-
1
-
-
77953359099
-
Multiple molecular mechanisms underlying trastuzumab and lapatinib resistance in JIMT-1 breast cancer cells
-
Köninki K, Barok M, Tanner M et al (2010) Multiple molecular mechanisms underlying trastuzumab and lapatinib resistance in JIMT-1 breast cancer cells. Cancer Lett 294:211-219
-
(2010)
Cancer Lett
, vol.294
, pp. 211-219
-
-
Köninki, K.1
Barok, M.2
Tanner, M.3
-
3
-
-
15244363849
-
+ malignant B cells and bypass complement-mediated rituximab resistance in vitro
-
DOI 10.1016/j.exphem.2005.01.007
-
Gall JM, Davol PA, Grabert RC et al (2005) T cells armed with anti-CD3 x anti-CD20 bispecific antibody enhance killing of CD20+ malignant B cells and bypass complement-mediated rituximab resistance in vitro. Exp Hematol 33:452-459 (Pubitemid 40387628)
-
(2005)
Experimental Hematology
, vol.33
, Issue.4
, pp. 452-459
-
-
Gall, J.M.1
Davol, P.A.2
Grabert, R.C.3
Deaver, M.4
Lum, L.G.5
-
4
-
-
0032944540
-
Antibody dependent cellular phagocytosis (ADCP) and antibody dependent cellular cytotoxicity (ADCC) of breast cancer cells mediated by bispecific antibody, MDX-210
-
DOI 10.1023/A:1006145507567
-
Watanabe M, Wallace PK, Keler T et al (1999) Antibody dependent cellular phagocytosis (ADCP) and antibody dependent cellular cytotoxicity (ADCC) of breast cancer cells mediated by bispecific antibody, MDX-210. Breast Cancer Res Treat 53:199-207 (Pubitemid 29209889)
-
(1999)
Breast Cancer Research and Treatment
, vol.53
, Issue.3
, pp. 199-207
-
-
Watanabe, M.1
Wallace, P.K.2
Keler, T.3
Deo, Y.M.4
Akewanlop, C.5
Hayes, D.F.6
-
5
-
-
0242684481
-
Efficient tumor cell lysis by autologous, tumor-resident T lymphocytes in primary ovarian cancer samples by an EP-CAM-/CD3-bispecific antibody
-
DOI 10.1002/ijc.11056
-
Wimberger P, Xiang W, Mayr D et al (2003) Efficient tumour cell lysis by autologous, tumourresident T lymphocytes in primary ovarian cancer samples by an EP-CAM-/CD3-bispecific antibody. Int J Cancer 105:241-248 (Pubitemid 36505328)
-
(2003)
International Journal of Cancer
, vol.105
, Issue.2
, pp. 241-248
-
-
Wimberger, P.1
Xiang, W.2
Mayr, D.3
Diebold, J.4
Dreier, T.5
Baeuerle, P.A.6
Kimmig, R.7
-
6
-
-
33645690747
-
Enhanced killing of primary ovarian cancer by retargeting autologous cytokine-induced killer cells with bispecific antibodies: A preclinical study
-
Chan JK, Hamilton CA, Cheung MK et al (2006) Enhanced killing of primary ovarian cancer by retargeting autologous cytokine-induced killer cells with bispecific antibodies: a preclinical study. Clin Cancer Res 12:1859-1867
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1859-1867
-
-
Chan, J.K.1
Hamilton, C.A.2
Cheung, M.K.3
-
7
-
-
30344441648
-
Anti-CD3 x anti-epidermal growth factor receptor (EGFR) bispecific antibody redirects T-cell cytolytic activity to EGFR-positive cancers in vitro and in an animal model
-
DOI 10.1158/1078-0432.CCR-05-1855
-
Reusch U, Sundaram M, Davol PA et al (2006) Anti-CD3 x anti-epidermal growth factor receptor (EGFR) bispecific antibody redirects T-cell cytolytic activity to EGFR-positive cancers in vitro and in an animal model. Clin Cancer Res 12:183-190 (Pubitemid 43166193)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.1
, pp. 183-190
-
-
Reusch, U.1
Sundaram, M.2
Davol, P.A.3
Olson, S.D.4
Davis, J.B.5
Demel, K.6
Nissim, J.7
Rathore, R.8
Liu, P.Y.9
Lum, L.G.10
-
8
-
-
77956344338
-
Development and approval of the trifunctional antibody catumaxomab (anti-EpCAMxanti-CD3) as a targeted cancer immunotherapy
-
Seimetz D, Lindhofer H, Bokemeyer C (2010) Development and approval of the trifunctional antibody catumaxomab (anti-EpCAMxanti-CD3) as a targeted cancer immunotherapy. Cancer Treat Rev 36:458-467
-
(2010)
Cancer Treat Rev
, vol.36
, pp. 458-467
-
-
Seimetz, D.1
Lindhofer, H.2
Bokemeyer, C.3
-
9
-
-
77954676136
-
The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: Results of a prospective randomized phase II/III trial
-
Heiss MM, Murawa P, Koralewski P et al (2010) The trifunctional antibody catumaxomab for the treatment of malignant ascites due to epithelial cancer: results of a prospective randomized phase II/III trial. Int J Cancer 127:2209-2221
-
(2010)
Int J Cancer
, vol.127
, pp. 2209-2221
-
-
Heiss, M.M.1
Murawa, P.2
Koralewski, P.3
-
10
-
-
0033178740
-
Simultaneous activation of T cells and accessory cells by a new class of intact bispecific antibody results in efficient tumor cell killing
-
Zeidler R, Reisbach G, Wollenberg B et al (1999) Simultaneous activation of T-cells and accessory cells by a new class of intact bi-specific antibody results in efficient tumor cell killing. J Immunol 163:1246-1252 (Pubitemid 29352740)
-
(1999)
Journal of Immunology
, vol.163
, Issue.3
, pp. 1246-1252
-
-
Zeidler, R.1
Reisbach, G.2
Wollenberg, B.3
Lang, S.4
Chaubal, S.5
Schmitt, B.6
Lindhofer, H.7
-
11
-
-
0034051390
-
The Fc-region of a new class of intact bispecific antibody mediates activation of accessory cells and NK cells and induces direct phagocytosis of tumour cells
-
Zeidler R, Mysliwietz J, Csanady M et al (2000) The Fc-region of a new class of intact bi-specific antibody mediates activation of accessory cells and NK cells and induces direct phagocytosis of tumor cells. Br J Cancer 83:261-266 (Pubitemid 30411727)
-
(2000)
British Journal of Cancer
, vol.83
, Issue.2
, pp. 261-266
-
-
Zeidler, R.1
Mysliwietz, J.2
Csanady, M.3
Walz, A.4
Ziegler, I.5
Schmitt, B.6
Wollenberg, B.7
Lindhofer, H.8
-
12
-
-
0035528821
-
TNFα contributes to the antitumor activity of a bispecific, trifunctional antibody
-
Zeidler R, Mayer A, Gires O et al (2001) TNFalpha contributes to the anti-tumor activity of a bispecific, trifunctional antibody. Anticancer Res 21:3499-3503 (Pubitemid 34224257)
-
(2001)
Anticancer Research
, vol.21
, Issue.5
, pp. 3499-3503
-
-
Zeidler, R.1
Mayer, A.2
Gires, O.3
Schmitt, B.4
Mack, B.5
Lindhofer, H.6
Wollenberg, B.7
Walz, A.8
-
13
-
-
34547579096
-
Characterisation of the new EpCAM-specific antibody HO-3: Implications for trifunctional antibody immunotherapy of cancer
-
DOI 10.1038/sj.bjc.6603881, PII 6603881
-
Ruf P, Gires O, Jäger M et al (2007) Characterisation of the new EpCAM-specifi c antibody HO-3: implications for trifunctional antibody immunotherapy of cancer. Br J Cancer 97:315-321 (Pubitemid 47196752)
-
(2007)
British Journal of Cancer
, vol.97
, Issue.3
, pp. 315-321
-
-
Ruf, P.1
Gires, O.2
Jager, M.3
Fellinger, K.4
Atz, J.5
Lindhofer, H.6
-
14
-
-
0026565680
-
Recovery of blood B-lymphocytes and serum immunoglobulins after chemotherapy for childhood acute lymphoblastic leukemia
-
Alanko S, Pelliniemi TT, Salmi TT (1992) Recovery of blood B-lymphocytes and serum immunoglobulins after chemotherapy for childhood acute lymphoblastic leukemia. Cancer 69:1481-1486
-
(1992)
Cancer
, vol.69
, pp. 1481-1486
-
-
Alanko, S.1
Pelliniemi, T.T.2
Salmi, T.T.3
-
15
-
-
18844428908
-
Immune dysfunction and micrometastases in women with breast cancer
-
DOI 10.1007/s10549-004-7048-0
-
Campbell MJ, Scott J, Maecker HT (2005) Immune dysfunction and micrometastases in women with breast cancer. Breast Cancer Res Treat 91:163-171 (Pubitemid 40684928)
-
(2005)
Breast Cancer Research and Treatment
, vol.91
, Issue.2
, pp. 163-171
-
-
Campbell, M.J.1
Scott, J.2
Maecker, H.T.3
Park, J.W.4
Esserman, L.J.5
-
16
-
-
3242780152
-
Assessment of humoral immunity to poliomyelitis, tetanus, hepatitis B, measles, rubella, and mumps in children after chemotherapy
-
DOI 10.1002/cncr.20384
-
Zignol M, Peracchi M, Tridello G et al (2004) Assessment of humoral immunity to poliomyelitis, tetanus, hepatitis B, measles, rubella, and mumps in children after chemotherapy. Cancer 101:635-641 (Pubitemid 38970616)
-
(2004)
Cancer
, vol.101
, Issue.3
, pp. 635-641
-
-
Zignol, M.1
Peracchi, M.2
Tridello, G.3
Pillon, M.4
Fregonese, F.5
D'Elia, R.6
Zanesco, L.7
Cesaro, S.8
-
17
-
-
0032954895
-
Phase I/IIa study of concurrent paclitaxel and cisplatin with radiation therapy m locally advanced non-small cell lung cancer: Analysis of early and late pulmonary morbidity
-
Robert F, Childs HA, Spencer SA et al (1999) Phase I/IIa study of concurrent paclitaxel and cisplatin with radiation therapy in locally advanced non-small cell lung cancer: analysis of early and late pulmonary morbidity. Semin Radiat Oncol 9:136-147 (Pubitemid 29190424)
-
(1999)
Seminars in Radiation Oncology
, vol.9
, Issue.2 SUPPL. 1
, pp. 136-147
-
-
Robert, F.1
Childs, H.A.2
Spencer, S.A.3
Redden, D.T.4
Hawkins, M.M.5
-
18
-
-
0028359989
-
Recovery of blood T-cell subsets after chemotherapy for childhood acute lymphoblastic leukemia
-
Alanko S, Salmi TT, Pelliniemi TT (1994) Recovery of blood T-cell subsets after chemotherapy for childhood acute lymphoblastic leukemia. Pediatr Hematol Oncol 11:281-292 (Pubitemid 24153140)
-
(1994)
Pediatric Hematology and Oncology
, vol.11
, Issue.3
, pp. 281-292
-
-
Alanko, S.1
Salmi, T.T.2
Pelliniemi, T.-T.3
-
19
-
-
77649293757
-
Association of nutritional status and serum albumin levels with development of toxicity in patients with advanced non-small cell lung cancer treated with paclitaxelcisplatin chemotherapy: A prospective study
-
Arrieta O, Michel Ortega RM, Villanueva-Rodríguez G et al (2010) Association of nutritional status and serum albumin levels with development of toxicity in patients with advanced non-small cell lung cancer treated with paclitaxelcisplatin chemotherapy: a prospective study. BMC Cancer 10:50
-
(2010)
BMC Cancer
, vol.10
, pp. 50
-
-
Arrieta, O.1
Michel Ortega, R.M.2
Villanueva-Rodríguez, G.3
-
20
-
-
51549103264
-
Immune defects in breast cancer patients after radiotherapy
-
Standish LJ, Torkelson C, Hamill FA et al (2008) Immune defects in breast cancer patients after radiotherapy. J Soc Integr Oncol 6:110-121
-
(2008)
J Soc Integr Oncol
, vol.6
, pp. 110-121
-
-
Standish, L.J.1
Torkelson, C.2
Hamill, F.A.3
-
21
-
-
0034088892
-
Molecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate synthase inhibitor raltitrexed
-
DOI 10.1016/S0959-8049(00)00026-5, PII S0959804900000265
-
Peters GJ, van Triest B, Backus HH et al (2000) Molecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate synthase inhibitor raltitrexed. Eur J Cancer 36:916-924 (Pubitemid 30214143)
-
(2000)
European Journal of Cancer
, vol.36
, Issue.7
, pp. 916-924
-
-
Peters, G.J.1
Van Triest, B.2
Backus, H.H.J.3
Kuiper, C.M.4
Van Der Wilt, C.L.5
Pinedo, H.M.6
-
22
-
-
0034887884
-
Cell cycle-mediated drug resistance: An emerging concept in cancer therapy
-
Shah MA, Schwartz GK (2001) Cell cycle-mediated drug resistance: an emerging concept in cancer therapy. Clin Cancer Res 7:2168-2181 (Pubitemid 32751613)
-
(2001)
Clinical Cancer Research
, vol.7
, Issue.8
, pp. 2168-2181
-
-
Shah, M.A.1
Schwartz, G.K.2
-
23
-
-
2542422438
-
Structure, recognition, and processing of cisplatin-DNA adducts
-
Jamieson ER, Lippard SJ (1999) Structure, recognition, and processing of cisplatin-DNA adducts. Chem Rev 99:2467-2498
-
(1999)
Chem Rev
, vol.99
, pp. 2467-2498
-
-
Jamieson, E.R.1
Lippard, S.J.2
-
24
-
-
77950177827
-
Mechanisms of resistance to anti-EGFR monoclonal antibody treatment in metastatic colorectal cancer
-
Saridaki Z, Georgoulias V, Souglakos J (2010) Mechanisms of resistance to anti-EGFR monoclonal antibody treatment in metastatic colorectal cancer. World J Gastroenterol 16:1177-1187
-
(2010)
World J Gastroenterol
, vol.16
, pp. 1177-1187
-
-
Saridaki, Z.1
Georgoulias, V.2
Souglakos, J.3
-
25
-
-
75349110547
-
Weekly paclitaxel and trastuzumab as a fi rst-line therapy in patients with HER2-overexpressing metastatic breast cancer: Magnitude of HER2/neu amplifi cation as a predictive factor for effi cacy
-
Han HS, Kim JS, Park JH et al (2009) Weekly paclitaxel and trastuzumab as a fi rst-line therapy in patients with HER2-overexpressing metastatic breast cancer: magnitude of HER2/neu amplifi cation as a predictive factor for effi cacy. J Korean Med Sci 24:910-917
-
(2009)
J Korean Med Sci
, vol.24
, pp. 910-917
-
-
Han, H.S.1
Kim, J.S.2
Park, J.H.3
-
26
-
-
41149094150
-
Effect of frequently used chemotherapeutic drugs on cytotoxic activity of human cytotoxic T-lymphocytes
-
DOI 10.1097/CJI.0b013e3181628b76
-
Markasz L, Skribek H, Uhlin M et al (2008) Effect of frequently used chemotherapeutic drugs on cytotoxic activity of human cytotoxic T-lymphocytes. J Immunother 31:283-293 (Pubitemid 351441005)
-
(2008)
Journal of Immunotherapy
, vol.31
, Issue.3
, pp. 283-293
-
-
Markasz, L.1
Skribek, H.2
Uhlin, M.3
Otvos, R.4
Flaberg, E.5
Eksborg, S.6
Olah, E.7
Stuber, G.8
Szekely, L.9
-
28
-
-
45749134564
-
The anticancer immune response: Indispensable for therapeutic success?
-
DOI 10.1172/JCI35180
-
Zitvogel L, Apetoh L, Ghiringhelli F et al (2008) The anticancer immune response: indispensable for therapeutic success? J Clin Invest 118:1991-2001. Review (Pubitemid 351872317)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.6
, pp. 1991-2001
-
-
Zitvogel, L.1
Apetoh, L.2
Ghiringhelli, F.3
Andre, F.4
Tesniere, A.5
Kroemer, G.6
-
29
-
-
71849088755
-
The immunologic aspects in advanced ovarian cancer patients treated with paclitaxel and carboplatin chemotherapy
-
Wu X, Feng QM, Wang Y et al (2010) The immunologic aspects in advanced ovarian cancer patients treated with paclitaxel and carboplatin chemotherapy. Cancer Immunol Immunother 59:279-291
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 279-291
-
-
Wu, X.1
Feng, Q.M.2
Wang, Y.3
-
30
-
-
0035988623
-
Immune modulation by ionizing radiation and its implications for cancer immunotherapy
-
DOI 10.2174/1381612023394089
-
Friedman EJ (2002) Immune modulation by ionizing radiation and its implications for cancer immunotherapy. Curr Pharm Des 8:1765-1780 (Pubitemid 34846202)
-
(2002)
Current Pharmaceutical Design
, vol.8
, Issue.19
, pp. 1765-1780
-
-
Friedman, E.J.1
-
31
-
-
33747616867
-
Gamma-radiation upregulates MHC class I/II and ICAM-I molecules in multiple myeloma cell lines and primary tumors
-
DOI 10.1290/0508054.1
-
Chiriva-Internati M, Grizzi F, Pinkston J et al (2006) Gamma-radiation upregulates MHC class I/II and ICAM-I molecules in multiple myeloma cell lines and primary tumors. In Vitro Cell Dev Biol Anim 42:89-95 (Pubitemid 44264512)
-
(2006)
Vitro Cellular and Developmental Biology - Animal
, vol.42
, Issue.3-4
, pp. 89-95
-
-
Chiriva-Internati, M.1
Grizzi, F.2
Pinkston, J.3
Morrow, K.J.4
D'Cunha, N.5
Frezza, E.E.6
Muzzio, P.C.7
Kast, W.M.8
Cobos, E.9
-
32
-
-
0024297490
-
Effect of radiation on the expression of carcinoembryonic antigen on the membranes of human gastric adenocarcinoma cells - Immunological study using monoclonal antibodies
-
Hareyama M, Imai K, Ban T et al (1988) Effect of radiation on the expression of carcinoembryonic antigen on the membranes of human gastric adenocarcinoma cells - immunological study using monoclonal antibodies. Nippon Igaku Hoshasen Gakkai Zasshi 48:1572-1574
-
(1988)
Nippon Igaku Hoshasen Gakkai Zasshi
, vol.48
, pp. 1572-1574
-
-
Hareyama, M.1
Imai, K.2
Ban, T.3
-
33
-
-
0030877151
-
Late and persistent up-regulation of intercellular adhesion molecule-1 (ICAM-1) expression by ionizing radiation in human endothelial cells in vitro
-
DOI 10.1080/095530097143428
-
Gaugler MH, Squiban C, van der Meeren A et al (1997) Late and persistent up-regulation of intercellular adhesion molecule-1 (ICAM-1) expression by ionizing radiation in human endothelial cells in vitro. Int J Radiat Biol 72:201-209 (Pubitemid 27339415)
-
(1997)
International Journal of Radiation Biology
, vol.72
, Issue.2
, pp. 201-209
-
-
Gaugler, M.-H.1
Squiban, C.2
Van Der Meeren, A.3
Bertho, J.-M.4
Vandamme, M.5
Mouthon, M.-A.6
-
34
-
-
7444258053
-
Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes
-
DOI 10.1158/0008-5472.CAN-04-1525
-
Garnett CT, Palena C, Chakraborty M et al (2004) Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes. Cancer Res 64:7985-7994 (Pubitemid 39446933)
-
(2004)
Cancer Research
, vol.64
, Issue.21
, pp. 7985-7994
-
-
Garnett, C.T.1
Palena, C.2
Chakarborty, M.3
Tsang, K.-Y.4
Schlom, J.5
Hodge, J.W.6
-
35
-
-
33744803712
-
Phase I trial of the trifunctional anti-HER2 x anti-CD3 antibody ertumaxomab in metastatic breast cancer
-
DOI 10.1158/1078-0432.CCR-05-2436
-
Kiewe P, Hasmüller S, Kahlert S et al (2006) Phase I trial of the trifunctional anti-HER2 x anti-CD3 antibody ertumaxomab in metastatic breast cancer. Clin Cancer Res 12:3085-3091 (Pubitemid 43837355)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.10
, pp. 3085-3091
-
-
Kiewe, P.1
Hasmuller, S.2
Kahlert, S.3
Heinrigs, M.4
Rack, B.5
Marme, A.6
Korfel, A.7
Jager, M.8
Lindhofer, H.9
Sommer, H.10
Thiel, E.11
Untch, M.12
-
36
-
-
77953672220
-
Safety of catumaxomab: Cytokine-release-related symptoms as a possible predictive factor for effi cacy in a pivotal phase II/III trial in malignant ascites
-
Abstract
-
Bokemeyer C, Heiss M, Gamperl H et al (2009) Safety of catumaxomab: cytokine-release-related symptoms as a possible predictive factor for effi cacy in a pivotal phase II/III trial in malignant ascites. J Clin Oncol 27[Suppl]:Abstract 3036
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL.
, pp. 3036
-
-
Bokemeyer, C.1
Heiss, M.2
Gamperl, H.3
-
37
-
-
0022553450
-
Direct and indirect effects of human recombinant γ-interferon on tumor cells in a clonogenic assay
-
Saito T, Berens ME, Welander CE (1986) Direct and indirect effects of human recombinant gamma-interferon on tumor cells in a clonogenic assay. Cancer Res 46:1142-1147 (Pubitemid 16048245)
-
(1986)
Cancer Research
, vol.46
, Issue.3
, pp. 1142-1147
-
-
Saito, T.1
Berens, M.E.2
Welander, C.E.3
-
38
-
-
17844384517
-
Trifunctional bispecific antibody-induced tumor cell lysis of squamous cell carcinomas of the upper aerodigestive tract
-
DOI 10.1002/hed.20170
-
Gronau SS, Schmitt M, Thess B et al (2005) Trifunctional bispecific antibody-induced tumor cell lysis of squamous cell carcinomas of the upper aerodigestive tract. Head Neck 27: 376-382 (Pubitemid 40593891)
-
(2005)
Head and Neck
, vol.27
, Issue.5
, pp. 376-382
-
-
Gronau, S.S.1
Schmitt, M.2
Thess, B.3
Reinhardt, P.4
Wiesneth, M.5
Schmitt, A.6
Riechelmann, H.7
-
39
-
-
16644394804
-
Opsonization with a trifunctional bispecifi c (alphaCD3 × alphaEpCAM) antibody results in efficient lysis in vitro and in vivo of EpCAM positive tumor cells by cytotoxic T lymphocytes
-
Schmitt M, Schmitt A, Reinhardt P et al (2004) Opsonization with a trifunctional bispecifi c (alphaCD3 × alphaEpCAM) antibody results in efficient lysis in vitro and in vivo of EpCAM positive tumor cells by cytotoxic T lymphocytes. Int J Oncol 25:841-848
-
(2004)
Int J Oncol
, vol.25
, pp. 841-848
-
-
Schmitt, M.1
Schmitt, A.2
Reinhardt, P.3
-
40
-
-
70349644110
-
Test system for trifunctional antibodies in 3D MCTS culture
-
Hirschhaeuser F, Leidig T, Rodday B et al (2009) Test system for trifunctional antibodies in 3D MCTS culture. J Biomol Screen 14:980-990
-
(2009)
J Biomol Screen
, vol.14
, pp. 980-990
-
-
Hirschhaeuser, F.1
Leidig, T.2
Rodday, B.3
|