Breast cancer following diethylstilbestrol exposure in utero: Insights from a tragedy

European Journal of Epidemiology

Volumn 27, Issue 1, 2012, Pages 1-3

  Adami, Hans Olov ^a,b   Lagiou, Pagona ^a,c   Trichopoulos, Dimitrios ^a  

^a HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Breast cancer; DES; Diethylstilbestrol; Estrogens; In utero

Indexed keywords

DIETHYLSTILBESTROL;

BREAST CANCER; CANCER RISK; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; HUMAN; MEDICAL RESEARCH; NOTE; PRENATAL DRUG EXPOSURE; STATISTICAL ANALYSIS; SYSTEMATIC ERROR; VAGINA CANCER;

BREAST NEOPLASMS; DIETHYLSTILBESTROL; ESTROGENS, NON-STEROIDAL; FEMALE; HUMANS; PREGNANCY; PREGNANCY COMPLICATIONS; PRENATAL EXPOSURE DELAYED EFFECTS;

EID: 84856087015     PISSN: 03932990     EISSN: 15737284     Source Type: Journal    
DOI: 10.1007/s10654-012-9655-0     Document Type: Note

References (13)

1. Palmer JR, Wise LA, Hatch EE, Troisi R, Titus-Ernstoff L, Strohsnitter W, et al. Prenatal diethylstilbestrol exposure and risk of breast cancer. Cancer Epidemiol Biomarkers Prev. 2006;15:1509-14. (Pubitemid 44299324)
2. Hoover RN, Hyer M, Pfeiffer RM, Adam E, Bond B, Cheville AL, et al. Adverse health outcomes in women exposed in utero to diethylstilbestrol. N Engl J Med. 2011;365:1304-14.
3. Greenberg ER, Barnes AB, Resseguie L, Barrett JA, Burnside S, Lanza LL, et al. Breast cancer in mothers given diethylstilbestrol in pregnancy. N Engl J Med. 1984;311:1393-8. (Pubitemid 15175270)
4. Herbst AL, Ulfelder H, Poskanzer DC. Adenocarcinoma of the vagina. Association of maternal stilbestrol therapy with tumor appearance in young women. N Engl J Med. 1971;284:878-81.
5. Weiss HA, Potischman NA, Brinton LA, Brogan D, Coates RJ, Gammon MD, et al. Prenatal and perinatal risk factors for breast cancer in young women. Epidemiology. 1997;8:181-7. (Pubitemid 27084190)
6. Hatch EE, Palmer JR, Titus-Ernstoff L, Noller KL, Kaufman RH, Mittendorf R, et al. Cancer risk in women exposed to diethylstilbestrol in utero. JAMA. 1998;280:630-4. (Pubitemid 28502640)
7. Palmer JR, Hatch EE, Rosenberg CL, Hartge P, Kaufman RH, Titus-Ernstoff L, et al. Risk of breast cancer in women exposed to diethylstilbestrol in utero: preliminary results (United States). Cancer Causes Control. 2002;13:753-8. (Pubitemid 35204051)
8. Trichopoulos D. Hypothesis: does breast cancer originate in utero? Lancet. 1990;335(8695):939-40. (Pubitemid 20134970)
9. Lagiou P, Adami HO, Trichopoulos D. Causality in cancer epidemiology. Eur J Epidemiol. 2005;20:565-74. (Pubitemid 41130750)
10. Verloop J, van Leeuwen FE, Helmerhorst TJ, van Boven HH, Rookus MA. Cancer risk in DES daughters. Cancer Causes Control. 2010;21:999-1007.
11. Rothman KJ. Modern epidemiology. Boston: Little Brown; 1986. p. 19.
12. Trichopoulos D, Adami HO, Ekbom A, Hsieh CC, Lagiou P. Early life events and conditions and breast cancer risk: from epidemiology to etiology. Int J Cancer. 2008;122:481-5. (Pubitemid 350308937)
13. Smith OW, Smith GV, Hurwitz D. Increased excretion of pregnanediol in pregnancy from diethylstilbestrol with special reference to the prevention of late pregnancy accidents. Am J Obstet Gynecol. 1946;51:411-5.