Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease
The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group
Fedorak R, Gangl A, Elson C, et al. Recombinant human interleukin 10 in the treatment of patients with mild to moderately active Crohn's disease. The Interleukin 10 Inflammatory Bowel Disease Cooperative Study Group. Gastroenterology. 2000;119:1473-82.
Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease
Crohns Disease IL-10 Cooperative Study Group
Schreiber S, Fedorak R, Nielsen O, et al. Safety and efficacy of recombinant human interleukin 10 in chronic active Crohn's disease. Crohns Disease IL-10 Cooperative Study Group. Gastroenterology. 2000;119:1461-72.
FK506 microparticles mitigate experimental colitis with minor renal calcineurin suppression
Lamprecht A, Yamamoto H, Ubrich N, Takeuchi H, Maincent P, Kawashima Y. FK506 microparticles mitigate experimental colitis with minor renal calcineurin suppression. Pharm Res. 2005;22:193-9.
Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats
Lamprecht A, Yamamoto H, Takeuchi H, Kawashima Y. Nanoparticles enhance therapeutic efficiency by selectively increased local drug dose in experimental colitis in rats. J Pharmacol Exp Ther. 2005;315:196-202.
Size-dependent bioadhesion of micro-and nanoparticulate carriers to the inflamed colonic mucosa
Lamprecht A, Schäfer U, Lehr CM. Size-dependent bioadhesion of micro-and nanoparticulate carriers to the inflamed colonic mucosa. Pharm Res. 2001;18:788-93.
Oral IL-10 gene delivery in a microsphere-based formulation for local transfection and therapeutic efficacy in inflammatory bowel disease
Bhavsar M, Amiji M. Oral IL-10 gene delivery in a microsphere-based formulation for local transfection and therapeutic efficacy in inflammatory bowel disease. Gene Ther. 2008;15:1200-9.