Impairment of renal function using hyperoncotic colloids in a two hit model of shock: A prospective randomized study

Critical Care

Volumn 16, Issue 1, 2012, Pages

  Simon, Tim P ^a   Schuerholz, Tobias ^a   Hüter, Lars ^b   Sasse, Michael ^c   Heyder, Florian ^c   Pfister, Wolfgang ^c   Marx, Gernot ^a  

^a UNIVERSITY HOSPITAL RWTH AACHEN   (Germany)

^b Central Hospital Bad Berka   (Germany)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; CREATININE; GELATIN; HETASTARCH; INTERLEUKIN 6; N ACETYL BETA GLUCOSAMINIDASE; RINGER ACETATE; DRUG DERIVATIVE; HYDROXYETHYLSTARCH 200; PLASMA SUBSTITUTE;

ACID BASE BALANCE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTERIAL PRESSURE; ARTICLE; CENTRAL VENOUS PRESSURE; COLLOID; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ESCHERICHIA COLI; FEMALE; FIBRIN CLOT; FLUID BALANCE; FLUID RESUSCITATION; HEART OUTPUT; HEMODYNAMICS; HEMORRHAGIC SHOCK; HISTOLOGY; HYPERONCOTIC COLLOID; IN VIVO STUDY; INFLAMMATION; KIDNEY BIOPSY; KIDNEY DYSFUNCTION; KIDNEY FUNCTION; NEPHROSIS; NONHUMAN; ONCOTIC PRESSURE; OSMOSIS; PRIORITY JOURNAL; SEPTIC SHOCK; SWINE; URINE VOLUME; ANIMAL; DISEASE MODEL; DRUG EFFECT; FLUID THERAPY; KIDNEY; PATHOLOGY; PHYSIOLOGY; RANDOMIZATION;

ANIMALS; COLLOIDS; DISEASE MODELS, ANIMAL; FEMALE; FLUID THERAPY; HETASTARCH; KIDNEY; PLASMA SUBSTITUTES; RANDOM ALLOCATION; SHOCK, HEMORRHAGIC; SHOCK, SEPTIC; SWINE;

EID: 84856113810     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc11161     Document Type: Article

References (29)

1. Imm A, Carlson RW. Fluid resuscitation in circulatory shock. Crit Care Clin 1993, 9:313-333.
2. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M, . Early Goal-Directed Therapy Collaborative Group Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001, 345:1368-1377. 10.1056/NEJMoa010307, 11794169, Early Goal-Directed Therapy Collaborative Group.
3. Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M, Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL, . International Surviving Sepsis Campaign Guidelines Committee; American Association of Critical-Care Nurses; American College of Chest Physicians; American College of Emergency Physicians; Canadian Critical Care Society; European Society of Clinical Microbiology and Infectious Diseases; European Society of Intensive Care Medicine; European Respiratory Society; International Sepsis Forum; Japanese Association for Acute Medicine; Japanese Society of Intensive Care Medicine; Society of Critical Care Medicine; Society of Hospital Medicine; Surgical Infection Society; World Federation of Societies of Intensive and Critical Care Medicine Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 2008, 36:296-327. 10.1097/01.CCM.0000298158.12101.41, 18158437, International Surviving Sepsis Campaign Guidelines Committee; American Association of Critical-Care Nurses; American College of Chest Physicians; American College of Emergency Physicians; Canadian Critical Care Society; European Society of Clinical Microbiology and Infectious Diseases; European Society of Intensive Care Medicine; European Respiratory Society; International Sepsis Forum; Japanese Association for Acute Medicine; Japanese Society of Intensive Care Medicine; Society of Critical Care Medicine; Society of Hospital Medicine; Surgical Infection Society; World Federation of Societies of Intensive and Critical Care Medicine.
4. Marx G. Fluid therapy in sepsis with capillary leakage. Eur J Anaesthesiol 2003, 20:429-442. 10.1097/00003643-200306000-00002, 12803259.
5. Marx G, Hüter L, Schuerholz T. Impact of hydroxyethylstarch on renal function. The current status. Yearbook of Intensive Care and Emergency Medicine 2009, 533-543. Berlin, Heidelberg, New York: Springer Verlag, Vincent J-L.
6. Schortgen F, Lacherade JC, Bruneel F, Cattaneo I, Hemery F, Lemaire F, Brochard L. Effects of hydroxyethylstarch and gelatin on renal function in severe sepsis: a multicentre randomised study. Lancet 2001, 357:911-916. 10.1016/S0140-6736(00)04211-2, 11289347.
7. Brunkhorst FM, Engel C, Bloos F, Meier-Hellmann A, Ragaller M, Weiler N, Moerer O, Gruendling M, Oppert M, Grond S, Olthoff D, Jaschinski U, John S, Rossaint R, Welte T, Schaefer M, Kern P, Kuhnt E, Kiehntopf M, Hartog C, Natanson C, Loeffler M, Reinhart K. Intensive insulin therapy and pentastarch resuscitation in severe sepsis. N Engl J Med 2008, 358:125-139. 10.1056/NEJMoa070716, 18184958.
8. Sakr Y, Payen D, Reinhart K, Sipmann FS, Zavala E, Bewley J, Marx G, Vincent JL. Effects of hydroxyethyl starch administration on renal function in critically ill patients. Br J Anaesth 2007, 98:216-224. 10.1093/bja/ael333, 17251213.
9. Sümpelmann R, Witt L, Brütt M, Osterkorn D, Koppert W, Osthaus WA. Changes in acid-base, electrolyte and hemoglobin concentrations during infusion of hydroxyethyl starch 130/0.42/6:1 in normal saline or in balanced electrolyte solution in children. Paediatr Anaesth 2010, 20:100-104. 10.1111/j.1460-9592.2009.03197.x, 19968805.
10. Kellum JA. Saline-induced hyperchloremic metabolic acidosis. Crit Care Med 2002, 30:259-261. 10.1097/00003246-200201000-00046, 11902280.
11. Guidet B, Soni N, Della Rocca G, Kozek S, Vallet B, Annane D, James M. A balanced view of balanced solutions. Crit Care 2010, 14:325. 10.1186/cc9230, 3219243, 21067552.
12. Hüter L, Simon TP, Weinmann L, Schuerholz T, Reinhart K, Wolf G, Amann KU, Marx G. Hydroxyethylstarch impairs renal function and induces interstitial proliferation, macrophage infiltration and tubular damage in an isolated renal perfusion model. Crit Care 2009, 13:R23. 10.1186/cc7726, 2688141, 19239718.
13. Pearsons ES, Please NW. Relation between the shape of population distribution and the robustness of four simple test statistics. Biometrika 1975, 62:223-241.
14. Godet G. Hydroxyethylstarch as a risk factor for acute renal failure in severe sepsis. Lancet 2001, 358:581. author reply 582.
15. Lehmann GB, Asskali F, Boll M, Burmeister MA, Marx G, Hilgers R, Förster H. HES 130/0.42 shows less alteration of pharmacokinetics than HES 200/0.5 when dosed repeatedly. Br J Anaesth 2007, 98:635-644. 10.1093/bja/aem068, 17456491.
16. Barron J. Pharmacology of cristalloids and colloids. Transfusion Medicine and Alternative to Blood Transfusion 2000, 123-127. Paris: R&J-Editions Medicales, NATA.
17. Chinitz JL, Kim KE, Onesti G, Swartz C. Pathophysiology and prevention of dextran-40-induced anuria. J Lab Clin Med 1971, 77:76-87.
18. Schortgen F, Girou E, Deye N, Brochard L. The risk associated with hyperoncotic colloids in patients with shock. Intensive Care Med 2008, 34:2157-2168. 10.1007/s00134-008-1225-2, 18685828.
19. Stander S, Szepfalusi Z, Bohle B, Ständer H, Kraft D, Luger TA, Metze D. Differential storage of hydroxyethyl starch (HES) in the skin: an immunoelectron-microscopical long-term study. Cell Tissue Res 2001, 304:261-269. 10.1007/s004410000324, 11396719.
20. Sirtl C, Laubenthal H, Zumtobel V, Kraft D, Jurecka W. Tissue deposits of hydroxyethyl starch (HES): dose-dependent and time-related. Br J Anaesth 1999, 82:510-515.
21. Murugan R, Karajala-Subramanyam V, Lee M, Yende S, Kong L, Carter M, Angus DC, Kellum JA, . Genetic and Inflammatory Markers of Sepsis (GenIMS) Investigators Acute kidney injury in non-severe pneumonia is associated with an increased immune response and lower survival. Kidney Int 2010, 77:527-35. 10.1038/ki.2009.502, 2871010, 20032961, Genetic and Inflammatory Markers of Sepsis (GenIMS) Investigators.
22. Lv R, Zhou W, Zhang LD, Xu JG. Effects of hydroxyethyl starch on hepatic production of cytokines and activation of transcription factors in lipopolysaccharide-administered rats. Acta Anaesthesiol Scand 2005, 49:635-642. 10.1111/j.1399-6576.2005.00668.x, 15836676.
23. Davies PG, Venkatesh B, Morgan TJ, Presneill JJ, Kruger PS, Thomas BJ, Roberts MS, Mundy J. Plasma acetate, gluconate and interleukin-6 profiles during and after cardiopulmonary bypass: a comparison of Plasma-Lyte 148 with a bicarbonate-balanced solution. Crit Care 2011, 15:R21. 10.1186/cc9966, 3222055, 21235742.
24. Hoffmann JN, Vollmar B, Laschke MW, Inthorn D, Schildberg FW, Menger MD. Hydroxyethylstarch (130 kD), but not crystalloid volume support, improves microcirculation during normotensive endotoxemia. Anesthesiology 2002, 97:460-470. 10.1097/00000542-200208000-00025, 12151938.
25. Healey MA, Davis RE, Liu FC, Loomis WH, Hoyt DB. Lactated ringer's is superior to normal saline in a model of massive hemorrhage and resuscitation. J Trauma 1998, 45:894-899. 10.1097/00005373-199811000-00010, 9820700.
26. Sakka SG, Bredle DL, Reinhart K, Meier-Hellmann A. Comparison between intrathoracic blood volume and cardiac filling pressures in the early phase of hemodynamic instability of patients with sepsis or septic shock. J Crit Care 1999, 14:78-83. 10.1016/S0883-9441(99)90018-7, 10382788.
27. Lichtwarck-Aschoff M, Zeravik J, Pfeiffer UJ. Intrathoracic blood volume accurately reflects circulatory volume status in critically ill patients with mechanical ventilation. Intensive Care Med 1992, 18:142-147. 10.1007/BF01709237, 1644961.
28. Diodato MD, Knoferl MW, Schwacha MG, Bland KI, Chaudry IH. Gender differences in the inflammatory response and survival following haemorrhage and subsequent sepsis. Cytokine 2001, 14:162-169. 10.1006/cyto.2001.0861, 11396994.
29. Knoferl MW, Angele MK, Diodato MD, Schwacha MG, Ayala A, Cioffi WG, Bland KI, Chaudry IH. Female sex hormones regulate macrophage function after trauma-hemorrhage and prevent increased death rate from subsequent sepsis. Ann Surg 2002, 235:105-112. 10.1097/00000658-200201000-00014, 1422402, 11753049.