The impact of topiramate (Topamax®) therapy on the development of aggressive and/or agitated behavior

Journal of Pharmacy Practice

Volumn 24, Issue 6, 2011, Pages 568-570

  Farinde, Abimbola ^a  

^a Lufkin State Supported Living Center   (United States)

Author keywords

aggression; agitation; antiepileptic; behavioral disturbances; topiramate

Indexed keywords

AMPHETAMINE PLUS DEXAMPHETAMINE; CARBAMAZEPINE; CLONIDINE; LISINOPRIL; OXCARBAZEPINE; PLACEBO; PROPRANOLOL; RISPERIDONE; TOPIRAMATE; VALPROATE SEMISODIUM; VALPROIC ACID;

AGGRESSION; AGITATION; ANAMNESIS; ARTICLE; ATTENTION DEFICIT DISORDER; BEHAVIOR DISORDER; CLUSTER HEADACHE; COMPUTER ASSISTED TOMOGRAPHY; DOSE RESPONSE; DRUG DOSE INCREASE; DRUG MECHANISM; ELECTROENCEPHALOGRAM; FOCAL EPILEPSY; HUMAN; HYPERTENSION; MIGRAINE; NEUROPATHIC PAIN; TONIC CLONIC SEIZURE;

EID: 84856041429     PISSN: 08971900     EISSN: 15311937     Source Type: Journal    
DOI: 10.1177/0897190011416672     Document Type: Article

References (10)

1. DRUGDEX® System [Internet database]. Greenwood Village, Co: Thomson Micromedex; 2010.
2. Varghese BS, Rajeev A, Norrish M, et al. Topiramate for anger control: a systematic review. Indian J Pharmacol. 2010 ; 42 (3). 135-141
3. Guay DR.. Newer antiepileptic drugs in the management of agitation/aggression in patients with dementia or developmental disability. Consult Pharm. 2007 ; 22 (12). 1004-1034 (Pubitemid 350291261)
4. Hudson, Ohio: Lexi-Comp, Inc ; 2004 :
5. Lane SD, Gowin JL, Green CE, et al. Acute topiramate differentially affects human aggressive responding at low versus moderate doses in subjects with histories of substance abuse and antisocial behavior. Pharmacol Biochem Behav. 2009 ; 92 (2). 357-362
6. Singh T.. Topiramate and psychosis. Psychiatry (Edgmont). 2006 ; 3 (12). 10-17
7. Product Information: TOPAMAX(R) oral tablets, oral sprinkle capsules, topiramate oral tablets, oral sprinkle capsules. Titusville, NJ: Ortho-McNeil Neurologics Inc ; 2008 :
8. Khan A, Faught E, Gilliam F, et al. Acute psychotic symptoms induced by topiramate. Seizure. 1999 ; 8 (4). 235-237 (Pubitemid 29401589)
9. Jośe RJ, Calms A, Babbs C.. Topiramate-induced psychosis in two members of the one family A case report. J Med Case Rep. 2008 ; 6 (2). 195
10. Verhoeven WM, Boermans JA, Van der Heijen FM, et al. Psychosis following treatment with topiramate. Ned Tijdsche Geneeskd. 2003 ; 147 (7). 319-320