Hepatoprotective activity of Chenopodium album Linn. Against paracetamol induced liver damage

Pharmacologyonline

Volumn 3, Issue , 2011, Pages 312-328

  Nigam, Vijay ^a   Paarakh, Padmaa M ^b  

^a SRET College of Pharmacy   (India)

^b Oxford College of Pharmacy   (India)

Author keywords

Chenopodium album Linn; Hepatoprotective activity; Histopathology; Paracetamol; Serum biochemical assessment

Indexed keywords

ALANINE AMINOTRANSFERASE; ALBUMIN; ALCOHOL; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; CHENOPODIUM ALBUM EXTRACT; LIVER PROTECTIVE AGENT; PARACETAMOL; PLANT EXTRACT; PROTEIN; SILYMARIN; UNCLASSIFIED DRUG; WATER;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BILIRUBIN BLOOD LEVEL; CHENOPODIUM ALBUM; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG POTENCY; HISTOPATHOLOGY; LIVER INJURY; LIVER PROTECTION; LIVER TOXICITY; LIVER WEIGHT; NONHUMAN; PROTEIN BLOOD LEVEL; RAT; SOLVENT EXTRACTION; TOXICITY TESTING;

EID: 84856134495     PISSN: None     EISSN: 18278620     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Petri WA. Antimicrobial agents: In Gilman AG, Hardman JG, Limbird LE, Editor. The Pharmacological Basis of Therapeutics. Tenth ed. New York: McGraw-Hill publication Corporation, 2001, p. 1189-1193.
2. Nadeem M, Dandia PC, Pasha KV, Imran M, Balani DK, Vohora SB, Hepatoprotective activity of Solanum nigrum fruits. Fitoterapia, 1997; LXVIII (3): 245-251.
3. Nedialkova ZK, Nedialkov PT, Nikolov SD, The genus Chenopodium: Phytochemistry, Ethnopharmacology and Pharmacology. Phcog Rev, 2009; 3(6): 280-306.
4. Anonymous. The Wealth of India (Raw Materials), Vol. 3, New Delhi: CSIR, 2001, p. 464-469.
5. Warrier PK. Indian Medicinal Plants-A Compendium of 500 Species, Vol. 2, Chennai: Orient Longman Pvt Ltd, 2001, p. 61-62.
6. Agarwal SS, Yamrekar BP, Paridhavi M. Clinical Useful Herbal Drug, New Delhi: Ahuja Publishing House, 2005, p. 10-12.
7. Panda H. Handbook on Medicinal Herbs with Uses. New Delhi: Asia Pacific Business Press, 2005, p.325-326.
8. Pramila K, Neetu S, Anju R. Medicinal plants used in traditional health care system prevalent in Western Himalaya Indian J Traditional Knowledge, 2006;5(3): 300-309.
9. Khare CP. Indian Medicinal Plants, New Delhi: Springer International Publication, 2007, p. 141-142.
10. Rastogi RP, Mehrotra BN. Compendium of Indian Medicinal Plants, Vol. 3, reprint edn, Lucknow: CDRI, 1998, p. 162-163.
11. Della Greca M, D'Abrosca B, Fiorentino A, Previtera H, Zarrelli A. Structure elucidation and phytotoxicity of ecdysteroids from Chenopodium album. Chem Biodivers, 2005; 2(4): 457-62.
12. Della Greca M, Di Marino C, Zarrelli A, D'Abrosca B. Isolation and phytotoxicity of apocarotenoids from Chenopodium album. J Nat Prod, 2004; 67(9):1492-5.
13. Cutillo F, D'Abrosca B, Della Greca M, Zarrelli A. Chenoalbicin, a novel cinnamic acid amide alkaloid from Chenopodium album. Chem Biodivers, 2004; 1(10):1579-83.
14. Cutillo F, Della Greca M, Gionti M, Previtera H, Zarrelli A. Phenol and lignans from Chenopodium album. Phytochemical Anal, 2006; 17(5): 344-9.
15. Jhade D, Padmaa MP, Usha G. Isolation of phytoconstituents from the leaves of Chenopodium album Linn. Journal of Pharmacy Research, 2009; 2(7):1192-1193.
16. Dai Y, Ye WC, Wang ZT, Mastuda H, Kubo M, But PP. Antiprurutic and antinociceptive effect of Chenopodium album L in mice. J Ethnopharmacol, 2002; 81(2): 245-50.
17. Jabbar A, Zaman MA, Labal Z, Yaseen M, Shamin A. Anthelmintic activity of Chenopodium album L and Caesalpinia crista L against trichostrongylid nematodes of sheep. J Ethnopharmacol, 2007; 114 (1):86-91.
18. Kumar S, Biswas S, Mandal D, Roy HN, Chakraborty S, Kabir SN. Chenopodium album seed extract: a potent sperm immobilizing agent both in vivo and in vitro. Contraception, 2007; 75(1): 71-8.
19. Shenoy KA, Somayaji SN, Bairy KL. Hepatoprotective effects of Ginkgo biloba against carbon tetrachloride induced hepatic injury in rats. Indian J Pharmacology, 2001; 45(4): 435-441.
20. Mastuda H, Samukawa K, Kubo M. Anti-hepatic activity of Ginsenoside Ro. Planta Med, 1991;57: 523-526.
21. Vogel WH, Scholkens BA, Sandow J, Muller G. Drug Discovery and Evaluation; Pharmacological Assay. Second ed. New York: Spinger-Verlag Berlin Heidelberg, 2002, p.906-944.
22. Boyd EH, Bereczky GM. Liver necrosis from paracetamol. Br J Pharmacol. 1966; 26: 606-614.
23. Dahlin DC, Miwa GT, Lu AYH, Nelson SD. Nacetyl-p-benzoquinone imine: A cytochrome P-450-mediated oxidation product of acetaminophen. Proc Natl Acad Sci. 1984; 81: 1327-1331.
24. Moron MS, Depierre JW, Mannervik B. Levels of glutathione, glutathione reductase and glutathione-Stransferase activities in rat lung and liver. Biochem Biophys Acta.1979; 582: 67-78.
25. Gupta AK, Chitme H, Dass SK, Misra N. Hepatoprotective activity of Rauwolfia serpentina rhizome in paracetamol intoxicated rats. J Pharmacol Toxicol. 2006; 1: 82-88.
26. 4 induced rat liver dysfunction. Indian Drugs. 2002; 39: 333-337.
27. 4-induced liver injury in lowprotein fed rats. Phythe Res. 2005; 19: 341-345.
28. Gupta AK, Misra N. Hepatoprotective activity of aqueous ethanolic extract of Chamomile capitula in paracetamol intoxicated albino rats. American Journal of Pharmacology and Toxicology.2006; 1: 17-20.