The chemistry of peptidyltransferase center-targeted antibiotics: Enzymatic resistance and approaches to countering resistance

ACS Chemical Biology

Volumn 7, Issue 1, 2012, Pages 64-72

  McCusker, Kevin P ^a   Fujimori, Danica Galonić ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ANTIBIOTIC AGENT; BACTERIAL ENZYME; CYTOSINE; MACROLIDE; PEPTIDYLTRANSFERASE; PYRIMIDINE; RIBOSOME RNA; URIDINE;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; CATALYSIS; CHEMICAL LABELING; DRUG BINDING SITE; DRUG PROTEIN BINDING; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME INHIBITION; ENZYME KINETICS; ENZYME PURIFICATION; ENZYME SUBSTRATE COMPLEX; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN TARGETING; REVIEW; RIBOSOME; RNA METHYLATION; RNA PROCESSING; STRUCTURE ACTIVITY RELATION;

ACETAMIDES; ANTI-BACTERIAL AGENTS; BACTERIA; BACTERIAL INFECTIONS; BINDING SITES; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ERYTHROMYCIN; HUMANS; METHYLATION; OXAZOLIDINONES; PEPTIDYL TRANSFERASES; PROTEIN BIOSYNTHESIS; RIBOSOMES; RNA, RIBOSOMAL, 23S; TETRAZOLES;

BACTERIA (MICROORGANISMS);

EID: 84856134776     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb200418f     Document Type: Review

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