Plasmid-cured chlamydia caviae activates TLR2-dependent signaling and retains virulence in the guinea pig model of genital tract infection

PLoS ONE

Volumn 7, Issue 1, 2012, Pages

  Frazer, Lauren C ^a   Darville, Toni ^a   Chandra Kuntal, Kumar ^a   Andrews, Charles W ^b   Zurenski, Matthew ^a   Mintus, Margaret ^a   AbdelRahman, Yasser M ^c,d   Belland, Robert J ^c   Ingalls, Robin R ^e   O'Connell, Catherine M ^a  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b Milstead Pathology Group   (United States)

^c UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^d CAIRO UNIVERSITY   (Egypt)

^e BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYGLUCOSE; ESTRADIOL; NOVOBIOCIN; TOLL LIKE RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CHLAMYDIA; CHLAMYDIA CAVIAE; CHLAMYDIA TRACHOMATIS; CHLAMYDIASIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME REGULATION; FEMALE; GENE LOCUS; GENITAL TRACT INFECTION; GUINEA PIG; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PHENOTYPE; PLASMID; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SPECIES DIFFERENTIATION; ANIMAL; CELL CULTURE; CELL STRAIN HEK293; DISEASE MODEL; GENE DELETION; GENETICS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; METABOLISM; MICROBIOLOGY; MOLECULAR EVOLUTION; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; VIRULENCE;

CAVIA; CHLAMYDIA; CHLAMYDIA MURIDARUM; CHLAMYDIA TRACHOMATIS;

ANIMALS; CELLS, CULTURED; CHLAMYDIA; CHLAMYDIA INFECTIONS; DISEASE MODELS, ANIMAL; EVOLUTION, MOLECULAR; FEMALE; GENE DELETION; GUINEA PIGS; HEK293 CELLS; HUMANS; LYMPHOCYTE ACTIVATION; PLASMIDS; REPRODUCTIVE TRACT INFECTIONS; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; VIRULENCE;

EID: 84856138700     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0030747     Document Type: Article

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