Microthrombosis after experimental subarachnoid hemorrhage: Time course and effect of red blood cell-bound thrombin-activated pro-urokinase and clazosentan

Experimental Neurology

Volumn 233, Issue 1, 2012, Pages 357-363

  Pisapia, Jared M ^a   Xu, Xiangsheng ^a   Kelly, Jane ^a   Yeung, Jamie ^a   Carrion, Geneive ^a   Tong, Huaiyu ^b   Meghan, Sudha ^a   El Falaky, Omar M ^c   Grady, M Sean ^a   Smith, Douglas H ^a   Zaitsev, Sergei ^d   Muzykantov, Vladimir R ^d   Stiefel, Michael F ^e   Stein, Sherman C ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^b CHINESE PLA GENERAL HOSPITAL   (China)

^c CAIRO UNIVERSITY   (Egypt)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e WESTCHESTER MEDICAL CENTER   (United States)

Author keywords

Clazosentan; Experimental; Microclots; Microthrombi; Subarachnoid hemorrhage; Thromboembolism; Urokinase; Vasospasm

Indexed keywords

CLAZOSENTAN; EOSIN; HEMATOXYLIN; PROUROKINASE; THROMBIN; THROMBIN ANTITHROMBIN COMPLEX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BASAL GANGLION; BRAIN CORTEX; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DISEASE COURSE; DRUG BINDING; DRUG TARGETING; ERYTHROCYTE; HEMATOLOGICAL PARAMETERS; HIPPOCAMPUS; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; MALE; MICROCLOT BURDEN; MICROTHROMBUS; MONOTHERAPY; MORTALITY; MOUSE; NONHUMAN; OCCLUSIVE CEREBROVASCULAR DISEASE; PRIORITY JOURNAL; SUBARACHNOID HEMORRHAGE; THROMBOSIS PREVENTION; TIME;

ANALYSIS OF VARIANCE; ANIMALS; CEREBRAL ARTERIES; DIOXANES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DRUG DELIVERY SYSTEMS; ERYTHROCYTES; FIBRINOLYTIC AGENTS; GLYCOPHORIN; MALE; MICE; MICE, INBRED C57BL; PYRIDINES; PYRIMIDINES; SUBARACHNOID HEMORRHAGE; SULFONAMIDES; TETRAZOLES; THROMBOSIS; TIME FACTORS; UROKINASE-TYPE PLASMINOGEN ACTIVATOR;

EID: 84856212785     PISSN: 00144886     EISSN: 10902430     Source Type: Journal    
DOI: 10.1016/j.expneurol.2011.10.029     Document Type: Article

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