Effects of tetanus toxin on spontaneous and evoked transmitter release at inhibitory and excitatory synapses in the rat SDCN neurons

Toxicon

Volumn 59, Issue 3, 2012, Pages 385-392

  Shin, Min Chul ^a   Nonaka, Kiku ^a   Wakita, Masahito ^a   Yamaga, Toshitaka ^a   Torii, Yasushi ^b   Harakawa, Tetsuhiro ^b   Ginnaga, Akihiro ^b   Ito, Yushi ^a   Akaike, Norio ^a  

^a KUMAMOTO HEALTH SCIENCE UNIVERSITY   (Japan)

^b Kaketsuken   (Japan)

Author keywords

Evoked IPSC and EPSC; Focal electrical stimulation; Miniature IPSC and EPSC; Spinal nerve ending; Tetanus toxin

Indexed keywords

GLUTAMATE RECEPTOR; GLYCINE RECEPTOR; TETANUS TOXIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CONCENTRATION RESPONSE; CONTROLLED STUDY; ELECTROSTIMULATION; EXCITATORY POSTSYNAPTIC POTENTIAL; INHIBITORY POSTSYNAPTIC POTENTIAL; MOLECULAR DYNAMICS; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTIC INHIBITION; VOLTAGE CLAMP;

ANIMALS; BOTULINUM TOXINS, TYPE A; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; EXCITATORY AMINO ACID AGENTS; EXCITATORY POSTSYNAPTIC POTENTIALS; GLYCINE AGENTS; MINIATURE POSTSYNAPTIC POTENTIALS; NEURONS; PATCH-CLAMP TECHNIQUES; PRESYNAPTIC TERMINALS; RATS; RATS, WISTAR; SPINAL CORD; SYNAPSES; TETANUS TOXIN;

RATTUS;

EID: 84856069772     PISSN: 00410101     EISSN: 18793150     Source Type: Journal    
DOI: 10.1016/j.toxicon.2011.12.009     Document Type: Article

References (32)

1. Akaike N., Harata N. Nystatin perforated patch recording and its applications to analyses of intracellular mechanisms. Jpn. J. Physiol. 1994, 44:433-473.
2. Akaike N., Murakami N., Katsurabayashi S., Jin Y.H., Imazawa T. Focal stimulation of single GABAergic presynaptic boutons on the rat hippocampal neuron. Neurosci. Res. 2002, 42:187-195.
3. Akaike N., Moorhouse A.J. Techniques: applications of the nerve-bouton preparation in neuropharmacology. Trends Pharmacol. Sci. 2003, 24:44-47.
4. Akaike N., Ito Y., Shin M.-C., Nonaka K., Torii Y., Harakawa T., Ginnaga A., Kozaki S., Kaji R. Effects of A2 type botulinum toxin on spontaneous miniature and evoked transmitter release from the rat spinal excitatory and inhibitory synapses. Toxicon 2010, 56:1315-1326.
5. Bergey G.K., Bigalke H., Nelson P.G. Differential effects of tetanus toxin on inhibitory and excitatory synaptic transmission in mammalian spinal cord neurons in culture: a presynaptic locus of action for tetanus toxin. J. Neurophysiol. 1987, 57:121-131.
6. Bigalke H., Heller I., Bizzini B., Habermann E. Tetanus toxin and botulinum A toxin inhibit release and uptake of various transmitters, as studied with particulate preparations from rat brain and spinal cord. Naunyn-Schmiedeberg's Arch. Pharmacol. 1981, 316:244-251.
7. 2+ sensor for transmitter release at a central synapse. Cell 1994, 79:717-727.
8. Gregory K.B., Bigalke H., Nelson P.G. Differential effects of tetanus toxin on inhibitory and excitatory synaptic transmission in mammalian spinal cord neurons in culture: a presynaptic locus of action for tetanus toxin. J. Neurophysiol. 1987, 57:121-131.
9. Jang I.S., Rhee J.S., Watanabe T., Akaike N., Akaike N. Histaminergicmodulation of GABAergic transmission in rat ventromedial hypothalamic neurons. J. Physiol. 2001, 534:791-803.
10. Johnson E.A. Clostridial toxins as therapeutic agents: benefits of nature's most toxic proteins. Annu. Rev. Microbiol. 1999, 53:551-575.
11. Kanda K., Takano K. Effect of tetanus toxin on the excitatory and the inhibitory post-synaptic potentials in the cat motoneurone. J. Physiol. 1983, 335:319-333.
12. Katsurabayashi S., Kubota H., Higashi H., Akaike N., Ito Y. Distinct profiles of refilling of inhibitory neurotransmitters into presynaptic terminals projecting to spinal neurons in immature rats. J. Physiol. 2004, 560:469-478.
13. Maeda M., Tanaka E., Shoudai K., Nonaka K., Murayama N., Ito Y., Akaike N. Differential effects of divalent cations on spontaneous and evoked glycine release from spinal interneurons. J. Neurophysiol. 2009, 101:1103-1113.
14. Matsuda M., Yoneda M. Dissociation of tetanus neurotoxin into two polypeptide fragments. Biochem. Biophys. Res. Commun. 1974, 57:1257-1262.
15. Matsuda M., Sugimoto N., Ozutsumi K., Hirai T. Acute botulinum-like intoxication by tetanus neurotoxin in mice. Biochem. Biophys. Res. Commun. 1982, 104:799-805.
16. McMahon H.T., Foran P., Dolly J.O., Verhage M., Wiegant V.M., Nicholls D.G. Tetanus toxin and botulinum toxins type A and B inhibit glutamate, gamma-aminobutyric acid, aspartate, and metenkephalin release from synaptosomes. Clues to the locus of action. J. Biol. Chem. 1992, 267:21338-21343.
17. Padfield P.J. A tetanus toxin sensitive protein other than VAMP 2 is required for exocytosis in the pancreatic acinar cell. FEBS Lett. 2000, 484:129-132.
18. Pellizzari R., Rossetto O., Schiavo G., Montecucco C. Tetanus and botulinum neurotoxins: mechanisms of action and therapeutic uses. Philos. Trans. R. Soc. London Ser. B 1999, 354:259-268.
19. Rhee J.S., Ishibasi H., Akaike N. Calcium channels in the GABAergic presynaptic nerve terminals projecting to mynert neurons of the rat. J. Neurochem. 1999, 72:800-807.
20. Rizo J., Rosenmund C. Synaptic vesicle fusion. Nat. Struct. Mol. Biol. 2008, 15:665-674.
21. 2+-dependent binding of synaptotagmin to SNARE complexes. J. Biol. Chem. 2000, 275:6328-6336.
22. Schiavo G., Matteoli M., Montecucco C. Neurotoxins affecting neuroexocytosis. Physiol. Rev. 2000, 80:717-766.
23. Schiavo G., Benfenati F., Poulain B., Rossetto O., Polverino de Laureto P., DasGupta B.R., Montecucco C. Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin. Nature 1992, 359:832-835.
24. A receptor by intracellular ATP inn dissociated nucleus tractus solitarii neurons of rat. J. Physiol. 1992, 449:551-572.
25. Sobel J. Botulism. Clin. Infect. Dis. 2005, 41:1167-1173.
26. Sollner T.H. Regulated exocytosis and SNARE fusion. Mol. Membr. Biol. 2003, 20:209-220.
27. Südhof T.C., De Camilli P., Niemann H., Jahn R. Membrane fusion machinery: insights from synaptic proteins. Cell 1993, 75:1-4.
28. Südhof T.C. The synaptic vesicle cycle: a cascade of protein-protein interactions. Nature 1995, 375:645-653.
29. Takano K., Kirchner F., Terhaar P., Tiebert B. Effect of tetanus toxin on the monosynaptic reflex. Naunyn-Schmiedeberg's Arch. Pharmacol. 1983, 323:217-220.
30. Williamson L.C., Fitzgerald S.C., Neale E.A. Differential effects of tetanus toxin on inhibitory and excitatory neurotransmitter release from mammalian spinal cord cells in culture. J. Neurochem. 1992, 59:2148-2157.
31. 2+-sensor for spontaneous release. Nat. Neurosci. 2009, 12:756-766.
32. Yoshihara M., Adolfsen B., Littleton J.T. Is synaptotagmin the calcium sensor. Curr. Opin. Neurobiol. 2003, 13:315-323.