Myc target miRs and liver cancer: Small molecules to get Myc sick

Gastroenterology

Volumn 142, Issue 2, 2012, Pages 214-218

  Buendia, Marieannick ^a   Bourre, Ludovic ^b   Cairo, Stefano ^b  

^a HÔPITAL PAUL BROUSSE   (France)

^b Parc Scientifique de Luminy   (France)

Author keywords

basic helixloophelix leucine zipper; bHLHZ; HB; HCC; hepatoblastoma; hepatocellular carcinoma; microRNAs; miRs; MRMs; Myc repressed miRs

Indexed keywords

MICRORNA; MYC PROTEIN;

CANCER GROWTH; CARCINOGENESIS; CELL DIFFERENTIATION; CELL PROLIFERATION; DRUG TARGETING; GENE THERAPY; GENETIC ASSOCIATION; HOMEOSTASIS; HUMAN; LIVER CANCER; ONCOGENE; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW;

EID: 84856144003     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2011.12.023     Document Type: Article

References (17)

1. J.M. Schnater, S.E. Kohler, W.H. Lamers Where do we stand with hepatoblastoma? A review Cancer 98 2003 668 678
2. J.D. Yang, L.R. Roberts Hepatocellular carcinoma: a global view Nat Rev Gastroenterol Hepatol 7 2010 448 458
3. N. Meyer, L.Z. Penn Reflecting on 25 years with MYC Nat Rev Cancer 8 2008 976 990
4. S. Herold, B. Herkert, M. Eilers Facilitating replication under stress: an oncogenic function of MYC? Nat Rev Cancer 9 2009 441 444
5. C.M. Shachaf, A.M. Kopelman, C. Arvanitis MYC inactivation uncovers pluripotent differentiation and tumour dormancy in hepatocellular cancer Nature 431 2004 1112 1117
6. S. Beer, K. Komatsubara, D.I. Bellovin Hepatotoxin-induced changes in the adult murine liver promote MYC-induced tumorigenesis PLoS One 3 2008 e2493
7. S. Cairo, C. Armengol, A. DeReynies Hepatic stem-like phenotype and interplay of Wnt/beta-catenin and Myc signaling in aggressive childhood liver cancer Cancer Cell 14 2008 471 484
8. A. Villanueva, Y. Hoshida, C. Battiston Combining clinical, pathology, and gene expression data to predict recurrence of hepatocellular carcinoma Gastroenterology 140 2011 1501 1512
9. S. Cairo, Y. Wang, A. de Reynies Stem cell-like micro-RNA signature driven by Myc in aggressive liver cancer Proc Natl Acad Sci U S A 107 2010 20471 20476
10. S.R. Viswanathan, J.T. Powers, W. Einhorn Lin28 promotes transformation and is associated with advanced human malignancies Nat Genet 41 2009 843 848
11. D. Subramanyam, R. Blelloch From microRNAs to targets: pathway discovery in cell fate transitions Curr Opin Genet Dev 21 2011 498 503
12. M.T. Le, C. Teh, N. Shyh-Chang MicroRNA-125b is a novel negative regulator of p53 Genes Dev 23 2009 862 876
13. A.K. Nagaraja, C.J. Creighton A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer Mol Endocrinol 24 2010 447 463
14. T.V. Bui, J.T. Mendell Myc: maestro of microRNAs Genes Cancer 1 2010 568 575
15. J. Ji, J. Shi, A. Budhu MicroRNA expression, survival, and response to interferon in liver cancer N Engl J Med 361 2009 1437 1447
16. J. Kota, R.R. Chivukula, K.A. O'Donnell Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model Cell 137 2009 1005 1017
17. J. Guo, L. Bourre, D.M. Soden Can non-viral technologies knockdown the barriers to siRNA delivery and achieve the next generation of cancer therapeutics? Biotechnol Adv 29 2011 402 417