
16. Leroueil RP, Berry AS, Duthie K, Han G, Rotello MV, McNerny QD, Baker R, Orr G, Holl B,. Wide varieties of cationic nanoparticles induce defects in supported lipid bilayers. Nano Lett 2008; 8: 420-424 (Pubitemid 351345993)
17. Hong S, Bielinska U, Mecke A, Keszler B, Beals L, Shi X, Balogh L, Orr GB, Baker RJ, Banaszak MM, Holl B,. Interaction of poly(amidoamine) dendrimers with supported lipid bilayers and cells: Hole formation and the relation to transport. Bioconjug Chem 2004; 15: 774-782. (Pubitemid 38981951)
18. Hong S, Leroueil RP, Janus KE, Peters LJ, Kober MM, Islam TM, Orr GB, Baker RJ, Holl MMB,. Interaction of polycationic polymers with supported lipid bilayers and cells: Nanoscale hole formation and enhanced membrane permeability. Bioconjug Chem 2006; 17: 728-734. (Pubitemid 43794383)
19. Mullen GD, Fang M, Desai A, Baker JR, Orr GB, Holl MMB,. A quantitative assessment of nanoparticle ligand distributions: Implications for targeted drug and imaging delivery in dendrimer conjugates. ACS Nano 2010; 4: 657-670.
20. Koley D, Bard AJ,. Triton X-100 concentration effects on membrane permeability of single HeLa cells by scanning electrochemical microscopy (SECM). Proc Natl Acad Sci USA 107: 16783-13787.
21. Hunter AC, Sander JKM,. The nature of pi-pi interaction. J Am Chem Soc 1990; 112: 5525-5534.
22. Wiwattanapatapee R, Carreno-Gomez B, Malik N, Duncan R,. Anionic PAMAM dendrimers rapidly cross adult rat intestine in vitro: A potential oral delivery system? Pharm Res 2000; 17: 991-998.
23. Paulo RMP, Costa SMB,. Non-covalent dendrimer-porphyrin interactions: The intermediacy of H-aggregates. Photochem Photobiol Sci 2003; 2: 597-604. (Pubitemid 41646683)
24. Shcharbin D, Klajnert B, Mazhul V, Bryszewska M,. Dendrimer interactions with hydrophobic fluorescent probes and human serum albumin. J Fluorescence 2005; 15: 21-28. (Pubitemid 40536202)
25. Karukstis KK, Perelman LA, Wong WK,. Spectroscopic characterization of azo dye aggregation on dendrimer surface. Langmuir 2002; 18: 10363-10371.
26. Kubat P, Lang K, Janda P, Anzenbacher P,. Interaction of porphyrins with a dendrimer template self-aggregation controlled by pH. Langmuir 2005; 21: 9714-9720. (Pubitemid 41507027)
27. Samoc M, Morrall PJ, Dalton TG, Marie PC, Humphery MG,. Two photon and three photon absorption in organometallic dendrimer. Angew Chem 2007; 46: 731-733. (Pubitemid 46155400)
28. Gennuso F, Fernetti C, Tirolo C, Testa N, L'Episcopo F, Caniglia S, Morale CM, Ostrow DJ, Pascolo L, Tiribelli C, Marchetti B,. Bilirubin protects astrocytes from its own toxicity by inducing up-regulation and translocation of multidrug resistance-associated protein 1 (mrp1). Proc Natl Acad Sci USA 2004; 101: 2470-2475. (Pubitemid 38269335)
29. Rajagopal A, Pant C, Simon M, Chen Y,. In vivo analysis of human multidrug resistance protein (MRP1) activity using transient expression of fluorescently Tagged MRP1. Cancer Res 2002; 62: 391-396. (Pubitemid 34106410)
30. Hipfner RD, Gauldie DS, Deeley GR, Cole SPC,. Detection of the Mr 190,000 multidrug resistance protein, MRP, with monoclonal antibodies. Cancer Res 1994; 54: 5788-5792.
31. Koley D, Bard AJ,. Triton X-100 concentration effects on membrane permeability of single HeLa cells by scanning electrochemical microscopy (SECM). Proc Natl Acad Sci USA 107: 16783-13787.
32. Murphy DJ,. The biogenesis and functions of lipid bodies in animals, plants and microorganisms. Prog Lipid Res 2001; 40: 325-438. (Pubitemid 32727212)
33. Manders MME, Verbeek JF, Aten JA,. Measurement of co-localization of objects in dual-color confocal images. J Microsc 1993; 169: 375-382. (Pubitemid 23119681)
34. Manders MME, Stap J, Brakenhoff JG, van Driel R, Aten JA,. Dynamics of three-dimensional replication patterns during the Sphase, analysed by double labelling of DNA and confocal microscopy. J Cell Sci 1992; 103: 857-862. (Pubitemid 23023255)
35. Dahlstedt E, Collins AH, Balaz M, Kuimova KM, Khurana M, Wilson CB, Phillips D, Anderson HL,. One- and two-photon activated phototoxicity of conjugated porphyrin dimers with high two-photon absorption cross sections. Org Biomol Chem 2009; 7: 897-904.
36. Starkey RJ, Rebane KA, Drobizhev AM, Meng F, Gong A, Elliott A, Mcinnerney K, Spangler CW,. New two photon activated photodynamic therapy sensitizers induce xenograft tumor regression after near ir laser treatment through the body if the host mouse. Clin Cancer Res 2008; 14: 6564-6573.
37. Saovapakhiran A, D'Emanuele A, Attwood D, Penny J,. Surface modification of PAMAM dendrimers modulates the mechanism of cellular internalization. Bioconjug Chem 2009; 20: 693-701.
38. Ottaviani FM, Daddi R, Brustolon M, Turro JN, Tomalia DA,. Structural modifications of DMPC vesicles upon Interaction with poly(amidoamine) dendrimers studied by CW-electron paramagnetic resonance and electron spin-echo techniques. Langmuir 1999; 15: 1973-1980.
39. Zhang YZ, Smith BD,. High-generation polycationic dendrimers are unusually effective at disrupting anionic vesicles: Membrane bending model. Bioconjug Chem 2000; 11: 805-814.
40. Karoonuthaisiri N, Titiyevskiy K, Thomas JL,. Destabilization of fatty acid-containing liposomes by. polyamidoamine dendrimers. Colloids Surf B 2003; 27: 365-375. (Pubitemid 36132183)
41. Sideratou Z, Foundis J, Tsiourvas D, Nezis PI, Papadimas G, Paleos CM,. A novel dendrimeric "glue" for adhesion of phosphatidyl choline-based liposomes. Langmuir 2002; 18: 5036-5039. (Pubitemid 35383476)
42. Mammen M, Choi KS, Whitesides GM,. Polyvalent interactions in biological systems: implications for design and use of multivalent ligands and inhibitors. Angew Chem Int Ed 1998; 37: 2754-2799.