Evaluation of predictive models in daily practice for the identification of patients with Lynch syndrome

International Journal of Cancer

Volumn 130, Issue 6, 2012, Pages 1367-1377

  Tresallet, Christophe ^a   Brouquet, Antoine ^a   Julié, Catherine ^a,b   Beauchet, Alain ^a   Vallot, Céline ^c   Ménégaux, Fabrice ^d   Mitry, Emmanuel ^a   Radvanyi, François ^c   Malafosse, Robert ^a   Rougier, Philippe ^a   Nordlinger, Bernard ^a   Laurent Puig, Pierre ^a,e   Boileau, Catherine ^a   Emile, Jean François ^a,b   Muti, Christine ^b   Penna, Christophe ^a   Hofmann Radvanyi, Hélène ^a  

^a LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^b HÔPITAL AMBROISE PARÉ   (France)

^c INSTITUT CURIE   (France)

^d ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^e HÔPITAL EUROPÉEN GEORGES POMPIDOU   (France)

Author keywords

colorectal cancer; genetic testing; Lynch syndrome; microsatellite instability; prediction models

Indexed keywords

ADULT; AGED; ARTICLE; BRAF GENE; CANCER RISK; CLINICAL EVALUATION; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION; GENETIC ANALYSIS; GENETIC SCREENING; GERM LINE; HEREDITARY NONPOLYPOSIS COLORECTAL CANCER; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE INSTABILITY; MISMATCH REPAIR; MLH1 GENE; MUTATIONAL ANALYSIS; PATIENT ASSESSMENT; PATIENT IDENTIFICATION; PREDICTION; PRIORITY JOURNAL; PROMOTER REGION; RISK ASSESSMENT; SENSITIVITY AND SPECIFICITY; SOMATIC MUTATION; TUMOR GENE;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA METHYLATION; DNA MISMATCH REPAIR; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; GERM-LINE MUTATION; HUMANS; MALE; MICROSATELLITE INSTABILITY; MIDDLE AGED; NUCLEAR PROTEINS; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS B-RAF;

EID: 84856117692     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.26144     Document Type: Article

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