Putative factors that may modulate the effect of exercise on liver fat: Insights from animal studies

Journal of Nutrition and Metabolism

Volumn 2012, Issue , 2012, Pages

  Magkos, Faidon ^a,b,c  

^a HAROKOPIO UNIVERSITY   (Greece)

^b HARVARD MEDICAL SCHOOL   (United States)

^c WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 84856030628     PISSN: 20900724     EISSN: 20900732     Source Type: Journal    
DOI: 10.1155/2012/827417     Document Type: Review

References (50)

1. Adams L. A., Lymp J. F., Sauver J. S., Sanderson S. O., Lindor K. D., Feldstein A., Angulo P., The natural history of nonalcoholic fatty liver disease: a population-based cohort study. Gastroenterology 2005 129 1 113 121 2-s2.0-22344452893 10.1053/j.gastro.2005.04.014 (Pubitemid 41002048)
2. Hsiao P. J., Kuo K. K., Shin S. J., Yang Y. H., Lin W. Y., Yang J. F., Chiu C. C., Chuang W. L., Tsai T. R., Yu M. L., Significant correlations between severe fatty liver and risk factors for metabolic syndrome. Journal of Gastroenterology and Hepatology 2007 22 12 2118 2123 2-s2.0-36348948428 10.1111/j.1440-1746.2006.04698.x (Pubitemid 350145601)
3. Targher G., Arcaro G., Non-alcoholic fatty liver disease and increased risk of cardiovascular disease. Atherosclerosis 2007 191 2 235 240 2-s2.0-33947108446 10.1016/j.atherosclerosis.2006.08.021 (Pubitemid 46400718)
4. Fabbrini E., Sullivan S., Klein S., Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications. Hepatology 2010 51 2 679 689 2-s2.0-75449094816 10.1002/hep.23280
5. Speliotes E. K., Massaro J. M., Hoffmann U., Vasan R. S., Meigs J. B., Sahani D. V., Hirschhorn J. N., O'Donnell C. J., Fox C. S., Fatty liver is associated with dyslipidemia and dysglycemia independent of visceral fat: the Framingham heart study. Hepatology 2010 51 6 1979 1987 2-s2.0-77952680758 10.1002/hep.23593
6. Fabbrini E., Magkos F., Mohammed B. S., Pietka T., Abumrad N. A., Patterson B. W., Okunade A., Klein S., Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity. Proceedings of the National Academy of Sciences of the United States of America 2009 106 36 15430 15435 2-s2.0-70349326750 10.1073/pnas.0904944106
7. Magkos F., Basal very low-density lipoprotein metabolism in response to exercise: mechanisms of hypotriacylglycerolemia. Progress in Lipid Research 2009 48 3-4 171 190 2-s2.0-67349083256 10.1016/j.plipres.2009.02.003
8. Magkos F., Sidossis L. S., Exercise and insulin sensitivity: where do we stand? You'd better run! European Journal of Endocrinology 2008 4 1 22 25
9. Caldwell S., Lazo M., Is exercise an effective treatment for NASH? Knowns and unknowns. Annals of Hepatology 2009 8 1 S60 S66 2-s2.0-66749112908
10. Spassiani N. A., Kuk J. L., Exercise and the fatty liver. Applied Physiology, Nutrition and Metabolism 2008 33 4 802 807 2-s2.0-48649109712 10.1139/H08-059
11. Magkos F., Exercise and fat accumulation in the human liver. Current Opinion in Lipidology 2010 21 6 507 517 2-s2.0-78649369764 10.1097/MOL. 0b013e32833ea912
12. Ahrens R. A., Bishop C. L., Berdanier C. D., Effect of age and dietary carbohydrate source on the responses of rats to forced exercise. Journal of Nutrition 1972 102 2 241 247 2-s2.0-0015295715
13. Barakat H. A., Carpenter J. W., Lennon Y. A., Hanna W. R., O'Brien K. F., Dohm G. L., The effects of exercise on lipogenic enzyme activity and glyceride synthesis by liver homogenates of diabetic rats. Metabolism 1987 36 10 983 987 2-s2.0-0023200583 (Pubitemid 17160519)
14. Cha Y.-S., Sohn H.-S., Daily J. W. III, Oh S.-H., Effects of exercise training and/or high fat diet on lipid metabolism and carnitine concentrations in rats. Nutrition Research 1999 19 6 937 945 2-s2.0-0033152533 10.1016/S0271-5317(99)00054-8 (Pubitemid 29283916)
15. Chapados N. A., Seelaender M., Levy E., Lavoie J. M., Effects of exercise training on hepatic microsomal triglyceride transfer protein content in rats. Hormone and Metabolic Research 2009 41 4 287 293 2-s2.0-65649122273 10.1055/s-0028-1102937
16. Charbonneau A., Couturier K., Gauthier M. S., Lavoie J. M., Evidence of hepatic glucagon resistance associated with hepatic steatosis: reversal effect of training. International Journal of Sports Medicine 2005 26 6 432 441 2-s2.0-23644442053 10.1055/s-2004-821225 (Pubitemid 41117061)
17. Fukuda N., Tojho M., Hidaka T., Sho H., Sugano M., Reciprocal responses to exercise in hepatic ketogenesis and lipid secretion in the rat. Annals of Nutrition and Metabolism 1991 35 4 233 241 2-s2.0-0025901052
18. Gauthier M. S., Couturier K., Latour J. G., Lavoie J. M., Concurrent exercise prevents high-fat-diet-induced macrovesicular hepatic steatosis. Journal of Applied Physiology 2003 94 6 2127 2134 2-s2.0-0038517194 (Pubitemid 36605269)
19. Gauthier M. S., Couturier K., Charbonneau A., Lavoie J. M., ffects of introducing physical training in the course of a 16-week high-fat diet regimen on hepatic steatosis, adipose tissue fat accumulation, and plasma lipid profile. International Journal of Obesity and Related Metabolic Disorders 2004 28 8 1064 1071 (Pubitemid 38998714)
20. Gollisch K. S., Brandauer J., Jessen N., Effects of exercise training on subcutaneous and visceral adipose tissue in normal- and high-fat diet-fed rats. American Journal of Physiology-Endocrinology and Metabolism 2009 297 2 E495 E504
21. Hao L., Wang Y., Duan Y., Bu S., Effects of treadmill exercise training on liver fat accumulation and estrogen receptor alpha expression in intact and ovariectomized rats with or without estrogen replacement treatment. European Journal of Applied Physiology 2010 109 5 879 886 2-s2.0-77954144200 10.1007/s00421-010-1426-6
22. Karanth J., Jeevaratnam K., Effect of dietary lipid, carnitine and exercise on lipid profile in rat blood, liver and muscle. Indian Journal of Experimental Biology 2009 47 9 748 753 2-s2.0-70349306897
23. Lessard S. J., Rivas D. A., Chen Z. P., Bonen A., Febbraio M. A., Reeder D. W., Kemp B. E., Yaspelkis B. B., Hawley J. A., Tissue-specific effects of rosiglitazone and exercise in the treatment of lipid-induced insulin resistance. Diabetes 2007 56 7 1856 1864 2-s2.0-34347390598 10.2337/db06-1065 (Pubitemid 47025459)
24. Lira F. S., Tavares F. L., Yamashita A. S., Koyama C. H., Alves M. J., Caperuto E. C., Batista M. L., Seelaender M., Effect of endurance training upon lipid metabolism in the liver of cachectic tumour-bearing rats. Cell Biochemistry and Function 2008 26 6 701 708 2-s2.0-52649169289 10.1002/cbf.1495
25. Morifuji M., Sanbongi C., Sugiura K., Dietary soya protein intake and exercise training have an additive effect on skeletal muscle fatty acid oxidation enzyme activities and mRNA levels in rats. The British Journal of Nutrition 2006 96 3 469 475 2-s2.0-33750143285
26. Narayan K. A., McMullen J. J., Butler D. P., Effect of exercise on tissue lipids and serum lipoproteins of rats fed two levels of fat. Journal of Nutrition 1975 105 5 581 587 2-s2.0-0016704508
27. Petridou A., Nikolaidis M. G., Matsakas A., Schulz T., Michna H., Mougios V., Effect of exercise training on the fatty acid composition of lipid classes in rat liver, skeletal muscle, and adipose tissue. European Journal of Applied Physiology 2005 94 1-2 84 92 2-s2.0-23244462810 10.1007/s00421-004-1294-z (Pubitemid 41166755)
28. Pighon A., Barsalani R., Yasari S., Prud'Homme D., Lavoie J. M., Does exercise training prior to ovariectomy protect against liver and adipocyte fat accumulation in rats? Climacteric 2010 13 3 238 248 2-s2.0-77951866235 10.3109/13697130903009203
29. Rector R. S., Thyfault J. P., Morris R. T., Laye M. J., Borengasser S. J., Booth F. W., Ibdah J. A., Daily exercise increases hepatic fatty acid oxidation and prevents steatosis in Otsuka Long-Evans Tokushima Fatty rats. American Journal of Physiology 2008 294 3 G619 G626 2-s2.0-41549166521 10.1152/ajpgi.00428.2007 (Pubitemid 351468778)
30. Rothfeld B., Levine A., Varady A., The effect of exercise on lipid deposition in the rat. Biochemical Medicine 1977 18 2 206 209 2-s2.0-0017649906 (Pubitemid 8213841)
31. Straczkowski M., Kowalska I., Dzienis-Straczkowska S., Kinalski M., Górski J., Kinalska I., The effect of exercise training on glucose tolerance and skeletal muscle triacylglycerol content in rats fed with a high-fat diet. Diabetes and Metabolism 2001 27 1 19 23 2-s2.0-0035096932 (Pubitemid 32198875)
32. Terao T., Fujise T., Nakano S., Effects of long-term exercise and high-cholesterol diet on lipid-lipoprotein metabolism in rats. Tokai Journal of Experimental and Clinical Medicine 1987 12 4 243 251 2-s2.0-0023498135
33. Tsutsumi K., Kusunoki M., Hara T., Okada K., Sakamoto S., Ohnaka M., Nakaya Y., Exercise improved accumulation of visceral fat and simultaneously impaired endothelium-dependent relaxation in old rats. Biological and Pharmaceutical Bulletin 2001 24 1 88 91 2-s2.0-0035156489 10.1248/bpb.24.88 (Pubitemid 32125010)
34. Vieira V. J., Valentine R. J., Wilund K. R., Antao N., Baynard T., Woods J. A., Effects of exercise and low-fat diet on adipose tissue inflammation and metabolic complications in obese mice. American Journal of Physiology- Endocrinology and Metabolism 2009 296 5 E1164 E1171
35. Vieira V. J., Valentine R. J., Wilund K. R., Woods J. A., Effects of diet and exercise on metabolic disturbances in high-fat diet-fed mice. Cytokine 2009 46 3 339 345 2-s2.0-67349210207 10.1016/j.cyto.2009.03.006
36. Yasari S., Paquette A., Charbonneau A., Gauthier M. S., Savard R., Lavoie J. M., Effects of ingesting a high-fat diet upon exercise-training cessation on fat accretion in the liver and adipose tissue of rats. Applied Physiology, Nutrition and Metabolism 2006 31 4 367 375 2-s2.0-33750315894 10.1139/H06-032 (Pubitemid 44621781)
37. Yasari S., Prud'Homme D., Wang D., Jankowski M., Levy É.., Gutkowska J., Lavoie J. M., Exercise training decreases hepatic SCD-1 gene expression and protein content in rats. Molecular and Cellular Biochemistry 2010 335 1-2 291 299 2-s2.0-75949107920 10.1007/s11010-009-0279-y
38. He Y., Zhang H., Fu F. H., The effects of swimming exercise on high-fat-diet-induced steatohepatitis. Journal of Sports Medicine and Physical Fitness 2008 48 2 259 265 2-s2.0-46349104762
39. Trudell J. R., Lin W. Q., Chrystof D. A., Kirshenbaum G., Ardies C. M., Induction of HSP72 in rat liver by chronic ethanol consumption combined with exercise: association with the prevention of ethanol-induced fatty liver by exercise. Alcoholism: Clinical and Experimental Research 1995 19 3 753 758 2-s2.0-0029027582 10.1111/j.1530-0277.1995.tb01578.x
40. Finucane F. M., Sharp S. J., Purslow L. R., Horton K., Horton J., Savage D. B., Brage S., Besson H., De Lucia Rolfe E., Sleigh A., Martin H. J., Aihie Sayer A., Cooper C., Ekelund U., Griffin S. J., Wareham N. J., The effects of aerobic exercise on metabolic risk, insulin sensitivity and intrahepatic lipid in healthy older people from the Hertfordshire Cohort Study: a randomised controlled trial. Diabetologia 2010 53 4 624 631 2-s2.0-77949266534 10.1007/s00125-009-1641-z
41. Bonekamp S., Barone B. B., Clark J., Stewart K. J., The effect of an exercise training intervention on hepatic steatosis. Hepatology 2008 48 supplement 1 806A
42. Charbonneau A., Melancon A., Lavoie C., Lavoie J. M., Alterations in hepatic glucagon receptor density and in Gs α and Gi α 2 protein content with diet-induced hepatic steatosis: effects of acute exercise. American Journal of Physiology-Endocrinology and Metabolism 2005 289 1 E8 E14 (Pubitemid 40874928)
43. Charbonneau A., Unson C. G., Lavoie J. M., High-fat diet-induced hepatic steatosis reduces glucagon receptor content in rat hepatocytes: potential interaction with acute exercise. Journal of Physiology 2007 579 1 255 267 2-s2.0-33846994380 10.1113/jphysiol.2006.121954
44. Haufe S., Engeli S., Budziarek P., Utz W., Schulz-Menger J., Hermsdorf M., Wiesner S., Otto C., Haas V., De Greiff A., Luft F. C., Boschmann M., Jordan J., Cardiorespiratory fitness and insulin sensitivity in overweight or obese subjects may be linked through intrahepatic lipid content. Diabetes 2010 59 7 1640 1647 2-s2.0-77954301990 10.2337/db09-1200
45. Maling H. M., Stern D. N., Altland P. D., Highman B., Brodie B. B., The physiologic role of the sympathetic nervous system in exercise. Journal of Pharmacology and Experimental Therapeutics 1966 154 1 35 45 2-s2.0-0013963368
46. Gorski J., Kiryluk T., The post-exercise recovery of triglycerides in rat tissues. European Journal of Applied Physiology and Occupational Physiology 1980 45 1 33 41 2-s2.0-0018931882 (Pubitemid 10009211)
47. Altland P. D., Highman B., Effects of exercise on serum enzyme values and tissues of rats. American Journal of Physiology 1961 201 393 395 2-s2.0-14444277963
48. Straczkowski M., Kowalska I., Górski J., Kinalska I., The effect of a single bout of exhaustive exercise on muscle carbohydrate and lipid metabolism in a rat model of type 2 diabetes mellitus. Acta Diabetologica 2000 37 1 47 53 2-s2.0-0034151876
49. Rector S. R., Thyfault J. P., Laye M. J., Morris T. R., Borengasser S. J., Uptergrove G. M., Chakravarthy M. V., Booth F. W., Ibdah J. A., Cessation of daily exercise dramatically alters precursors of hepatic steatosis in Otsuka Long-Evans Tokushima Fatty (OLETF) rats. Journal of Physiology 2008 586 17 4241 4249 2-s2.0-51749108218 10.1113/jphysiol.2008.156745
50. Lowney P., Lee V. M., Hansen R. J., Stern J. S., Effects of exercise, detraining, starvation, and refeeding on lipogenic capacity of Osborne-Mendel rat. American Journal of Physiology 1988 254 4 R648 R654 2-s2.0-0023900719