Retroviral delivery of platelet-derived growth factor to spinal cord progenitor cells drives the formation of intramedullary gliomas

Neurosurgery

Volumn 70, Issue 1, 2012, Pages 198-204

  Ellis, Jason A ^a   Castelli, Michael ^a   Bruce, Jeffrey N ^a   Canoll, Peter ^b   Ogden, Alfred T ^a  

^a NEUROLOGICAL INSTITUTE   (United States)

^b NewYork Presbyterian Hospital   (United States)

Author keywords

Astrocytoma; Ependymoma; Glioma; NG2; Platelet derived growth factor; Spinal cord tumor; Stem cell

Indexed keywords

GREEN FLUORESCENT PROTEIN; PLATELET DERIVED GROWTH FACTOR; PLATELET DERIVED GROWTH FACTOR B; RETROVIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL TYPE; GLIA CELL; GLIOMA; IMMUNOFLUORESCENCE; IMMUNOPHENOTYPING; INTRAMEDULLARY GLIOMA; MORBIDITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; RAT; SPINAL CORD; STEM CELL; TUMOR GROWTH; VIRAL GENE DELIVERY SYSTEM; WHITE MATTER;

ANIMALS; ANTIGENS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BROMODEOXYURIDINE; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOMA; GREEN FLUORESCENT PROTEINS; NERVE TISSUE PROTEINS; PLATELET-DERIVED GROWTH FACTOR; PROTEOGLYCANS; RATS; RATS, INBRED F344; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; RETROVIRIDAE; SPINAL CORD NEOPLASMS; STEM CELLS; TIME FACTORS;

EID: 84856080676     PISSN: 0148396X     EISSN: None     Source Type: Journal    
DOI: 10.1227/NEU.0b013e31822ce963     Document Type: Article

References (28)

1. Miller DC. Surgical pathology of intramedullary spinal cord neoplasms. J Neu-rooncol. 2000;47(3):189-194.
2. Isaacson SR. Radiation therapy and the management of intramedullary spinal cord tumors. J Neurooncol. 2000;47(3):231-238.
3. Balmaceda C. Chemotherapy for intramedullary spinal cord tumors. J Neurooncol. 2000;47(3):293-307.
4. Assanah M, Lochhead R, Ogden A, Bruce J, Goldman J, Canoll P. Glial pro¬genitors in adult white matter are driven to form malignant gliomas by platelet-derived growth factor-expressing retroviruses. J Neurosci. 2006;26(25):6781-6790. (Pubitemid 44315239)
5. Canoll P, Goldman JE. The interface between glial progenitors and gliomas. Acta Neuropathol. 2008;116(5):465-477.
6. Dai C, Celestino JC, Okada Y, Louis DN, Fuller GN, Holland EC. PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligoden-drogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo. Genes Dev. 2001;15(15):1913-1925. (Pubitemid 32738621)
7. Shih AH, Dai C, Hu X, Rosenblum MK, Koutcher JA, Holland EC. Dose-dependent effects of platelet-derived growth factor-B on glial tumorigenesis. Cancer Res. 2004;64(14):4783-4789. (Pubitemid 38924521)
8. Uhrbom L, Hesselager G, Nister M, Westermark B. Induction of brain tumors in mice using a recombinant platelet-derived growth factor B-chain retrovirus. Cancer Res. 1998;58(23):5275-5279. (Pubitemid 28551098)
9. Fakhrai N, Neophytou P, Dieckmann K, et al. Recurrent spinal ependymoma showing partial remission under Imatimib. Acta neurochirurgica. 2004;146(11):1255-1258. (Pubitemid 39517799)
10. Hitoshi Y, Harris BT, Liu H, Popko B, Israel MA. Spinal glioma: platelet-derived growth factor B-mediated oncogenesis in the spinal cord. Cancer Res. 2008;68(20):8507-8515.
11. Kakita A, Goldman JE. Patterns and dynamics of SVZ cell migration in the postnatal forebrain: monitoring living progenitors in slice preparations. Neuron. 1999;23(3):461-472. (Pubitemid 29359918)
12. Angelastro JM, Canoll PD, Kuo J, et al. Selective destruction of glioblastoma cells by interference with the activity or expression of ATF5. Oncogene. 2006;25(6):907-916. (Pubitemid 43237709)
13. Caplan J, Pradilla G, Hdeib A, et al. A novel model of intramedullary spinal cord tumors in rats: functional progression and histopathological characterization. Neurosurgery. 2006;59(1):193-200; discussion 193-200.
14. Mavinkurve G, Pradilla G, Legnani FG, et al. A novel intramedullary spinal cord tumor model: functional, radiological, and histopathological characterization. J Neurosurg Spine. 2005;3(2):142-148.
15. Salcman M, Botero E, Rao KC, Broadwell RD, Scott E. Intramedullary canine spinal cord tumor model. J Neurosurg. 1984;61(4):761-766. (Pubitemid 14000612)
16. Ren TJ, Wang ZC, Zhang YZ, Li D, Wang HY, Li ZZ. Establishment of intramedullary spinal cord glioma model in rats. Chin Med J (Engl). 2010;123(18): 2580-2585.
17. Rabotti GF, Grove AS Jr, Sellers RL, Anderson WR. Induction of multiple brain tumours (gliomata and leptomeningeal sarcomata) in dogs by Rous sarcoma virus. Nature. 1966;209(5026):884-886.
18. Salcman M, Scott EW, Schepp RS, Knipp HC, Broadwell RD. Transplantable canine glioma model for use in experimental neuro-oncology. Neurosurgery. 1982;11(3):372-381. (Pubitemid 12019409)
19. Johansson FK, Goransson H, Westermark B. Expression analysis of genes involved in brain tumor progression driven by retroviral insertional mutagenesis in mice. Oncogene. 2005;24(24):3896-3905. (Pubitemid 40896401)
20. Masui K, Suzuki SO, Torisu R, Goldman JE, Canoll P, Iwaki T. Glial progenitors in the brainstem give rise to malignant gliomas by platelet-derived growth factor stimulation. Glia. 2010;58(9):1050-1065.
21. Assanah MC, Bruce JN, Suzuki SO, Chen A, Goldman JE, Canoll P. PDGF stimulates the massive expansion of glial progenitors in the neonatal forebrain. Glia. 2009;57(16):1835-1847.
22. Beadle C, Assanah MC, Monzo P, Vallee R, Rosenfeld SS, Canoll P. The role of myosin II in glioma invasion of the brain. Mol Biol Cell. 2008;19(8):3357-3368.
23. Lin G, Goldman JE. An FGF-responsive astrocyte precursor isolated from the neonatal forebrain. Glia. 2009;57(6):592-603.
24. Horky LL, Galimi F, Gage FH, Horner PJ. Fate of endogenous stem/progenitor cells following spinal cord injury. J Comp Neurol. 2006;498(4):525-538. (Pubitemid 44232692)
25. Ohori Y, Yamamoto S, Nagao M, et al. Growth factor treatment and genetic manipulation stimulate neurogenesis and oligodendrogenesis by endogenous neural progenitors in the injured adult spinal cord. J Neurosci. 2006;26(46):11948- 11960. (Pubitemid 44772106)
26. Yamamoto S, Yamamoto N, Kitamura T, Nakamura K, Nakafuku M. Pro¬liferation of parenchymal neural progenitors in response to injury in the adult rat spinal cord. Exp Neurol. 2001;172(1):115-127. (Pubitemid 33141159)
27. Horner PJ, Power AE, Kempermann G, et al. Proliferation and differentiation of progenitor cells throughout the intact adult rat spinal cord. J Neurosci. 2000;20(6):2218-2228. (Pubitemid 30230075)
28. Louis DN, International Agency for Research on Cancer, World Health Orga¬nization. WHO Classification of Tumours of the Central Nervous System. 4th ed. Lyon, France: International Agency for Research on Cancer; 2007.